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Items: 1 to 20 of 49

1.

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.

Gao N, Le Lay J, Qin W, Doliba N, Schug J, Fox AJ, Smirnova O, Matschinsky FM, Kaestner KH.

Mol Endocrinol. 2010 Aug;24(8):1594-604. doi: 10.1210/me.2009-0513. Epub 2010 Jun 9.

2.

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis.

Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, Godwin AK, Korach KS, Visvader JE, Kaestner KH, Abdul-Karim FW, Montano MM, Keri RA.

Development. 2010 Jun;137(12):2045-54. doi: 10.1242/dev.043299.

3.

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation.

Santisteban P, Recacha P, Metzger DE, Zaret KS.

Dev Dyn. 2010 Mar;239(3):980-6. doi: 10.1002/dvdy.22217.

4.

The Fox genes in the liver: from organogenesis to functional integration.

Le Lay J, Kaestner KH.

Physiol Rev. 2010 Jan;90(1):1-22. doi: 10.1152/physrev.00018.2009. Review.

5.

Correlated changes between regulatory cis elements and condition-specific expression in paralogous gene families.

Singh LN, Hannenhalli S.

Nucleic Acids Res. 2010 Jan;38(3):738-49. doi: 10.1093/nar/gkp989. Epub 2009 Nov 19.

6.

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.

Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL.

Dev Biol. 2009 Sep 15;333(2):386-96. doi: 10.1016/j.ydbio.2009.07.006. Epub 2009 Jul 14.

7.

Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH.

Physiol Genomics. 2009 Jul 9;38(2):186-95. doi: 10.1152/physiolgenomics.90376.2008. Epub 2009 May 5.

8.

The evolution of Fox genes and their role in development and disease.

Hannenhalli S, Kaestner KH.

Nat Rev Genet. 2009 Apr;10(4):233-40. doi: 10.1038/nrg2523. Review.

9.

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.

10.

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.

Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M.

Genome Res. 2009 Mar;19(3):372-80. doi: 10.1101/gr.084582.108. Epub 2009 Jan 7.

11.

Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression.

Singh LN, Hannenhalli S.

PLoS One. 2008 Jun 4;3(6):e2345. doi: 10.1371/journal.pone.0002345.

12.

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription.

Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M.

Cell. 2008 Mar 21;132(6):958-70. doi: 10.1016/j.cell.2008.01.018.

13.

The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age.

Kittappa R, Chang WW, Awatramani RB, McKay RD.

PLoS Biol. 2007 Dec;5(12):e325.

14.

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells.

Gao N, White P, Doliba N, Golson ML, Matschinsky FM, Kaestner KH.

Cell Metab. 2007 Oct;6(4):267-79.

15.

Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.

Ferri AL, Lin W, Mavromatakis YE, Wang JC, Sasaki H, Whitsett JA, Ang SL.

Development. 2007 Aug;134(15):2761-9. Epub 2007 Jun 27.

16.

Foxa1-deficient mice exhibit impaired insulin secretion due to uncoupled oxidative phosphorylation.

Vatamaniuk MZ, Gupta RK, Lantz KA, Doliba NM, Matschinsky FM, Kaestner KH.

Diabetes. 2006 Oct;55(10):2730-6.

17.

The making of the liver: developmental competence in foregut endoderm and induction of the hepatogenic program.

Kaestner KH.

Cell Cycle. 2005 Sep;4(9):1146-8. Epub 2005 Sep 15. Review.

PMID:
16123587
18.

Foxa2 integrates the transcriptional response of the hepatocyte to fasting.

Zhang L, Rubins NE, Ahima RS, Greenbaum LE, Kaestner KH.

Cell Metab. 2005 Aug;2(2):141-8.

19.

From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response.

Laganière J, Deblois G, Lefebvre C, Bataille AR, Robert F, Giguère V.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11651-6. Epub 2005 Aug 8.

20.

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.

Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M.

Cell. 2005 Jul 15;122(1):33-43.

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