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Results: 1 to 20 of 53

1.

Subtle variations in Pten dose determine cancer susceptibility.

Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J, Pandolfi PP.

Nat Genet. 2010 May;42(5):454-8. doi: 10.1038/ng.556. Epub 2010 Apr 18.

PMID:
20400965
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Integrative analysis of the melanoma transcriptome.

Berger MF, Levin JZ, Vijayendran K, Sivachenko A, Adiconis X, Maguire J, Johnson LA, Robinson J, Verhaak RG, Sougnez C, Onofrio RC, Ziaugra L, Cibulskis K, Laine E, Barretina J, Winckler W, Fisher DE, Getz G, Meyerson M, Jaffe DB, Gabriel SB, Lander ES, Dummer R, Gnirke A, Nusbaum C, Garraway LA.

Genome Res. 2010 Apr;20(4):413-27. doi: 10.1101/gr.103697.109. Epub 2010 Feb 23.

PMID:
20179022
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Complex landscapes of somatic rearrangement in human breast cancer genomes.

Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Børresen-Dale AL, Campbell PJ, Futreal PA, Stratton MR.

Nature. 2009 Dec 24;462(7276):1005-10. doi: 10.1038/nature08645.

PMID:
20033038
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A broadly conserved pathway generates 3'UTR-directed primary piRNAs.

Robine N, Lau NC, Balla S, Jin Z, Okamura K, Kuramochi-Miyagawa S, Blower MD, Lai EC.

Curr Biol. 2009 Dec 29;19(24):2066-76. doi: 10.1016/j.cub.2009.11.064.

PMID:
20022248
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements.

Lal A, Navarro F, Maher CA, Maliszewski LE, Yan N, O'Day E, Chowdhury D, Dykxhoorn DM, Tsai P, Hofmann O, Becker KG, Gorospe M, Hide W, Lieberman J.

Mol Cell. 2009 Sep 11;35(5):610-25. doi: 10.1016/j.molcel.2009.08.020.

PMID:
19748357
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.

Mayr C, Bartel DP.

Cell. 2009 Aug 21;138(4):673-84. doi: 10.1016/j.cell.2009.06.016.

PMID:
19703394
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.

Kato M, Putta S, Wang M, Yuan H, Lanting L, Nair I, Gunn A, Nakagawa Y, Shimano H, Todorov I, Rossi JJ, Natarajan R.

Nat Cell Biol. 2009 Jul;11(7):881-9. doi: 10.1038/ncb1897. Epub 2009 Jun 21.

PMID:
19543271
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo.

Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC.

Genes Dev. 2009 Jun 1;23(11):1327-37. doi: 10.1101/gad.1777409.

PMID:
19487573
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression.

Kim J, Bartel DP.

Nat Biotechnol. 2009 May;27(5):472-7. doi: 10.1038/nbt.1540. Epub 2009 Apr 26.

PMID:
19396161
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Redefining microRNA targets.

Seitz H.

Curr Biol. 2009 May 26;19(10):870-3. doi: 10.1016/j.cub.2009.03.059. Epub 2009 Apr 16.

PMID:
19375315
[PubMed - indexed for MEDLINE]
Free Article
11.

Many roads to maturity: microRNA biogenesis pathways and their regulation.

Winter J, Jung S, Keller S, Gregory RI, Diederichs S.

Nat Cell Biol. 2009 Mar;11(3):228-34. doi: 10.1038/ncb0309-228. Review.

PMID:
19255566
[PubMed - indexed for MEDLINE]
12.

MicroRNAs and cancer: short RNAs go a long way.

Ventura A, Jacks T.

Cell. 2009 Feb 20;136(4):586-91. doi: 10.1016/j.cell.2009.02.005.

PMID:
19239879
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A 3'-untranslated region (3'UTR) induces organ adhesion by regulating miR-199a* functions.

Lee DY, Shatseva T, Jeyapalan Z, Du WW, Deng Z, Yang BB.

PLoS One. 2009;4(2):e4527. doi: 10.1371/journal.pone.0004527. Epub 2009 Feb 18.

PMID:
19223980
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs.

Gu S, Jin L, Zhang F, Sarnow P, Kay MA.

Nat Struct Mol Biol. 2009 Feb;16(2):144-50. doi: 10.1038/nsmb.1552. Epub 2009 Feb 1.

PMID:
19182800
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.

Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES.

Nature. 2009 Mar 12;458(7235):223-7. doi: 10.1038/nature07672. Epub 2009 Feb 1.

PMID:
19182780
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MicroRNAs: target recognition and regulatory functions.

Bartel DP.

Cell. 2009 Jan 23;136(2):215-33. doi: 10.1016/j.cell.2009.01.002. Review.

PMID:
19167326
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes.

Balasubramanian S, Zheng D, Liu YJ, Fang G, Frankish A, Carriero N, Robilotto R, Cayting P, Gerstein M.

Genome Biol. 2009;10(1):R2. doi: 10.1186/gb-2009-10-1-r2. Epub 2009 Jan 5.

PMID:
19123937
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation.

Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I.

Nature. 2008 Oct 23;455(7216):1124-8. doi: 10.1038/nature07299. Epub 2008 Sep 17. Erratum in: Nature. 2009 Mar 26;458(7237):538.

PMID:
18806776
[PubMed - indexed for MEDLINE]
19.

The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs.

Okamura K, Chung WJ, Lai EC.

Cell Cycle. 2008 Sep 15;7(18):2840-5. Epub 2008 Sep 5. Review.

PMID:
18769156
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The impact of microRNAs on protein output.

Baek D, Villén J, Shin C, Camargo FD, Gygi SP, Bartel DP.

Nature. 2008 Sep 4;455(7209):64-71. doi: 10.1038/nature07242. Epub 2008 Jul 30.

PMID:
18668037
[PubMed - indexed for MEDLINE]
Free PMC Article
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