Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 20

1.

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Zhou C, Verma S, Blumberg B.

Nucl Recept Signal. 2009;7:e001. doi: 10.1621/nrs.07001. Epub 2009 Jan 16. Review.

PMID:
19240808
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Epigenetic regulation of transcriptional activity of pregnane X receptor by protein arginine methyltransferase 1.

Xie Y, Ke S, Ouyang N, He J, Xie W, Bedford MT, Tian Y.

J Biol Chem. 2009 Apr 3;284(14):9199-205. doi: 10.1074/jbc.M806193200. Epub 2009 Jan 13.

PMID:
19144646
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells.

Verma S, Tabb MM, Blumberg B.

BMC Cancer. 2009 Jan 5;9:3. doi: 10.1186/1471-2407-9-3.

PMID:
19123943
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Expanding the roles for pregnane X receptor in cancer: proliferation and drug resistance in ovarian cancer.

Gupta D, Venkatesh M, Wang H, Kim S, Sinz M, Goldberg GL, Whitney K, Longley C, Mani S.

Clin Cancer Res. 2008 Sep 1;14(17):5332-40. doi: 10.1158/1078-0432.CCR-08-1033.

PMID:
18765524
[PubMed - indexed for MEDLINE]
Free Article
5.

Pregnane X receptor protects HepG2 cells from BaP-induced DNA damage.

Naspinski C, Gu X, Zhou GD, Mertens-Talcott SU, Donnelly KC, Tian Y.

Toxicol Sci. 2008 Jul;104(1):67-73. doi: 10.1093/toxsci/kfn058. Epub 2008 Apr 1.

PMID:
18381355
[PubMed - indexed for MEDLINE]
Free Article
6.

Pregnane X receptor is essential for normal progression of liver regeneration.

Dai G, He L, Bu P, Wan YJ.

Hepatology. 2008 Apr;47(4):1277-87. doi: 10.1002/hep.22129.

PMID:
18167061
[PubMed - indexed for MEDLINE]
7.

Role of the PXR gene locus in inflammatory bowel diseases.

Martínez A, Márquez A, Mendoza J, Taxonera C, Fernández-Arquero M, Díaz-Rubio M, de la Concha EG, Urcelay E.

Inflamm Bowel Dis. 2007 Dec;13(12):1484-7.

PMID:
17828778
[PubMed - indexed for MEDLINE]
8.

Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression.

Shah YM, Ma X, Morimura K, Kim I, Gonzalez FJ.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1114-22. Epub 2006 Dec 14.

PMID:
17170021
[PubMed - indexed for MEDLINE]
Free Article
9.

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.

Sharma N, Timmers C, Trikha P, Saavedra HI, Obery A, Leone G.

J Biol Chem. 2006 Nov 24;281(47):36124-31. Epub 2006 Sep 27.

PMID:
17008321
[PubMed - indexed for MEDLINE]
Free Article
10.

Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation.

Zhou C, Tabb MM, Nelson EL, Grün F, Verma S, Sadatrafiei A, Lin M, Mallick S, Forman BM, Thummel KE, Blumberg B.

J Clin Invest. 2006 Aug;116(8):2280-2289.

PMID:
16841097
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.

Gu X, Ke S, Liu D, Sheng T, Thomas PE, Rabson AB, Gallo MA, Xie W, Tian Y.

J Biol Chem. 2006 Jun 30;281(26):17882-9. Epub 2006 Apr 10.

PMID:
16608838
[PubMed - indexed for MEDLINE]
Free Article
12.

The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.

Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PW, O'Donoghue D, O'Sullivan M, O'Morain C, Mahmud N, Wikström AC, Kelleher D, McManus R.

Gastroenterology. 2006 Feb;130(2):341-8; quiz 592.

PMID:
16472590
[PubMed - indexed for MEDLINE]
13.

Lost in transcription: p21 repression, mechanisms, and consequences.

Gartel AL, Radhakrishnan SK.

Cancer Res. 2005 May 15;65(10):3980-5. Review.

PMID:
15899785
[PubMed - indexed for MEDLINE]
Free Article
14.

Overview and pathogenesis of celiac disease.

Kagnoff MF.

Gastroenterology. 2005 Apr;128(4 Suppl 1):S10-8. Review. No abstract available.

PMID:
15825116
[PubMed - indexed for MEDLINE]
15.

Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes.

Langmann T, Moehle C, Mauerer R, Scharl M, Liebisch G, Zahn A, Stremmel W, Schmitz G.

Gastroenterology. 2004 Jul;127(1):26-40.

PMID:
15236169
[PubMed - indexed for MEDLINE]
16.

Induction of drug metabolism: the role of nuclear receptors.

Handschin C, Meyer UA.

Pharmacol Rev. 2003 Dec;55(4):649-73. Review.

PMID:
14657421
[PubMed - indexed for MEDLINE]
Free Article
17.

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

Sonoda J, Xie W, Rosenfeld JM, Barwick JL, Guzelian PS, Evans RM.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13801-6. Epub 2002 Oct 7.

PMID:
12370413
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

SXR, a novel steroid and xenobiotic-sensing nuclear receptor.

Blumberg B, Sabbagh W Jr, Juguilon H, Bolado J Jr, van Meter CM, Ong ES, Evans RM.

Genes Dev. 1998 Oct 15;12(20):3195-205.

PMID:
9784494
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction.

Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Bäckman M, Ohlsson R, Postlind H, Blomquist P, Berkenstam A.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12208-13.

PMID:
9770465
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA.

J Clin Invest. 1998 Sep 1;102(5):1016-23.

PMID:
9727070
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk