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Results: 1 to 20 of 41

1.

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

Janssen A, Kops GJ, Medema RH.

Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19108-13. doi: 10.1073/pnas.0904343106. Epub 2009 Oct 23.

PMID:
19855003
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Dividing the goods: co-ordination of chromosome biorientation and mitotic checkpoint signalling by mitotic kinases.

Kops GJ.

Biochem Soc Trans. 2009 Oct;37(Pt 5):971-5. doi: 10.1042/BST0370971. Review.

PMID:
19754434
[PubMed - indexed for MEDLINE]
3.

Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation.

Bourhis E, Lingel A, Phung Q, Fairbrother WJ, Cochran AG.

Biochemistry. 2009 Jul 28;48(29):6783-93. doi: 10.1021/bi900530v.

PMID:
19530738
[PubMed - indexed for MEDLINE]
4.

Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding.

Kulukian A, Han JS, Cleveland DW.

Dev Cell. 2009 Jan;16(1):105-17. doi: 10.1016/j.devcel.2008.11.005.

PMID:
19154722
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates.

Liu D, Vader G, Vromans MJ, Lampson MA, Lens SM.

Science. 2009 Mar 6;323(5919):1350-3. doi: 10.1126/science.1167000. Epub 2009 Jan 15.

PMID:
19150808
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes.

Jelluma N, Brenkman AB, McLeod I, Yates JR 3rd, Cleveland DW, Medema RH, Kops GJ.

PLoS One. 2008 Jun 11;3(6):e2415. doi: 10.1371/journal.pone.0002415.

PMID:
18545697
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores.

Tighe A, Staples O, Taylor S.

J Cell Biol. 2008 Jun 16;181(6):893-901. doi: 10.1083/jcb.200712028. Epub 2008 Jun 9.

PMID:
18541701
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment.

Jelluma N, Brenkman AB, van den Broek NJ, Cruijsen CW, van Osch MH, Lens SM, Medema RH, Kops GJ.

Cell. 2008 Jan 25;132(2):233-46. doi: 10.1016/j.cell.2007.11.046.

PMID:
18243099
[PubMed - indexed for MEDLINE]
Free Article
9.

Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint.

Kang J, Chen Y, Zhao Y, Yu H.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20232-7. Epub 2007 Dec 14.

PMID:
18083840
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism.

Maure JF, Kitamura E, Tanaka TU.

Curr Biol. 2007 Dec 18;17(24):2175-82. Epub 2007 Nov 29.

PMID:
18060784
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chromosomal passengers: conducting cell division.

Ruchaud S, Carmena M, Earnshaw WC.

Nat Rev Mol Cell Biol. 2007 Oct;8(10):798-812. Review.

PMID:
17848966
[PubMed - indexed for MEDLINE]
12.

Mps1 activation loop autophosphorylation enhances kinase activity.

Mattison CP, Old WM, Steiner E, Huneycutt BJ, Resing KA, Ahn NG, Winey M.

J Biol Chem. 2007 Oct 19;282(42):30553-61. Epub 2007 Aug 28.

PMID:
17728254
[PubMed - indexed for MEDLINE]
Free Article
13.

The spindle-assembly checkpoint in space and time.

Musacchio A, Salmon ED.

Nat Rev Mol Cell Biol. 2007 May;8(5):379-93. Epub 2007 Apr 11. Review.

PMID:
17426725
[PubMed - indexed for MEDLINE]
14.

Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells.

Liu ST, Rattner JB, Jablonski SA, Yen TJ.

J Cell Biol. 2006 Oct 9;175(1):41-53.

PMID:
17030981
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Phosphate-binding tag, a new tool to visualize phosphorylated proteins.

Kinoshita E, Kinoshita-Kikuta E, Takiyama K, Koike T.

Mol Cell Proteomics. 2006 Apr;5(4):749-57. Epub 2005 Dec 11.

PMID:
16340016
[PubMed - indexed for MEDLINE]
Free Article
16.

On the road to cancer: aneuploidy and the mitotic checkpoint.

Kops GJ, Weaver BA, Cleveland DW.

Nat Rev Cancer. 2005 Oct;5(10):773-85. Review.

PMID:
16195750
[PubMed - indexed for MEDLINE]
17.

Ablation of the spindle assembly checkpoint by a compound targeting Mps1.

Schmidt M, Budirahardja Y, Klompmaker R, Medema RH.

EMBO Rep. 2005 Sep;6(9):866-72.

PMID:
16113653
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The spindle checkpoint: tension versus attachment.

Pinsky BA, Biggins S.

Trends Cell Biol. 2005 Sep;15(9):486-93. Review.

PMID:
16084093
[PubMed - indexed for MEDLINE]
19.

A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes.

Dorer RK, Zhong S, Tallarico JA, Wong WH, Mitchison TJ, Murray AW.

Curr Biol. 2005 Jun 7;15(11):1070-6.

PMID:
15936280
[PubMed - indexed for MEDLINE]
Free Article
20.

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

Kops GJ, Kim Y, Weaver BA, Mao Y, McLeod I, Yates JR 3rd, Tagaya M, Cleveland DW.

J Cell Biol. 2005 Apr 11;169(1):49-60.

PMID:
15824131
[PubMed - indexed for MEDLINE]
Free PMC Article

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