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Results: 13

1.

Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime.

Sanson B, Nachon F, Colletier JP, Froment MT, Toker L, Greenblatt HM, Sussman JL, Ashani Y, Masson P, Silman I, Weik M.

J Med Chem. 2009 Dec 10;52(23):7593-603. doi: 10.1021/jm900433t.

PMID:
19642642
[PubMed - indexed for MEDLINE]
2.

Structure of HI-6*sarin-acetylcholinesterase determined by X-ray crystallography and molecular dynamics simulation: reactivator mechanism and design.

Ekström F, Hörnberg A, Artursson E, Hammarström LG, Schneider G, Pang YP.

PLoS One. 2009 Jun 18;4(6):e5957. doi: 10.1371/journal.pone.0005957.

PMID:
19536291
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity.

Amitai G, Adani R, Yacov G, Yishay S, Teitlboim S, Tveria L, Limanovich O, Kushnir M, Meshulam H.

Toxicology. 2007 Apr 20;233(1-3):187-98. Epub 2006 Oct 13.

PMID:
17129656
[PubMed - indexed for MEDLINE]
4.

Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates.

Ekström F, Pang YP, Boman M, Artursson E, Akfur C, Börjegren S.

Biochem Pharmacol. 2006 Aug 28;72(5):597-607. Epub 2006 Jul 31.

PMID:
16876764
[PubMed - indexed for MEDLINE]
5.

Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding.

Bourne Y, Radic Z, Sulzenbacher G, Kim E, Taylor P, Marchot P.

J Biol Chem. 2006 Sep 29;281(39):29256-67. Epub 2006 Jul 12.

PMID:
16837465
[PubMed - indexed for MEDLINE]
Free Article
6.

Concentrations of selective metabolites of organophosphorus pesticides in the United States population.

Barr DB, Allen R, Olsson AO, Bravo R, Caltabiano LM, Montesano A, Nguyen J, Udunka S, Walden D, Walker RD, Weerasekera G, Whitehead RD Jr, Schober SE, Needham LL.

Environ Res. 2005 Nov;99(3):314-26.

PMID:
16307973
[PubMed - indexed for MEDLINE]
7.

Acetylcholinesterase. X. Mechanism of the catalysis of acylation reactions.

WILSON IB, BERGMANN F, NACHMANSOHN D.

J Biol Chem. 1950 Oct;186(2):781-90. No abstract available.

PMID:
14794673
[PubMed - indexed for MEDLINE]
Free Article
8.

A new and rapid colorimetric determination of acetylcholinesterase activity.

ELLMAN GL, COURTNEY KD, ANDRES V Jr, FEATHER-STONE RM.

Biochem Pharmacol. 1961 Jul;7:88-95. No abstract available.

PMID:
13726518
[PubMed - indexed for MEDLINE]
9.

Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition.

Wang Q, Chan TR, Hilgraf R, Fokin VV, Sharpless KB, Finn MG.

J Am Chem Soc. 2003 Mar 19;125(11):3192-3.

PMID:
12630856
[PubMed - indexed for MEDLINE]
10.

Reversibly bound and covalently attached ligands induce conformational changes in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase.

Shi J, Boyd AE, Radic Z, Taylor P.

J Biol Chem. 2001 Nov 9;276(45):42196-204. Epub 2001 Aug 21.

PMID:
11517229
[PubMed - indexed for MEDLINE]
Free Article
11.

Patterns and problems of deliberate self-poisoning in the developing world.

Eddleston M.

QJM. 2000 Nov;93(11):715-31. Review.

PMID:
11077028
[PubMed - indexed for MEDLINE]
Free Article
12.

Interaction kinetics of reversible inhibitors and substrates with acetylcholinesterase and its fasciculin 2 complex.

Radić Z, Taylor P.

J Biol Chem. 2001 Feb 16;276(7):4622-33. Epub 2000 Oct 17.

PMID:
11036076
[PubMed - indexed for MEDLINE]
Free Article
13.

Interactions of oxime reactivators with diethylphosphoryl adducts of human acetylcholinesterase and its mutant derivatives.

Grosfeld H, Barak D, Ordentlich A, Velan B, Shafferman A.

Mol Pharmacol. 1996 Sep;50(3):639-49.

PMID:
8794905
[PubMed - indexed for MEDLINE]

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