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Results: 1 to 20 of 24

1.

Anti-inflammatory treatment in AD mice protects against neuronal pathology.

Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A.

Exp Neurol. 2010 Jun;223(2):377-84. doi: 10.1016/j.expneurol.2009.07.032. Epub 2009 Aug 10.

PMID:
19679126
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Application of MRS to mouse models of neurodegenerative illness.

Choi JK, Dedeoglu A, Jenkins BG.

NMR Biomed. 2007 May;20(3):216-37. Review.

PMID:
17451183
[PubMed - indexed for MEDLINE]
3.

Elevated brain scyllo-inositol concentrations in patients with Alzheimer's disease.

Griffith HR, den Hollander JA, Stewart CC, Evanochko WT, Buchthal SD, Harrell LE, Zamrini EY, Brockington JC, Marson DC.

NMR Biomed. 2007 Dec;20(8):709-16.

PMID:
17295394
[PubMed - indexed for MEDLINE]
4.

Properties of scyllo-inositol as a therapeutic treatment of AD-like pathology.

Fenili D, Brown M, Rappaport R, McLaurin J.

J Mol Med (Berl). 2007 Jun;85(6):603-11. Epub 2007 Feb 6.

PMID:
17279347
[PubMed - indexed for MEDLINE]
5.

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles.

Oddo S, Vasilevko V, Caccamo A, Kitazawa M, Cribbs DH, LaFerla FM.

J Biol Chem. 2006 Dec 22;281(51):39413-23. Epub 2006 Oct 20.

PMID:
17056594
[PubMed - indexed for MEDLINE]
Free Article
6.

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

McLaurin J, Kierstead ME, Brown ME, Hawkes CA, Lambermon MH, Phinney AL, Darabie AA, Cousins JE, French JE, Lan MF, Chen F, Wong SS, Mount HT, Fraser PE, Westaway D, St George-Hyslop P.

Nat Med. 2006 Jul;12(7):801-8. Epub 2006 Jun 11.

PMID:
16767098
[PubMed - indexed for MEDLINE]
7.

Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy.

Marjanska M, Curran GL, Wengenack TM, Henry PG, Bliss RL, Poduslo JF, Jack CR Jr, Ugurbil K, Garwood M.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11906-10. Epub 2005 Aug 9.

PMID:
16091461
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span.

von Kienlin M, Künnecke B, Metzger F, Steiner G, Richards JG, Ozmen L, Jacobsen H, Loetscher H.

Neurobiol Dis. 2005 Feb;18(1):32-9.

PMID:
15649694
[PubMed - indexed for MEDLINE]
9.

Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile.

Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG.

Brain Res. 2004 Jun 25;1012(1-2):60-5.

PMID:
15158161
[PubMed - indexed for MEDLINE]
10.

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.

Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM.

Neuron. 2003 Jul 31;39(3):409-21.

PMID:
12895417
[PubMed - indexed for MEDLINE]
11.

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

Wang HW, Pasternak JF, Kuo H, Ristic H, Lambert MP, Chromy B, Viola KL, Klein WL, Stine WB, Krafft GA, Trommer BL.

Brain Res. 2002 Jan 11;924(2):133-40.

PMID:
11750898
[PubMed - indexed for MEDLINE]
12.

Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

Jenkins BG, Klivenyi P, Kustermann E, Andreassen OA, Ferrante RJ, Rosen BR, Beal MF.

J Neurochem. 2000 May;74(5):2108-19.

PMID:
10800956
[PubMed - indexed for MEDLINE]
13.

Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

McLaurin J, Golomb R, Jurewicz A, Antel JP, Fraser PE.

J Biol Chem. 2000 Jun 16;275(24):18495-502.

PMID:
10764800
[PubMed - indexed for MEDLINE]
Free Article
14.

Effect of ammonia and methionine sulfoximine on myo-inositol transport in cultured astrocytes.

Isaacks RE, Bender AS, Kim CY, Shi YF, Norenberg MD.

Neurochem Res. 1999 Jan;24(1):51-9.

PMID:
9973237
[PubMed - indexed for MEDLINE]
15.

Identification of a high concentration of scyllo-inositol in the brain of a healthy human subject using 1H- and 13C-NMR.

Seaquist ER, Gruetter R.

Magn Reson Med. 1998 Feb;39(2):313-6.

PMID:
9469716
[PubMed - indexed for MEDLINE]
16.

Magnetic resonance spectroscopic changes in Alzheimer's disease.

Pettegrew JW, Klunk WE, Panchalingam K, McClure RJ, Stanley JA.

Ann N Y Acad Sci. 1997 Sep 26;826:282-306. Review.

PMID:
9329700
[PubMed - indexed for MEDLINE]
17.

The pathogenesis of senile plaques.

Dickson DW.

J Neuropathol Exp Neurol. 1997 Apr;56(4):321-39. Review.

PMID:
9100663
[PubMed - indexed for MEDLINE]
18.

Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice.

Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G.

Science. 1996 Oct 4;274(5284):99-102.

PMID:
8810256
[PubMed - indexed for MEDLINE]
19.

Quantitative 1H and 31P MRS of PCA extracts of postmortem Alzheimer's disease brain.

Klunk WE, Xu C, Panchalingam K, McClure RJ, Pettegrew JW.

Neurobiol Aging. 1996 May-Jun;17(3):349-57.

PMID:
8725895
[PubMed - indexed for MEDLINE]
20.

Identification of Scyllo-inositol in proton NMR spectra of human brain in vivo.

Michaelis T, Helms G, Merboldt KD, Hänicke W, Bruhn H, Frahm J.

NMR Biomed. 1993 Jan-Feb;6(1):105-9.

PMID:
8384468
[PubMed - indexed for MEDLINE]
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