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Results: 1 to 20 of 47

1.

Arrhythmia phenotype in mouse models of human long QT.

Salama G, Baker L, Wolk R, Barhanin J, London B.

J Interv Card Electrophysiol. 2009 Mar;24(2):77-87. doi: 10.1007/s10840-008-9339-6. Epub 2009 Jan 16.

PMID:
19148726
[PubMed - indexed for MEDLINE]
2.

Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality.

Teng GQ, Zhao X, Lees-Miller JP, Quinn FR, Li P, Rancourt DE, London B, Cross JC, Duff HJ.

Circ Res. 2008 Dec 5;103(12):1483-91. doi: 10.1161/CIRCRESAHA.108.177055. Epub 2008 Oct 23.

PMID:
18948620
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome.

Sale H, Wang J, O'Hara TJ, Tester DJ, Phartiyal P, He JQ, Rudy Y, Ackerman MJ, Robertson GA.

Circ Res. 2008 Sep 26;103(7):e81-95. doi: 10.1161/CIRCRESAHA.108.185249. Epub 2008 Sep 5.

PMID:
18776039
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Kv11.1 channel subunit composition includes MinK and varies developmentally in mouse cardiac muscle.

Wang X, Xu R, Abernathey G, Taylor J, Alzghoul MB, Hannon K, Hockerman GH, Pond AL.

Dev Dyn. 2008 Sep;237(9):2430-7. doi: 10.1002/dvdy.21671.

PMID:
18729211
[PubMed - indexed for MEDLINE]
Free Article
5.

Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol.

Balijepalli RC, Delisle BP, Balijepalli SY, Foell JD, Slind JK, Kamp TJ, January CT.

Channels (Austin). 2007 Jul-Aug;1(4):263-72. Epub 2007 Aug 27.

PMID:
18708743
[PubMed - indexed for MEDLINE]
Free Article
6.

Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome.

Brunner M, Peng X, Liu GX, Ren XQ, Ziv O, Choi BR, Mathur R, Hajjiri M, Odening KE, Steinberg E, Folco EJ, Pringa E, Centracchio J, Macharzina RR, Donahay T, Schofield L, Rana N, Kirk M, Mitchell GF, Poppas A, Zehender M, Koren G.

J Clin Invest. 2008 Jun;118(6):2246-59. doi: 10.1172/JCI33578.

PMID:
18464931
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mathematical model of the neonatal mouse ventricular action potential.

Wang LJ, Sobie EA.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2565-75. doi: 10.1152/ajpheart.01376.2007. Epub 2008 Apr 11.

PMID:
18408122
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers.

Horiba M, Muto T, Ueda N, Opthof T, Miwa K, Hojo M, Lee JK, Kamiya K, Kodama I, Yasui K.

Life Sci. 2008 Mar 12;82(11-12):554-60. doi: 10.1016/j.lfs.2007.11.010. Epub 2007 Dec 4.

PMID:
18275974
[PubMed - indexed for MEDLINE]
9.

Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5.

Wu L, Yong SL, Fan C, Ni Y, Yoo S, Zhang T, Zhang X, Obejero-Paz CA, Rho HJ, Ke T, Szafranski P, Jones SW, Chen Q, Wang QK.

J Biol Chem. 2008 Mar 14;283(11):6968-78. doi: 10.1074/jbc.M709721200. Epub 2008 Jan 9.

PMID:
18184654
[PubMed - indexed for MEDLINE]
Free Article
10.

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.

Van Norstrand DW, Valdivia CR, Tester DJ, Ueda K, London B, Makielski JC, Ackerman MJ.

Circulation. 2007 Nov 13;116(20):2253-9. Epub 2007 Oct 29.

PMID:
17967976
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome.

Gong Q, Zhang L, Vincent GM, Horne BD, Zhou Z.

Circulation. 2007 Jul 3;116(1):17-24. Epub 2007 Jun 18.

PMID:
17576861
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Role of neuronal nitric oxide synthase in lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal mouse cardiomyocytes.

Geoghegan-Morphet N, Burger D, Lu X, Sathish V, Peng T, Sims SM, Feng Q.

Cardiovasc Res. 2007 Jul 15;75(2):408-16. Epub 2007 Mar 30. Erratum in: Cardiovasc Res. 2009 Mar 1;81(4):814.

PMID:
17466955
[PubMed - indexed for MEDLINE]
Free Article
13.

Cardiac myocyte cell cycle control in development, disease, and regeneration.

Ahuja P, Sdek P, MacLellan WR.

Physiol Rev. 2007 Apr;87(2):521-44. Review.

PMID:
17429040
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Calcineurin increases cardiac transient outward K+ currents via transcriptional up-regulation of Kv4.2 channel subunits.

Gong N, Bodi I, Zobel C, Schwartz A, Molkentin JD, Backx PH.

J Biol Chem. 2006 Dec 15;281(50):38498-506. Epub 2006 Oct 23.

PMID:
17060317
[PubMed - indexed for MEDLINE]
Free Article
15.

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

Rajamani S, Eckhardt LL, Valdivia CR, Klemens CA, Gillman BM, Anderson CL, Holzem KM, Delisle BP, Anson BD, Makielski JC, January CT.

Br J Pharmacol. 2006 Nov;149(5):481-9. Epub 2006 Sep 11.

PMID:
16967046
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Wild-type and mutant HCN channels in a tandem biological-electronic cardiac pacemaker.

Bucchi A, Plotnikov AN, Shlapakova I, Danilo P Jr, Kryukova Y, Qu J, Lu Z, Liu H, Pan Z, Potapova I, KenKnight B, Girouard S, Cohen IS, Brink PR, Robinson RB, Rosen MR.

Circulation. 2006 Sep 5;114(10):992-9. Epub 2006 Aug 21.

PMID:
16923750
[PubMed - indexed for MEDLINE]
Free Article
17.

Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation.

Balijepalli RC, Foell JD, Hall DD, Hell JW, Kamp TJ.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7500-5. Epub 2006 Apr 28.

PMID:
16648270
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases.

Prud'homme GJ, Glinka Y, Khan AS, Draghia-Akli R.

Curr Gene Ther. 2006 Apr;6(2):243-73. Review.

PMID:
16611045
[PubMed - indexed for MEDLINE]
19.

Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.

Anderson CL, Delisle BP, Anson BD, Kilby JA, Will ML, Tester DJ, Gong Q, Zhou Z, Ackerman MJ, January CT.

Circulation. 2006 Jan 24;113(3):365-73.

PMID:
16432067
[PubMed - indexed for MEDLINE]
Free Article
20.

Dynamic control of hERG/I(Kr) by PKA-mediated interactions with 14-3-3.

Kagan A, McDonald TV.

Novartis Found Symp. 2005;266:75-89; discussion 89-99. Review.

PMID:
16050263
[PubMed - indexed for MEDLINE]

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