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Items: 19

1.

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes.

Eizirik DL, Colli ML, Ortis F.

Nat Rev Endocrinol. 2009 Apr;5(4):219-26. doi: 10.1038/nrendo.2009.21. Review.

PMID:
19352320
2.

Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.

Elagin RB, Balijepalli S, Diacovo MJ, Baekkeskov S, Jaume JC.

J Autoimmun. 2009 Aug;33(1):50-7. doi: 10.1016/j.jaut.2009.02.004. Epub 2009 Mar 16.

3.

GAD treatment and insulin secretion in recent-onset type 1 diabetes.

Ludvigsson J, Faresjö M, Hjorth M, Axelsson S, Chéramy M, Pihl M, Vaarala O, Forsander G, Ivarsson S, Johansson C, Lindh A, Nilsson NO, Aman J, Ortqvist E, Zerhouni P, Casas R.

N Engl J Med. 2008 Oct 30;359(18):1909-20. doi: 10.1056/NEJMoa0804328. Epub 2008 Oct 8.

4.

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.

Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD.

Genome Res. 2008 May;18(5):706-16. doi: 10.1101/gr.074914.107. Epub 2008 Mar 17.

5.

Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications.

Hartman ZC, Appledorn DM, Amalfitano A.

Virus Res. 2008 Mar;132(1-2):1-14. Epub 2007 Nov 26. Review.

6.

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.

Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, Bland RJ, Young D, Strybing K, Eidelberg D, During MJ.

Lancet. 2007 Jun 23;369(9579):2097-105.

PMID:
17586305
7.

A Fifth Allelomorph in the Agouti Series of the House Mouse.

Dunn LC.

Proc Natl Acad Sci U S A. 1928 Oct;14(10):816-9. No abstract available.

8.

Genetic obesity unmasks nonlinear interactions between murine type 2 diabetes susceptibility loci.

Stoehr JP, Nadler ST, Schueler KL, Rabaglia ME, Yandell BS, Metz SA, Attie AD.

Diabetes. 2000 Nov;49(11):1946-54.

PMID:
11078464
9.

Does GAD have a unique role in triggering IDDM?

Baekkeskov S, Kanaani J, Jaume JC, Kash S.

J Autoimmun. 2000 Nov;15(3):279-86. Review. No abstract available.

PMID:
11040068
10.

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.

Shi Y, Kanaani J, Menard-Rose V, Ma YH, Chang PY, Hanahan D, Tobin A, Grodsky G, Baekkeskov S.

Am J Physiol Endocrinol Metab. 2000 Sep;279(3):E684-94.

11.

Induction of insulitis by glutamic acid decarboxylase peptide-specific and HLA-DQ8-restricted CD4(+) T cells from human DQ transgenic mice.

Wen L, Wong FS, Burkly L, Altieri M, Mamalaki C, Kioussis D, Flavell RA, Sherwin RS.

J Clin Invest. 1998 Sep 1;102(5):947-57. Erratum in: J Clin Invest 1998 Oct 1;102(7):following 1463.

12.

Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.

Mehrabian M, Wen PZ, Fisler J, Davis RC, Lusis AJ.

J Clin Invest. 1998 Jun 1;101(11):2485-96.

13.

Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase.

Hagopian WA, Michelsen B, Karlsen AE, Larsen F, Moody A, Grubin CE, Rowe R, Petersen J, McEvoy R, Lernmark A.

Diabetes. 1993 Apr;42(4):631-6.

PMID:
8454115
14.

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

Kim J, Richter W, Aanstoot HJ, Shi Y, Fu Q, Rajotte R, Warnock G, Baekkeskov S.

Diabetes. 1993 Dec;42(12):1799-808.

PMID:
8243826
15.

Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases.

Rabin DU, Pleasic SM, Shapiro JA, Yoo-Warren H, Oles J, Hicks JM, Goldstein DE, Rae PM.

J Immunol. 1994 Mar 15;152(6):3183-8.

PMID:
8144912
17.

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.

Todd JA, Bell JI, McDevitt HO.

Nature. 1987 Oct 15-21;329(6140):599-604.

PMID:
3309680
18.

Distinct antibody specificities to a 64-kD islet cell antigen in type 1 diabetes as revealed by trypsin treatment.

Christie MR, Vohra G, Champagne P, Daneman D, Delovitch TL.

J Exp Med. 1990 Sep 1;172(3):789-94.

19.

Molecular characterization of the mouse agouti locus.

Bultman SJ, Michaud EJ, Woychik RP.

Cell. 1992 Dec 24;71(7):1195-204.

PMID:
1473152
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