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Items: 1 to 20 of 29

1.

Advances in individual prediction of methotrexate toxicity: a review.

Schmiegelow K.

Br J Haematol. 2009 Sep;146(5):489-503. doi: 10.1111/j.1365-2141.2009.07765.x. Epub 2009 Jun 15. Review.

PMID:
19538530
2.

Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia.

de Jonge R, Tissing WJ, Hooijberg JH, Jansen G, Kaspers GJ, Lindemans J, Peters GJ, Pieters R.

Blood. 2009 Mar 5;113(10):2284-9. doi: 10.1182/blood-2008-07-165928. Epub 2008 Nov 19.

3.

Pharmacogenetics influence treatment efficacy in childhood acute lymphoblastic leukemia.

Davidsen ML, Dalhoff K, Schmiegelow K.

J Pediatr Hematol Oncol. 2008 Nov;30(11):831-49. doi: 10.1097/MPH.0b013e3181868570. Review.

PMID:
18989161
4.

Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

Schmiegelow K, Forestier E, Kristinsson J, Söderhäll S, Vettenranta K, Weinshilboum R, Wesenberg F; Nordic Society of Paediatric Haematology and Oncology.

Leukemia. 2009 Mar;23(3):557-64. doi: 10.1038/leu.2008.316. Epub 2008 Nov 6.

5.

Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells.

Baslund B, Gregers J, Nielsen CH.

Rheumatology (Oxford). 2008 Apr;47(4):451-3. doi: 10.1093/rheumatology/ken073. Epub 2008 Mar 3.

6.

Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival.

Forestier E, Heyman M, Andersen MK, Autio K, Blennow E, Borgström G, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kerndrup G, Nordgren A, Rosenquist R, Swolin B, Johansson B; Nordic Society of Paediatric Haematology, Oncology (NOPHO); Swedish Cytogenetic Leukaemia Study Group (SCLSG); NOPHO Leukaemia Cytogenetic Study Group (NLCSG).

Br J Haematol. 2008 Mar;140(6):665-72. doi: 10.1111/j.1365-2141.2008.06980.x. Epub 2008 Feb 1.

PMID:
18241254
7.

Reduced folate carrier-1 80G>A polymorphism affects methotrexate treatment outcome in rheumatoid arthritis.

Drozdzik M, Rudas T, Pawlik A, Gornik W, Kurzawski M, Herczynska M.

Pharmacogenomics J. 2007 Dec;7(6):404-7. Epub 2007 Feb 27.

PMID:
17325736
8.

High leucovorin doses during high-dose methotrexate treatment may reduce the cure rate in childhood acute lymphoblastic leukemia.

Skärby TV, Anderson H, Heldrup J, Kanerva JA, Seidel H, Schmiegelow K; Nordic Society of Paediatric Haematology and Oncology (NOPHO).

Leukemia. 2006 Nov;20(11):1955-62. Epub 2006 Sep 21.

PMID:
16990760
9.

Pharmacogenetics of outcome in children with acute lymphoblastic leukemia.

Rocha JC, Cheng C, Liu W, Kishi S, Das S, Cook EH, Sandlund JT, Rubnitz J, Ribeiro R, Campana D, Pui CH, Evans WE, Relling MV.

Blood. 2005 Jun 15;105(12):4752-8. Epub 2005 Feb 15.

11.

Down syndrome, drug metabolism and chromosome 21.

Taub JW, Ge Y.

Pediatr Blood Cancer. 2005 Jan;44(1):33-9. Review.

PMID:
15390307
12.

Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.

Levy AS, Sather HN, Steinherz PG, Sowers R, La M, Moscow JA, Gaynon PS, Uckun FM, Bertino JR, Gorlick R; Children's Cancer Group Study.

J Pediatr Hematol Oncol. 2003 Sep;25(9):688-95.

PMID:
12972803
13.
15.

Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers.

Whetstine JR, Gifford AJ, Witt T, Liu XY, Flatley RM, Norris M, Haber M, Taub JW, Ravindranath Y, Matherly LH.

Clin Cancer Res. 2001 Nov;7(11):3416-22.

16.

Molecular and cellular biology of the human reduced folate carrier.

Matherly LH.

Prog Nucleic Acid Res Mol Biol. 2001;67:131-62. Review.

PMID:
11525381
17.
18.

Improving outcome through two decades in childhood ALL in the Nordic countries: the impact of high-dose methotrexate in the reduction of CNS irradiation. Nordic Society of Pediatric Haematology and Oncology (NOPHO).

Gustafsson G, Schmiegelow K, Forestier E, Clausen N, Glomstein A, Jonmundsson G, Mellander L, Mäkipernaa A, Nygaard R, Saarinen-Pihkala UM.

Leukemia. 2000 Dec;14(12):2267-75.

PMID:
11187918
19.

A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia.

Chango A, Emery-Fillon N, de Courcy GP, Lambert D, Pfister M, Rosenblatt DS, Nicolas JP.

Mol Genet Metab. 2000 Aug;70(4):310-5.

PMID:
10993718
20.

Molecular and cellular correlates of methotrexate response in childhood acute lymphoblastic leukemia.

Matherly LH, Taub JW.

Leuk Lymphoma. 1999 Sep;35(1-2):1-20. Review.

PMID:
10512159
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