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Items: 1 to 20 of 35

1.

sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons.

Herrera Y, Katnik C, Rodriguez JD, Hall AA, Willing A, Pennypacker KR, Cuevas J.

J Pharmacol Exp Ther. 2008 Nov;327(2):491-502. doi: 10.1124/jpet.108.143974. Epub 2008 Aug 22.

2.

Future of neuroprotection for acute stroke: in the aftermath of the SAINT trials.

Savitz SI, Fisher M.

Ann Neurol. 2007 May;61(5):396-402. Review.

PMID:
17420989
4.

Translating animal research into clinical benefit.

Hackam DG.

BMJ. 2007 Jan 27;334(7586):163-4. No abstract available.

5.

Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia.

Pignataro G, Simon RP, Xiong ZG.

Brain. 2007 Jan;130(Pt 1):151-8. Epub 2006 Nov 17.

6.

Acid-sensing ion channels: advances, questions and therapeutic opportunities.

Wemmie JA, Price MP, Welsh MJ.

Trends Neurosci. 2006 Oct;29(10):578-86. Epub 2006 Aug 7. Review.

PMID:
16891000
7.

Modulation of acid-sensing ion channel currents, acid-induced increase of intracellular Ca2+, and acidosis-mediated neuronal injury by intracellular pH.

Wang WZ, Chu XP, Li MH, Seeds J, Simon RP, Xiong ZG.

J Biol Chem. 2006 Sep 29;281(39):29369-78. Epub 2006 Aug 1.

8.

Thrombolysis 2004: the good, the bad, and the ugly.

Caplan LR.

Rev Neurol Dis. 2004 Winter;1(1):16-26. Review.

PMID:
16397447
9.

Coupling between NMDA receptor and acid-sensing ion channel contributes to ischemic neuronal death.

Gao J, Duan B, Wang DG, Deng XH, Zhang GY, Xu L, Xu TL.

Neuron. 2005 Nov 23;48(4):635-46.

10.

Limiting stroke-induced damage by targeting an acid channel.

Benveniste M, Dingledine R.

N Engl J Med. 2005 Jan 6;352(1):85-6. No abstract available.

PMID:
15635119
11.

Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels.

Chu XP, Wemmie JA, Wang WZ, Zhu XM, Saugstad JA, Price MP, Simon RP, Xiong ZG.

J Neurosci. 2004 Oct 6;24(40):8678-89.

12.

Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke.

Wang X, Tsuji K, Lee SR, Ning M, Furie KL, Buchan AM, Lo EH.

Stroke. 2004 Nov;35(11 Suppl 1):2726-30. Epub 2004 Sep 30. Review.

13.

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDonald JF, Wemmie JA, Price MP, Welsh MJ, Simon RP.

Cell. 2004 Sep 17;118(6):687-98.

14.

Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a.

Yermolaieva O, Leonard AS, Schnizler MK, Abboud FM, Welsh MJ.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6752-7. Epub 2004 Apr 13.

15.

The rise and fall of NMDA antagonists for ischemic stroke.

Hoyte L, Barber PA, Buchan AM, Hill MD.

Curr Mol Med. 2004 Mar;4(2):131-6. Review.

PMID:
15032709
16.

Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons.

Askwith CC, Wemmie JA, Price MP, Rokhlina T, Welsh MJ.

J Biol Chem. 2004 Apr 30;279(18):18296-305. Epub 2004 Feb 11.

17.

The ASICs: signaling molecules? Modulators?

Krishtal O.

Trends Neurosci. 2003 Sep;26(9):477-83. Review.

PMID:
12948658
18.

Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

Ikonomidou C, Turski L.

Lancet Neurol. 2002 Oct;1(6):383-6. Review.

PMID:
12849400
19.

The acid-activated ion channel ASIC contributes to synaptic plasticity, learning, and memory.

Wemmie JA, Chen J, Askwith CC, Hruska-Hageman AM, Price MP, Nolan BC, Yoder PG, Lamani E, Hoshi T, Freeman JH Jr, Welsh MJ.

Neuron. 2002 Apr 25;34(3):463-77.

20.

Protons at the gate: DEG/ENaC ion channels help us feel and remember.

Bianchi L, Driscoll M.

Neuron. 2002 Apr 25;34(3):337-40. Review.

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