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Results: 1 to 20 of 50

1.

Human caspases: activation, specificity, and regulation.

Pop C, Salvesen GS.

J Biol Chem. 2009 Aug 14;284(33):21777-81. doi: 10.1074/jbc.R800084200. Epub 2009 May 26. Review.

PMID:
19473994
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Current affairs in quantitative targeted proteomics: multiple reaction monitoring-mass spectrometry.

Yocum AK, Chinnaiyan AM.

Brief Funct Genomic Proteomic. 2009 Mar;8(2):145-57. doi: 10.1093/bfgp/eln056. Epub 2009 Mar 11. Review.

PMID:
19279071
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Two-state selection of conformation-specific antibodies.

Gao J, Sidhu SS, Wells JA.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3071-6. doi: 10.1073/pnas.0812952106. Epub 2009 Feb 10.

PMID:
19208804
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H, Planyavsky M, Bilban M, Colinge J, Bennett KL, Superti-Furga G.

Nat Immunol. 2009 Mar;10(3):266-72. doi: 10.1038/ni.1702. Epub 2009 Jan 21.

PMID:
19158679
[PubMed - indexed for MEDLINE]
5.

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.

Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES.

Nature. 2009 Mar 26;458(7237):509-13. doi: 10.1038/nature07710. Epub 2009 Jan 21.

PMID:
19158676
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.

Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA.

Nature. 2009 Mar 26;458(7237):514-8. doi: 10.1038/nature07725. Epub 2009 Jan 21.

PMID:
19158675
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA.

Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, Hardy LL, Garceau V, Sweet MJ, Ross IL, Hume DA, Stacey KJ.

Science. 2009 Feb 20;323(5917):1057-60. doi: 10.1126/science.1169841. Epub 2009 Jan 8.

PMID:
19131592
[PubMed - indexed for MEDLINE]
Free Article
8.

Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages.

Nour AM, Yeung YG, Santambrogio L, Boyden ED, Stanley ER, Brojatsch J.

Infect Immun. 2009 Mar;77(3):1262-71. doi: 10.1128/IAI.01032-08. Epub 2009 Jan 5.

PMID:
19124602
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Mechanisms of regulated unconventional protein secretion.

Nickel W, Rabouille C.

Nat Rev Mol Cell Biol. 2009 Feb;10(2):148-55. doi: 10.1038/nrm2617. Epub 2008 Dec 24. Review. Erratum in: Nat Rev Mol Cell Biol. 2009 Mar;10(3):234.

PMID:
19122676
[PubMed - indexed for MEDLINE]
10.

Global mapping of the topography and magnitude of proteolytic events in apoptosis.

Dix MM, Simon GM, Cravatt BF.

Cell. 2008 Aug 22;134(4):679-91. doi: 10.1016/j.cell.2008.06.038.

PMID:
18724940
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Executioner caspase-3 and caspase-7 are functionally distinct proteases.

Walsh JG, Cullen SP, Sheridan C, Lüthi AU, Gerner C, Martin SJ.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12815-9. doi: 10.1073/pnas.0707715105. Epub 2008 Aug 22.

PMID:
18723680
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini.

Mahrus S, Trinidad JC, Barkan DT, Sali A, Burlingame AL, Wells JA.

Cell. 2008 Sep 5;134(5):866-76. doi: 10.1016/j.cell.2008.08.012. Epub 2008 Aug 21.

PMID:
18722006
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.

Lamkanfi M, Kanneganti TD, Van Damme P, Vanden Berghe T, Vanoverberghe I, Vandekerckhove J, Vandenabeele P, Gevaert K, Núñez G.

Mol Cell Proteomics. 2008 Dec;7(12):2350-63. doi: 10.1074/mcp.M800132-MCP200. Epub 2008 Jul 30.

PMID:
18667412
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome.

Doucet A, Butler GS, Rodríguez D, Prudova A, Overall CM.

Mol Cell Proteomics. 2008 Oct;7(10):1925-51. doi: 10.1074/mcp.R800012-MCP200. Epub 2008 Jul 2. Review.

PMID:
18596063
[PubMed - indexed for MEDLINE]
Free Article
15.

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment.

Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, Masters SL, Gumucio DL, Shoham NG, Kastner DL.

Blood. 2008 Sep 1;112(5):1794-803. doi: 10.1182/blood-2008-01-134932. Epub 2008 Jun 24.

PMID:
18577712
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The Nalp3 inflammasome is essential for the development of silicosis.

Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9035-40. doi: 10.1073/pnas.0803933105. Epub 2008 Jun 24.

PMID:
18577586
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms.

Fink SL, Bergsbaken T, Cookson BT.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4312-7. doi: 10.1073/pnas.0707370105. Epub 2008 Mar 12.

PMID:
18337499
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The inflammasome: a danger sensing complex triggering innate immunity.

Pétrilli V, Dostert C, Muruve DA, Tschopp J.

Curr Opin Immunol. 2007 Dec;19(6):615-22. Epub 2007 Oct 30. Review.

PMID:
17977705
[PubMed - indexed for MEDLINE]
19.

Protease research in the era of systems biology.

auf dem Keller U, Doucet A, Overall CM.

Biol Chem. 2007 Nov;388(11):1159-62. Review.

PMID:
17976008
[PubMed - indexed for MEDLINE]
20.

Overlapping cleavage motif selectivity of caspases: implications for analysis of apoptotic pathways.

McStay GP, Salvesen GS, Green DR.

Cell Death Differ. 2008 Feb;15(2):322-31. Epub 2007 Nov 2.

PMID:
17975551
[PubMed - indexed for MEDLINE]
Free Article

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