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Results: 1 to 20 of 78

1.

Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain.

Wang HY, Stucky A, Liu J, Shen C, Trocme-Thibierge C, Morain P.

J Neurosci. 2009 Sep 2;29(35):10961-73. doi: 10.1523/JNEUROSCI.6088-08.2009.

PMID:
19726654
[PubMed - indexed for MEDLINE]
Free Article
2.

Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease.

Dziewczapolski G, Glogowski CM, Masliah E, Heinemann SF.

J Neurosci. 2009 Jul 8;29(27):8805-15. doi: 10.1523/JNEUROSCI.6159-08.2009.

PMID:
19587288
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction.

Tomic JL, Pensalfini A, Head E, Glabe CG.

Neurobiol Dis. 2009 Sep;35(3):352-8. doi: 10.1016/j.nbd.2009.05.024. Epub 2009 Jun 10.

PMID:
19523517
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.

Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST.

Arch Neurol. 2009 May;66(5):646-51. doi: 10.1001/archneurol.2009.46.

PMID:
19433665
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structural characterization of a soluble amyloid beta-peptide oligomer.

Yu L, Edalji R, Harlan JE, Holzman TF, Lopez AP, Labkovsky B, Hillen H, Barghorn S, Ebert U, Richardson PL, Miesbauer L, Solomon L, Bartley D, Walter K, Johnson RW, Hajduk PJ, Olejniczak ET.

Biochemistry. 2009 Mar 10;48(9):1870-7. doi: 10.1021/bi802046n.

PMID:
19216516
[PubMed - indexed for MEDLINE]
6.

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition.

Taglialatela G, Hogan D, Zhang WR, Dineley KT.

Behav Brain Res. 2009 Jun 8;200(1):95-9. doi: 10.1016/j.bbr.2008.12.034. Epub 2009 Jan 8.

PMID:
19162087
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Decreased acetylcholine release is correlated to memory impairment in the Tg2576 transgenic mouse model of Alzheimer's disease.

Watanabe T, Yamagata N, Takasaki K, Sano K, Hayakawa K, Katsurabayashi S, Egashira N, Mishima K, Iwasaki K, Fujiwara M.

Brain Res. 2009 Jan 16;1249:222-8. doi: 10.1016/j.brainres.2008.10.029. Epub 2008 Oct 28.

PMID:
18996097
[PubMed - indexed for MEDLINE]
8.

Structural classification of toxic amyloid oligomers.

Glabe CG.

J Biol Chem. 2008 Oct 31;283(44):29639-43. doi: 10.1074/jbc.R800016200. Epub 2008 Aug 22. Review.

PMID:
18723507
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Alpha7 nicotinic acetylcholine receptor expression by vascular smooth muscle cells facilitates the deposition of Abeta peptides and promotes cerebrovascular amyloid angiopathy.

Clifford PM, Siu G, Kosciuk M, Levin EC, Venkataraman V, D'Andrea MR, Nagele RG.

Brain Res. 2008 Oct 9;1234:158-71. doi: 10.1016/j.brainres.2008.07.092. Epub 2008 Aug 3.

PMID:
18708033
[PubMed - indexed for MEDLINE]
10.

The nicotinic alpha7 acetylcholine receptor agonist ssr180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta1-42.

Søderman A, Thomsen MS, Hansen HH, Nielsen EØ, Jensen MS, West MJ, Mikkelsen JD.

Brain Res. 2008 Aug 28;1227:240-7. doi: 10.1016/j.brainres.2008.06.062. Epub 2008 Jun 25.

PMID:
18619425
[PubMed - indexed for MEDLINE]
11.

Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures.

Poling A, Morgan-Paisley K, Panos JJ, Kim EM, O'Hare E, Cleary JP, Lesné S, Ashe KH, Porritt M, Baker LE.

Behav Brain Res. 2008 Nov 21;193(2):230-4. doi: 10.1016/j.bbr.2008.06.001. Epub 2008 Jun 8.

PMID:
18585407
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval.

Winters BD, Saksida LM, Bussey TJ.

Neurosci Biobehav Rev. 2008 Jul;32(5):1055-70. doi: 10.1016/j.neubiorev.2008.04.004. Epub 2008 Apr 24. Review.

PMID:
18499253
[PubMed - indexed for MEDLINE]
13.

Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.

Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ.

Arch Neurol. 2007 Dec;64(12):1771-6.

PMID:
18071042
[PubMed - indexed for MEDLINE]
14.

Beta-amyloid modulation of synaptic transmission and plasticity.

Venkitaramani DV, Chin J, Netzer WJ, Gouras GK, Lesne S, Malinow R, Lombroso PJ.

J Neurosci. 2007 Oct 31;27(44):11832-7. Review. No abstract available.

PMID:
17978019
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers.

Kayed R, Head E, Sarsoza F, Saing T, Cotman CW, Necula M, Margol L, Wu J, Breydo L, Thompson JL, Rasool S, Gurlo T, Butler P, Glabe CG.

Mol Neurodegener. 2007 Sep 26;2:18.

PMID:
17897471
[PubMed]
Free PMC Article
16.

The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.

Ren K, King MA, Liu J, Siemann J, Altman M, Meyers C, Hughes JA, Meyer EM.

Neuroscience. 2007 Aug 10;148(1):230-7. Epub 2007 Jul 20.

PMID:
17640819
[PubMed - indexed for MEDLINE]
17.

Beta-amyloid peptide--nicotinic acetylcholine receptor interaction: the two faces of health and disease.

Dineley KT.

Front Biosci. 2007 Sep 1;12:5030-8. Review.

PMID:
17569627
[PubMed - indexed for MEDLINE]
18.

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice.

Dineley KT, Hogan D, Zhang WR, Taglialatela G.

Neurobiol Learn Mem. 2007 Sep;88(2):217-24. Epub 2007 May 22.

PMID:
17521929
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.

Wilcock DM, Gordon MN, Morgan D.

Nat Protoc. 2006;1(3):1591-5.

PMID:
17406451
[PubMed - indexed for MEDLINE]
20.

Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease.

Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL.

J Neurosci. 2007 Jan 24;27(4):796-807.

PMID:
17251419
[PubMed - indexed for MEDLINE]
Free Article

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