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Items: 1 to 20 of 107

1.

The increasing complexity of the cancer stem cell paradigm.

Rosen JM, Jordan CT.

Science. 2009 Jun 26;324(5935):1670-3. doi: 10.1126/science.1171837. Review.

2.

Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis.

Chu PY, Huang LY, Hsu CH, Liang CC, Guan JL, Hung TH, Shen TL.

J Biol Chem. 2009 Jul 24;284(30):20215-26. doi: 10.1074/jbc.M109.018259. Epub 2009 May 27.

3.

Principles of cancer therapy: oncogene and non-oncogene addiction.

Luo J, Solimini NL, Elledge SJ.

Cell. 2009 Mar 6;136(5):823-37. doi: 10.1016/j.cell.2009.02.024. Erratum in: Cell. 2009 Aug 21;138(4):807.

4.

Association of reactive oxygen species levels and radioresistance in cancer stem cells.

Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF.

Nature. 2009 Apr 9;458(7239):780-3. doi: 10.1038/nature07733.

5.

Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

Pylayeva Y, Gillen KM, Gerald W, Beggs HE, Reichardt LF, Giancotti FG.

J Clin Invest. 2009 Feb;119(2):252-66. doi: 10.1172/JCI37160. Epub 2009 Jan 19.

6.

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells.

Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL.

Cancer Res. 2009 Jan 15;69(2):466-74. doi: 10.1158/0008-5472.CAN-08-3078.

7.

Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.

Provenzano PP, Inman DR, Eliceiri KW, Beggs HE, Keely PJ.

Am J Pathol. 2008 Nov;173(5):1551-65. doi: 10.2353/ajpath.2008.080308. Epub 2008 Oct 9.

8.

Cancer immunology.

Finn OJ.

N Engl J Med. 2008 Jun 19;358(25):2704-15. doi: 10.1056/NEJMra072739. Review. No abstract available.

PMID:
18565863
9.

Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells.

Taddei I, Deugnier MA, Faraldo MM, Petit V, Bouvard D, Medina D, Fässler R, Thiery JP, Glukhova MA.

Nat Cell Biol. 2008 Jun;10(6):716-22. doi: 10.1038/ncb1734. Epub 2008 May 11.

10.

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy.

Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC.

J Natl Cancer Inst. 2008 May 7;100(9):672-9. doi: 10.1093/jnci/djn123. Epub 2008 Apr 29.

11.

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling.

Malanchi I, Peinado H, Kassen D, Hussenet T, Metzger D, Chambon P, Huber M, Hohl D, Cano A, Birchmeier W, Huelsken J.

Nature. 2008 Apr 3;452(7187):650-3. doi: 10.1038/nature06835.

PMID:
18385740
12.

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model.

Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z.

Cancer Cell. 2008 Feb;13(2):141-52. doi: 10.1016/j.ccr.2008.01.011.

13.

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression.

Lahlou H, Sanguin-Gendreau V, Zuo D, Cardiff RD, McLean GW, Frame MC, Muller WJ.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20302-7. Epub 2007 Dec 3.

14.

Adaptive immunity maintains occult cancer in an equilibrium state.

Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, Smyth MJ, Schreiber RD.

Nature. 2007 Dec 6;450(7171):903-7. Epub 2007 Nov 18.

PMID:
18026089
15.

Spatial and temporal regulation of focal adhesion kinase activity in living cells.

Cai X, Lietha D, Ceccarelli DF, Karginov AV, Rajfur Z, Jacobson K, Hahn KM, Eck MJ, Schaller MD.

Mol Cell Biol. 2008 Jan;28(1):201-14. Epub 2007 Oct 29.

16.

Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis.

Stingl J, Caldas C.

Nat Rev Cancer. 2007 Oct;7(10):791-9. Review.

PMID:
17851544
17.

Focal adhesion kinase and p53 signaling in cancer cells.

Golubovskaya VM, Cance WG.

Int Rev Cytol. 2007;263:103-53. Review.

PMID:
17725966
18.

Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex.

Serrels B, Serrels A, Brunton VG, Holt M, McLean GW, Gray CH, Jones GE, Frame MC.

Nat Cell Biol. 2007 Sep;9(9):1046-56. Epub 2007 Aug 26.

PMID:
17721515
19.

Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland.

Nagy T, Wei H, Shen TL, Peng X, Liang CC, Gan B, Guan JL.

J Biol Chem. 2007 Oct 26;282(43):31766-76. Epub 2007 Aug 23.

20.

Structural basis for the autoinhibition of focal adhesion kinase.

Lietha D, Cai X, Ceccarelli DF, Li Y, Schaller MD, Eck MJ.

Cell. 2007 Jun 15;129(6):1177-87.

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