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Results: 1 to 20 of 28

1.

Continuous quinacrine treatment results in the formation of drug-resistant prions.

Ghaemmaghami S, Ahn M, Lessard P, Giles K, Legname G, DeArmond SJ, Prusiner SB.

PLoS Pathog. 2009 Nov;5(11):e1000673. doi: 10.1371/journal.ppat.1000673. Epub 2009 Nov 26.

PMID:
19956709
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

De novo generation of infectious prions in vitro produces a new disease phenotype.

Barria MA, Mukherjee A, Gonzalez-Romero D, Morales R, Soto C.

PLoS Pathog. 2009 May;5(5):e1000421. doi: 10.1371/journal.ppat.1000421. Epub 2009 May 15. Erratum in: PLoS Pathog. 2013 Mar;9(3). doi:10.1371/annotation/4b55946a-edb5-4feb-aeb5-2ee160394d17.

PMID:
19436715
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Prion strain discrimination in cell culture: the cell panel assay.

Mahal SP, Baker CA, Demczyk CA, Smith EW, Julius C, Weissmann C.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20908-13. Epub 2007 Dec 11.

PMID:
18077360
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A general model of prion strains and their pathogenicity.

Collinge J, Clarke AR.

Science. 2007 Nov 9;318(5852):930-6. Review.

PMID:
17991853
[PubMed - indexed for MEDLINE]
5.

Molecular profiling of ovine prion diseases by using thermolysin-resistant PrPSc and endogenous C2 PrP fragments.

Owen JP, Rees HC, Maddison BC, Terry LA, Thorne L, Jackman R, Whitelam GC, Gough KC.

J Virol. 2007 Oct;81(19):10532-9. Epub 2007 Jul 25.

PMID:
17652380
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.

Legname G, Nguyen HO, Peretz D, Cohen FE, DeArmond SJ, Prusiner SB.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19105-10. Epub 2006 Dec 1.

PMID:
17142317
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Biological and biochemical characteristics of prion strains conserved in persistently infected cell cultures.

Arima K, Nishida N, Sakaguchi S, Shigematsu K, Atarashi R, Yamaguchi N, Yoshikawa D, Yoon J, Watanabe K, Kobayashi N, Mouillet-Richard S, Lehmann S, Katamine S.

J Virol. 2005 Jun;79(11):7104-12.

PMID:
15890950
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Two Creutzfeldt-Jakob disease agents reproduce prion protein-independent identities in cell cultures.

Arjona A, Simarro L, Islinger F, Nishida N, Manuelidis L.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8768-73. Epub 2004 May 25.

PMID:
15161970
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions.

Klöhn PC, Stoltze L, Flechsig E, Enari M, Weissmann C.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11666-71. Epub 2003 Sep 22.

PMID:
14504404
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A change in the conformation of prions accompanies the emergence of a new prion strain.

Peretz D, Williamson RA, Legname G, Matsunaga Y, Vergara J, Burton DR, DeArmond SJ, Prusiner SB, Scott MR.

Neuron. 2002 Jun 13;34(6):921-32.

PMID:
12086640
[PubMed - indexed for MEDLINE]
Free Article
11.

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay.

Wadsworth JD, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J.

Lancet. 2001 Jul 21;358(9277):171-80.

PMID:
11476832
[PubMed - indexed for MEDLINE]
12.

Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding.

Saborio GP, Permanne B, Soto C.

Nature. 2001 Jun 14;411(6839):810-3.

PMID:
11459061
[PubMed - indexed for MEDLINE]
13.

Strain-specified relative conformational stability of the scrapie prion protein.

Peretz D, Scott MR, Groth D, Williamson RA, Burton DR, Cohen FE, Prusiner SB.

Protein Sci. 2001 Apr;10(4):854-63.

PMID:
11274476
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Methods for studying prion protein (PrP) metabolism and the formation of protease-resistant PrP in cell culture and cell-free systems. An update.

Caughey B, Raymond GJ, Priola SA, Kocisko DA, Race RE, Bessen RA, Lansbury PT Jr, Chesebro B.

Mol Biotechnol. 1999 Nov;13(1):45-55.

PMID:
10934521
[PubMed - indexed for MEDLINE]
16.

Species barrier in prion diseases: a kinetic interpretation based on the conformational adaptation of the prion protein.

Kellershohn N, Laurent M.

Biochem J. 1998 Sep 15;334 ( Pt 3):539-45.

PMID:
9729459
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease.

Hilton DA, Fathers E, Edwards P, Ironside JW, Zajicek J.

Lancet. 1998 Aug 29;352(9129):703-4. No abstract available.

PMID:
9728989
[PubMed - indexed for MEDLINE]
18.

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity.

Telling GC, Parchi P, DeArmond SJ, Cortelli P, Montagna P, Gabizon R, Mastrianni J, Lugaresi E, Gambetti P, Prusiner SB.

Science. 1996 Dec 20;274(5295):2079-82.

PMID:
8953038
[PubMed - indexed for MEDLINE]
19.

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

Collinge J, Sidle KC, Meads J, Ironside J, Hill AF.

Nature. 1996 Oct 24;383(6602):685-90.

PMID:
8878476
[PubMed - indexed for MEDLINE]
20.

On the nature of virus quasispecies.

Eigen M.

Trends Microbiol. 1996 Jun;4(6):216-8. No abstract available.

PMID:
8795155
[PubMed - indexed for MEDLINE]

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