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Results: 1 to 20 of 30

1.

Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds.

Kim HS, Fay JC.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19387-91. Epub 2007 Nov 27.

PMID:
18042712
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identifying genetic variants that contribute to chemotherapy-induced cytotoxicity.

Hartford CM, Dolan ME.

Pharmacogenomics. 2007 Sep;8(9):1159-68. Review.

PMID:
17924831
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Translation of pharmacogenetics into clinically relevant testing modalities.

Baudhuin LM, Langman LJ, O'Kane DJ.

Clin Pharmacol Ther. 2007 Oct;82(4):373-6. Review.

PMID:
17851577
[PubMed - indexed for MEDLINE]
4.

The effect of cytochrome P450 metabolism on drug response, interactions, and adverse effects.

Lynch T, Price A.

Am Fam Physician. 2007 Aug 1;76(3):391-6. Review.

PMID:
17708140
[PubMed - indexed for MEDLINE]
Free Article
5.

Translating pharmacogenomics: challenges on the road to the clinic.

Swen JJ, Huizinga TW, Gelderblom H, de Vries EG, Assendelft WJ, Kirchheiner J, Guchelaar HJ.

PLoS Med. 2007 Aug;4(8):e209. Review.

PMID:
17696640
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pharmacogenomics in drug-metabolizing enzymes catalyzing anticancer drugs for personalized cancer chemotherapy.

Fujita K, Sasaki Y.

Curr Drug Metab. 2007 Aug;8(6):554-62. Review.

PMID:
17691917
[PubMed - indexed for MEDLINE]
7.

Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance.

Lo HW, Ali-Osman F.

Curr Opin Pharmacol. 2007 Aug;7(4):367-74. Epub 2007 Aug 6. Review.

PMID:
17681492
[PubMed - indexed for MEDLINE]
8.

A pharmacogenomics primer.

Court MH.

J Clin Pharmacol. 2007 Sep;47(9):1087-103. Epub 2007 Jul 30. Review.

PMID:
17664254
[PubMed - indexed for MEDLINE]
9.

Recent development in pharmacogenomics: from candidate genes to genome-wide association studies.

Grant SF, Hakonarson H.

Expert Rev Mol Diagn. 2007 Jul;7(4):371-93. Review.

PMID:
17620046
[PubMed - indexed for MEDLINE]
10.

Promises of biomarkers in drug development--a reality check.

Marrer E, Dieterle F.

Chem Biol Drug Des. 2007 Jun;69(6):381-94. Review.

PMID:
17581232
[PubMed - indexed for MEDLINE]
11.

A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.

Huang RS, Duan S, Bleibel WK, Kistner EO, Zhang W, Clark TA, Chen TX, Schweitzer AC, Blume JE, Cox NJ, Dolan ME.

Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9758-63. Epub 2007 May 30.

PMID:
17537913
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome-wide screening of loci associated with drug resistance to 5-fluorouracil-based drugs.

Ooyama A, Okayama Y, Takechi T, Sugimoto Y, Oka T, Fukushima M.

Cancer Sci. 2007 Apr;98(4):577-83.

PMID:
17425594
[PubMed - indexed for MEDLINE]
13.

Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study.

Shankavaram UT, Reinhold WC, Nishizuka S, Major S, Morita D, Chary KK, Reimers MA, Scherf U, Kahn A, Dolginow D, Cossman J, Kaldjian EP, Scudiero DA, Petricoin E, Liotta L, Lee JK, Weinstein JN.

Mol Cancer Ther. 2007 Mar;6(3):820-32. Epub 2007 Mar 5.

PMID:
17339364
[PubMed - indexed for MEDLINE]
Free Article
14.

Genetic basis of individual differences in the response to small-molecule drugs in yeast.

Perlstein EO, Ruderfer DM, Roberts DC, Schreiber SL, Kruglyak L.

Nat Genet. 2007 Apr;39(4):496-502. Epub 2007 Mar 4.

PMID:
17334364
[PubMed - indexed for MEDLINE]
15.

Pharmacogenetics/genomics of membrane transporters in cancer chemotherapy.

Huang Y.

Cancer Metastasis Rev. 2007 Mar;26(1):183-201. Review.

PMID:
17323126
[PubMed - indexed for MEDLINE]
16.

Identification of molecular determinants of tumor sensitivity and resistance to anticancer drugs.

Quintieri L, Fantin M, Vizler C.

Adv Exp Med Biol. 2007;593:95-104. Review.

PMID:
17265720
[PubMed - indexed for MEDLINE]
17.

ABCB1 pharmacogenetics: progress, pitfalls, and promise.

Chinn LW, Kroetz DL.

Clin Pharmacol Ther. 2007 Feb;81(2):265-9. Review.

PMID:
17259950
[PubMed - indexed for MEDLINE]
18.

Predicting cancer drug response by proteomic profiling.

Ma Y, Ding Z, Qian Y, Shi X, Castranova V, Harner EJ, Guo L.

Clin Cancer Res. 2006 Aug 1;12(15):4583-9.

PMID:
16899605
[PubMed - indexed for MEDLINE]
Free Article
19.

Functional interactions between P-glycoprotein and CYP3A in drug metabolism.

Christians U, Schmitz V, Haschke M.

Expert Opin Drug Metab Toxicol. 2005 Dec;1(4):641-54. Review.

PMID:
16863430
[PubMed - indexed for MEDLINE]
20.

HapMap, pharmacogenomics, and the goal of personalized prescribing.

O'Shaughnessy KM.

Br J Clin Pharmacol. 2006 Jun;61(6):783-6. Review.

PMID:
16722846
[PubMed - indexed for MEDLINE]
Free PMC Article

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