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Results: 1 to 20 of 150

1.

Distribution study of orally administered lipoic acid in rat brain tissues.

Chng HT, New LS, Neo AH, Goh CW, Browne ER, Chan EC.

Brain Res. 2009 Jan 28;1251:80-6. doi: 10.1016/j.brainres.2008.11.025. Epub 2008 Nov 19.

PMID:
19046949
[PubMed - indexed for MEDLINE]
2.

Pharmacokinetics of different formulations of tioctic (alpha-lipoic) acid in healthy volunteers.

Amenta F, Traini E, Tomassoni D, Mignini F.

Clin Exp Hypertens. 2008 Nov;30(8):767-75. doi: 10.1080/10641960802563568. Erratum in: Clin Exp Hypertens. 2009 Feb;31(1):92.

PMID:
19021026
[PubMed - indexed for MEDLINE]
3.

Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.

Shay KP, Hagen TM.

Biogerontology. 2009 Aug;10(4):443-56. doi: 10.1007/s10522-008-9187-x. Epub 2008 Oct 18.

PMID:
18931933
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells.

Boivin B, Zhang S, Arbiser JL, Zhang ZY, Tonks NK.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9959-64. doi: 10.1073/pnas.0804336105. Epub 2008 Jul 16.

PMID:
18632564
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity.

Petersen Shay K, Moreau RF, Smith EJ, Hagen TM.

IUBMB Life. 2008 Jun;60(6):362-7. doi: 10.1002/iub.40. Review.

PMID:
18409172
[PubMed - indexed for MEDLINE]
6.

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity.

Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M.

Mol Cell Biol. 2008 Apr;28(8):2758-70. doi: 10.1128/MCB.01704-07. Epub 2008 Feb 11.

PMID:
18268004
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3.

Rachakonda G, Xiong Y, Sekhar KR, Stamer SL, Liebler DC, Freeman ML.

Chem Res Toxicol. 2008 Mar;21(3):705-10. doi: 10.1021/tx700302s. Epub 2008 Feb 6.

PMID:
18251510
[PubMed - indexed for MEDLINE]
8.

The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects.

Carlson DA, Smith AR, Fischer SJ, Young KL, Packer L.

Altern Med Rev. 2007 Dec;12(4):343-51.

PMID:
18069903
[PubMed - indexed for MEDLINE]
Free Article
9.

Comparative crossover, randomized, open-label bioequivalence study on the bioequivalence of two formulations of thioctic acid in healthy volunteers.

Mignini F, Streccioni V, Tomassoni D, Traini E, Amenta F.

Clin Exp Hypertens. 2007 Nov;29(8):575-86.

PMID:
18058482
[PubMed - indexed for MEDLINE]
10.

Postmitotic tissue selenium and manganese levels in alpha-lipoic acid-supplemented aged rats.

Cakatay U, Kayali R, Kiziler AR, Aydemir B.

Chem Biol Interact. 2008 Feb 15;171(3):306-11. Epub 2007 Oct 10.

PMID:
17996229
[PubMed - indexed for MEDLINE]
11.

Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.

Sena CM, Nunes E, Louro T, Proença T, Fernandes R, Boarder MR, Seiça RM.

Br J Pharmacol. 2008 Mar;153(5):894-906. Epub 2007 Oct 1.

PMID:
17906683
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes.

Shen QW, Zhu MJ, Tong J, Ren J, Du M.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1395-403. Epub 2007 Aug 8.

PMID:
17687000
[PubMed - indexed for MEDLINE]
Free Article
13.

Oxidative inhibition of protein phosphatase 2A activity: role of catalytic subunit disulfides.

Foley TD, Petro LA, Stredny CM, Coppa TM.

Neurochem Res. 2007 Nov;32(11):1957-64. Epub 2007 Jun 12.

PMID:
17562162
[PubMed - indexed for MEDLINE]
14.

Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers.

Takaishi N, Yoshida K, Satsu H, Shimizu M.

J Agric Food Chem. 2007 Jun 27;55(13):5253-9. Epub 2007 May 31.

PMID:
17536819
[PubMed - indexed for MEDLINE]
15.

Role of Akt substrate of 160 kDa in insulin-stimulated and contraction-stimulated glucose transport.

Cartee GD, Wojtaszewski JF.

Appl Physiol Nutr Metab. 2007 Jun;32(3):557-66. Review.

PMID:
17510697
[PubMed - indexed for MEDLINE]
16.

Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.

McMackin CJ, Widlansky ME, Hamburg NM, Huang AL, Weller S, Holbrook M, Gokce N, Hagen TM, Keaney JF Jr, Vita JA.

J Clin Hypertens (Greenwich). 2007 Apr;9(4):249-55.

PMID:
17396066
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.

Zhang WJ, Wei H, Hagen T, Frei B.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4077-82. Epub 2007 Feb 27.

PMID:
17360480
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Differential redox regulation within the PTP superfamily.

Ross SH, Lindsay Y, Safrany ST, Lorenzo O, Villa F, Toth R, Clague MJ, Downes CP, Leslie NR.

Cell Signal. 2007 Jul;19(7):1521-30. Epub 2007 Feb 6.

PMID:
17346927
[PubMed - indexed for MEDLINE]
19.

Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activity.

Kim HS, Kim HJ, Park KG, Kim YN, Kwon TK, Park JY, Lee KU, Kim JG, Lee IK.

Exp Mol Med. 2007 Feb 28;39(1):106-13.

PMID:
17334234
[PubMed - indexed for MEDLINE]
Free Article
20.

Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis.

Diesel B, Kulhanek-Heinze S, Höltje M, Brandt B, Höltje HD, Vollmar AM, Kiemer AK.

Biochemistry. 2007 Feb 27;46(8):2146-55. Epub 2007 Feb 3.

PMID:
17274632
[PubMed - indexed for MEDLINE]

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