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Items: 20


Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.

Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A.

Dev Cell. 2008 Jul;15(1):37-48. doi: 10.1016/j.devcel.2008.04.015.


The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin.

Jiang Y, Prunier C, Howe PH.

Oncogene. 2008 Mar 20;27(13):1865-75. Epub 2007 Oct 8.


A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida.

Rui Y, Xu Z, Xiong B, Cao Y, Lin S, Zhang M, Chan SC, Luo W, Han Y, Lu Z, Ye Z, Zhou HM, Han J, Meng A, Lin SC.

Dev Cell. 2007 Aug;13(2):268-82.


Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.

Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M, Niehrs C.

Science. 2007 Jun 15;316(5831):1619-22.


Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex.

Luo W, Peterson A, Garcia BA, Coombs G, Kofahl B, Heinrich R, Shabanowitz J, Hunt DF, Yost HJ, Virshup DM.

EMBO J. 2007 Mar 21;26(6):1511-21. Epub 2007 Feb 22.


Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling.

Yu A, Rual JF, Tamai K, Harada Y, Vidal M, He X, Kirchhausen T.

Dev Cell. 2007 Jan;12(1):129-41.


A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation.

Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, Okamura H, Woodgett J, He X.

Nature. 2005 Dec 8;438(7069):873-7.


Wnt signaling: physiology and pathology.

Prunier C, Hocevar BA, Howe PH.

Growth Factors. 2004 Sep;22(3):141-50. Review.


LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.

He X, Semenov M, Tamai K, Zeng X.

Development. 2004 Apr;131(8):1663-77. Review.


Crystal structures of the Dab homology domains of mouse disabled 1 and 2.

Yun M, Keshvara L, Park CG, Zhang YM, Dickerson JB, Zheng J, Rock CO, Curran T, Park HW.

J Biol Chem. 2003 Sep 19;278(38):36572-81. Epub 2003 Jun 24.


Wingless signaling: an axin to grind.

Jones WM, Bejsovec A.

Curr Biol. 2003 Jun 17;13(12):R479-81. Review.


Regulation of the Wnt signaling pathway by disabled-2 (Dab2).

Hocevar BA, Mou F, Rennolds JL, Morris SM, Cooper JA, Howe PH.

EMBO J. 2003 Jun 16;22(12):3084-94.


A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling.

Cliffe A, Hamada F, Bienz M.

Curr Biol. 2003 May 27;13(11):960-6.


Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton.

Morris SM, Arden SD, Roberts RC, Kendrick-Jones J, Cooper JA, Luzio JP, Buss F.

Traffic. 2002 May;3(5):331-41.


Wnt signaling controls the phosphorylation status of beta-catenin.

van Noort M, Meeldijk J, van der Zee R, Destree O, Clevers H.

J Biol Chem. 2002 May 17;277(20):17901-5. Epub 2002 Feb 7.


Disabled-2 mediates c-Fos suppression and the cell growth regulatory activity of retinoic acid in embryonic carcinoma cells.

Smith ER, Capo-chichi CD, He J, Smedberg JL, Yang DH, Prowse AH, Godwin AK, Hamilton TC, Xu XX.

J Biol Chem. 2001 Dec 14;276(50):47303-10. Epub 2001 Sep 27.


Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.

Morris SM, Cooper JA.

Traffic. 2001 Feb;2(2):111-23. Erratum in: Traffic 2002 Mar;3(3):236.


Linking colorectal cancer to Wnt signaling.

Bienz M, Clevers H.

Cell. 2000 Oct 13;103(2):311-20. Review. No abstract available.

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