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Items: 1 to 20 of 50

1.

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.

Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H, Planyavsky M, Bilban M, Colinge J, Bennett KL, Superti-Furga G.

Nat Immunol. 2009 Mar;10(3):266-72. doi: 10.1038/ni.1702. Epub 2009 Jan 21.

PMID:
19158679
2.

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.

Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES.

Nature. 2009 Mar 26;458(7237):509-13. doi: 10.1038/nature07710. Epub 2009 Jan 21.

3.

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.

Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA.

Nature. 2009 Mar 26;458(7237):514-8. doi: 10.1038/nature07725. Epub 2009 Jan 21.

4.

TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus.

Lee PY, Kumagai Y, Li Y, Takeuchi O, Yoshida H, Weinstein J, Kellner ES, Nacionales D, Barker T, Kelly-Scumpia K, van Rooijen N, Kumar H, Kawai T, Satoh M, Akira S, Reeves WH.

J Exp Med. 2008 Dec 22;205(13):2995-3006. doi: 10.1084/jem.20080462. Epub 2008 Dec 1.

5.

Tailoring T-cell receptor signals by proximal negative feedback mechanisms.

Acuto O, Di Bartolo V, Michel F.

Nat Rev Immunol. 2008 Sep;8(9):699-712. doi: 10.1038/nri2397. Review.

PMID:
18728635
6.

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling.

Ishikawa H, Barber GN.

Nature. 2008 Oct 2;455(7213):674-8. doi: 10.1038/nature07317. Epub 2008 Aug 24. Erratum in: Nature. 2008 Nov 13;456(7219):274.

7.

T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells.

Herlands RA, Christensen SR, Sweet RA, Hershberg U, Shlomchik MJ.

Immunity. 2008 Aug 15;29(2):249-60. doi: 10.1016/j.immuni.2008.06.009.

8.

Development of TLR inhibitors for the treatment of autoimmune diseases.

Barrat FJ, Coffman RL.

Immunol Rev. 2008 Jun;223:271-83. doi: 10.1111/j.1600-065X.2008.00630.x. Review.

PMID:
18613842
9.

Evidence for genes in addition to Tlr7 in the Yaa translocation linked with acceleration of systemic lupus erythematosus.

Santiago-Raber ML, Kikuchi S, Borel P, Uematsu S, Akira S, Kotzin BL, Izui S.

J Immunol. 2008 Jul 15;181(2):1556-62.

10.

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA.

Nature. 2008 Jun 19;453(7198):1122-6. doi: 10.1038/nature06939. Epub 2008 May 21.

11.

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.

Kim YM, Brinkmann MM, Paquet ME, Ploegh HL.

Nature. 2008 Mar 13;452(7184):234-8. doi: 10.1038/nature06726. Epub 2008 Feb 27.

PMID:
18305481
12.

The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation.

Haraldsson MK, Louis-Dit-Sully CA, Lawson BR, Sternik G, Santiago-Raber ML, Gascoigne NR, Theofilopoulos AN, Kono DH.

Immunity. 2008 Jan;28(1):40-51. doi: 10.1016/j.immuni.2007.11.023.

13.

Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation.

Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, Flavell RA, Bolland S.

Immunity. 2007 Nov;27(5):801-10. Epub 2007 Nov 8.

14.

T-cell sensitivity: a microRNA regulates the sensitivity of the T-cell receptor.

Laufer TM.

Immunol Cell Biol. 2007 Jul;85(5):346-7. Epub 2007 Jun 5. No abstract available.

15.

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity.

Baccala R, Hoebe K, Kono DH, Beutler B, Theofilopoulos AN.

Nat Med. 2007 May;13(5):543-51. Review.

PMID:
17479100
16.
17.

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling.

Gavin AL, Hoebe K, Duong B, Ota T, Martin C, Beutler B, Nemazee D.

Science. 2006 Dec 22;314(5807):1936-8.

18.

Virology. Sensing viral RNA amid your own.

Fujita T.

Science. 2006 Nov 10;314(5801):935-6. No abstract available.

PMID:
17095686
19.

5'-Triphosphate RNA is the ligand for RIG-I.

Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G.

Science. 2006 Nov 10;314(5801):994-7. Epub 2006 Oct 12.

20.

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates.

Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, Weber F, Reis e Sousa C.

Science. 2006 Nov 10;314(5801):997-1001. Epub 2006 Oct 12.

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