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Results: 1 to 20 of 117

References for PMC Articles for PubMed (Select 19557014)


Physiological functions of the HECT family of ubiquitin ligases.

Rotin D, Kumar S.

Nat Rev Mol Cell Biol. 2009 Jun;10(6):398-409. doi: 10.1038/nrm2690. Epub 2009 May 13. Review.


Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C.

Conkright JJ, Apsley KS, Martin EP, Ridsdale R, Rice WR, Na CL, Yang B, Weaver TE.

Am J Respir Cell Mol Biol. 2010 Feb;42(2):181-9. doi: 10.1165/rcmb.2009-0058OC. Epub 2009 May 7.


Anterograde transport of surfactant protein C proprotein to distal processing compartments requires PPDY-mediated association with Nedd4 ubiquitin ligases.

Kotorashvili A, Russo SJ, Mulugeta S, Guttentag S, Beers MF.

J Biol Chem. 2009 Jun 12;284(24):16667-78. doi: 10.1074/jbc.M109.002816. Epub 2009 Apr 14.


Abnormal development of the neuromuscular junction in Nedd4-deficient mice.

Liu Y, Oppenheim RW, Sugiura Y, Lin W.

Dev Biol. 2009 Jun 1;330(1):153-66. doi: 10.1016/j.ydbio.2009.03.023. Epub 2009 Apr 1.


Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation.

Xu P, Duong DM, Seyfried NT, Cheng D, Xie Y, Robert J, Rush J, Hochstrasser M, Finley D, Peng J.

Cell. 2009 Apr 3;137(1):133-45. doi: 10.1016/j.cell.2009.01.041.


SCAMP3 negatively regulates epidermal growth factor receptor degradation and promotes receptor recycling.

Aoh QL, Castle AM, Hubbard CH, Katsumata O, Castle JD.

Mol Biol Cell. 2009 Mar;20(6):1816-32. doi: 10.1091/mbc.E08-09-0894. Epub 2009 Jan 21.


Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.

Chan W, Tian R, Lee YF, Sit ST, Lim L, Manser E.

J Biol Chem. 2009 Mar 20;284(12):8185-94. doi: 10.1074/jbc.M806877200. Epub 2009 Jan 14.


The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4.

Plant PJ, Correa J, Goldenberg N, Bain J, Batt J.

Biochem J. 2009 Apr 1;419(1):57-63. doi: 10.1042/BJ20081866.


The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4.

Al Sorkhy M, Craig R, Market B, Ard R, Porter LA.

J Biol Chem. 2009 Jan 30;284(5):2617-27. doi: 10.1074/jbc.M804847200. Epub 2008 Dec 3.


Functional regulation of the epithelial Na+ channel by IkappaB kinase-beta occurs via phosphorylation of the ubiquitin ligase Nedd4-2.

Edinger RS, Lebowitz J, Li H, Alzamora R, Wang H, Johnson JP, Hallows KR.

J Biol Chem. 2009 Jan 2;284(1):150-7. doi: 10.1074/jbc.M807358200. Epub 2008 Nov 3.


Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface.

Lin CH, MacGurn JA, Chu T, Stefan CJ, Emr SD.

Cell. 2008 Nov 14;135(4):714-25. doi: 10.1016/j.cell.2008.09.025. Epub 2008 Oct 30.


Arrestin-like proteins mediate ubiquitination and endocytosis of the yeast metal transporter Smf1.

Nikko E, Sullivan JA, Pelham HR.

EMBO Rep. 2008 Dec;9(12):1216-21. doi: 10.1038/embor.2008.199. Epub 2008 Oct 24.


Nedd4 augments the adaptive immune response by promoting ubiquitin-mediated degradation of Cbl-b in activated T cells.

Yang B, Gay DL, MacLeod MK, Cao X, Hala T, Sweezer EM, Kappler J, Marrack P, Oliver PM.

Nat Immunol. 2008 Dec;9(12):1356-63. doi: 10.1038/ni.1670. Epub 2008 Oct 19.


Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins.

Putz U, Howitt J, Lackovic J, Foot N, Kumar S, Silke J, Tan SS.

J Biol Chem. 2008 Nov 21;283(47):32621-7. doi: 10.1074/jbc.M804120200. Epub 2008 Sep 25.


Nedd4 controls animal growth by regulating IGF-1 signaling.

Cao XR, Lill NL, Boase N, Shi PP, Croucher DR, Shan H, Qu J, Sweezer EM, Place T, Kirby PA, Daly RJ, Kumar S, Yang B.

Sci Signal. 2008 Sep 23;1(38):ra5. doi: 10.1126/scisignal.1160940.


Ubiquitin ligase E6-AP and its role in human disease.

Matentzoglu K, Scheffner M.

Biochem Soc Trans. 2008 Oct;36(Pt 5):797-801. doi: 10.1042/BST0360797.


Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

Foot NJ, Dalton HE, Shearwin-Whyatt LM, Dorstyn L, Tan SS, Yang B, Kumar S.

Blood. 2008 Nov 15;112(10):4268-75. doi: 10.1182/blood-2008-04-150953. Epub 2008 Sep 5.


gamma2-Adaptin, a ubiquitin-interacting adaptor, is a substrate to coupled ubiquitination by the ubiquitin ligase Nedd4 and functions in the endosomal pathway.

Rost M, Döring T, Prange R.

J Biol Chem. 2008 Nov 14;283(46):32119-30. doi: 10.1074/jbc.M802632200. Epub 2008 Sep 4.


An obligatory heterodimer of 14-3-3beta and 14-3-3epsilon is required for aldosterone regulation of the epithelial sodium channel.

Liang X, Butterworth MB, Peters KW, Walker WH, Frizzell RA.

J Biol Chem. 2008 Oct 10;283(41):27418-25. doi: 10.1074/jbc.M803687200. Epub 2008 Aug 7.


A quantitative atlas of mitotic phosphorylation.

Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31.

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