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Items: 1 to 20 of 51


A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer.

Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Chan AT, Schernhammer ES, Giovannucci EL, Fuchs CS.

J Natl Cancer Inst. 2008 Dec 3;100(23):1734-8. doi: 10.1093/jnci/djn359. Epub 2008 Nov 25.


Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.

Nosho K, Kawasaki T, Chan AT, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S.

Histopathology. 2008 Nov;53(5):588-98. doi: 10.1111/j.1365-2559.2008.03161.x.


CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.

Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, Giovannucci EL, Fuchs CS.

Gut. 2009 Jan;58(1):90-6. doi: 10.1136/gut.2008.155473. Epub 2008 Oct 2.


CpG island methylator phenotype associates with low-degree chromosomal abnormalities in colorectal cancer.

Cheng YW, Pincas H, Bacolod MD, Schemmann G, Giardina SF, Huang J, Barral S, Idrees K, Khan SA, Zeng Z, Rosenberg S, Notterman DA, Ott J, Paty P, Barany F.

Clin Cancer Res. 2008 Oct 1;14(19):6005-13. doi: 10.1158/1078-0432.CCR-08-0216.


Synergistic inhibition of ErbB signaling by combined treatment with seliciclib and ErbB-targeting agents.

Fleming IN, Hogben M, Frame S, McClue SJ, Green SR.

Clin Cancer Res. 2008 Jul 1;14(13):4326-35. doi: 10.1158/1078-0432.CCR-07-4633.


RHAMM, p21 combined phenotype identifies microsatellite instability-high colorectal cancers with a highly adverse prognosis.

Zlobec I, Baker K, Terracciano LM, Lugli A.

Clin Cancer Res. 2008 Jun 15;14(12):3798-806. doi: 10.1158/1078-0432.CCR-07-5103.


Local recurrence in mismatch repair-proficient colon cancer predicted by an infiltrative tumor border and lack of CD8+ tumor-infiltrating lymphocytes.

Zlobec I, Terracciano LM, Lugli A.

Clin Cancer Res. 2008 Jun 15;14(12):3792-7. doi: 10.1158/1078-0432.CCR-08-0048.


Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

French AJ, Sargent DJ, Burgart LJ, Foster NR, Kabat BF, Goldberg R, Shepherd L, Windschitl HE, Thibodeau SN.

Clin Cancer Res. 2008 Jun 1;14(11):3408-15. doi: 10.1158/1078-0432.CCR-07-1489.


Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.

Suehiro Y, Wong CW, Chirieac LR, Kondo Y, Shen L, Webb CR, Chan YW, Chan AS, Chan TL, Wu TT, Rashid A, Hamanaka Y, Hinoda Y, Shannon RL, Wang X, Morris J, Issa JP, Yuen ST, Leung SY, Hamilton SR.

Clin Cancer Res. 2008 May 1;14(9):2560-9. doi: 10.1158/1078-0432.CCR-07-1802.


LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.

Ogino S, Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS.

Int J Cancer. 2008 Jun 15;122(12):2767-73. doi: 10.1002/ijc.23470.


Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo.

Weichert W, Röske A, Niesporek S, Noske A, Buckendahl AC, Dietel M, Gekeler V, Boehm M, Beckers T, Denkert C.

Clin Cancer Res. 2008 Mar 15;14(6):1669-77. doi: 10.1158/1078-0432.CCR-07-0990.


Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy.

Morris M, Platell C, Iacopetta B.

Clin Cancer Res. 2008 Mar 1;14(5):1413-7. doi: 10.1158/1078-0432.CCR-07-1994.


Cortactin expression predicts poor survival in laryngeal carcinoma.

Gibcus JH, Mastik MF, Menkema L, de Bock GH, Kluin PM, Schuuring E, van der Wal JE.

Br J Cancer. 2008 Mar 11;98(5):950-5. doi: 10.1038/sj.bjc.6604246. Epub 2008 Feb 12.


Molecular classification and correlates in colorectal cancer.

Ogino S, Goel A.

J Mol Diagn. 2008 Jan;10(1):13-27. doi: 10.2353/jmoldx.2008.070082. Epub 2007 Dec 28. Review.


Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.

Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS.

J Mol Diagn. 2007 Jul;9(3):305-14.


Aspirin and the risk of colorectal cancer in relation to the expression of COX-2.

Chan AT, Ogino S, Fuchs CS.

N Engl J Med. 2007 May 24;356(21):2131-42.


Expression of peroxisome proliferator-activated receptor-gamma in colon cancer: correlation with histopathological parameters, cell cycle-related molecules, and patients' survival.

Theocharis S, Giaginis C, Parasi A, Margeli A, Kakisis J, Agapitos E, Kouraklis G.

Dig Dis Sci. 2007 Sep;52(9):2305-11. Epub 2007 Mar 28.


Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations.

Schmitz KJ, Wohlschlaeger J, Alakus H, Bohr J, Stauder MA, Worm K, Winde G, Schmid KW, Baba HA.

Virchows Arch. 2007 Feb;450(2):151-9.


Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP.

Ogino S, Kawasaki T, Kirkner GJ, Yamaji T, Loda M, Fuchs CS.

Mod Pathol. 2007 Jan;20(1):15-22. Epub 2006 Nov 3.

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