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Results: 18

1.

Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.

Goldgur Y, Paavilainen S, Nikolov D, Himanen JP.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Feb 1;65(Pt 2):71-4. doi: 10.1107/S1744309108043078. Epub 2009 Jan 31.

PMID:
19193989
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors.

Noberini R, Koolpe M, Peddibhotla S, Dahl R, Su Y, Cosford ND, Roth GP, Pasquale EB.

J Biol Chem. 2008 Oct 24;283(43):29461-72. doi: 10.1074/jbc.M804103200. Epub 2008 Aug 26.

PMID:
18728010
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor.

Qin H, Shi J, Noberini R, Pasquale EB, Song J.

J Biol Chem. 2008 Oct 24;283(43):29473-84. doi: 10.1074/jbc.M804114200. Epub 2008 Aug 14.

PMID:
18708347
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3.

Xu K, Rajashankar KR, Chan YP, Himanen JP, Broder CC, Nikolov DB.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9953-8. doi: 10.1073/pnas.0804797105. Epub 2008 Jul 16.

PMID:
18632560
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Kinetic analysis of the binding of monomeric and dimeric ephrins to Eph receptors: correlation to function in a growth cone collapse assay.

Pabbisetty KB, Yue X, Li C, Himanen JP, Zhou R, Nikolov DB, Hu L.

Protein Sci. 2007 Mar;16(3):355-61.

PMID:
17322526
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity.

Chrencik JE, Brooun A, Kraus ML, Recht MI, Kolatkar AR, Han GW, Seifert JM, Widmer H, Auer M, Kuhn P.

J Biol Chem. 2006 Sep 22;281(38):28185-92. Epub 2006 Jul 25.

PMID:
16867992
[PubMed - indexed for MEDLINE]
Free Article
7.

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.

Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B.

Cancer Res. 2006 Jul 15;66(14):7050-8.

PMID:
16849550
[PubMed - indexed for MEDLINE]
Free Article
8.

Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity.

Chrencik JE, Brooun A, Recht MI, Kraus ML, Koolpe M, Kolatkar AR, Bruce RH, Martiny-Baron G, Widmer H, Pasquale EB, Kuhn P.

Structure. 2006 Feb;14(2):321-30.

PMID:
16472751
[PubMed - indexed for MEDLINE]
Free Article
9.

Eph receptor signalling casts a wide net on cell behaviour.

Pasquale EB.

Nat Rev Mol Cell Biol. 2005 Jun;6(6):462-75. Review. Erratum in: Nat Rev Mol Cell Biol. 2005 Jul;6(7):589.

PMID:
15928710
[PubMed - indexed for MEDLINE]
10.

The CCP4 suite: programs for protein crystallography.

Collaborative Computational Project, Number 4.

Acta Crystallogr D Biol Crystallogr. 1994 Sep 1;50(Pt 5):760-3.

PMID:
15299374
[PubMed]
11.

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

Himanen JP, Chumley MJ, Lackmann M, Li C, Barton WA, Jeffrey PD, Vearing C, Geleick D, Feldheim DA, Boyd AW, Henkemeyer M, Nikolov DB.

Nat Neurosci. 2004 May;7(5):501-9. Epub 2004 Apr 25.

PMID:
15107857
[PubMed - indexed for MEDLINE]
12.

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis.

Miao H, Nickel CH, Cantley LG, Bruggeman LA, Bennardo LN, Wang B.

J Cell Biol. 2003 Sep 29;162(7):1281-92.

PMID:
14517207
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Eph signaling: a structural view.

Himanen JP, Nikolov DB.

Trends Neurosci. 2003 Jan;26(1):46-51. Review.

PMID:
12495863
[PubMed - indexed for MEDLINE]
14.

An ephrin mimetic peptide that selectively targets the EphA2 receptor.

Koolpe M, Dail M, Pasquale EB.

J Biol Chem. 2002 Dec 6;277(49):46974-9. Epub 2002 Sep 25.

PMID:
12351647
[PubMed - indexed for MEDLINE]
Free Article
15.

Crystal structure of an Eph receptor-ephrin complex.

Himanen JP, Rajashankar KR, Lackmann M, Cowan CA, Henkemeyer M, Nikolov DB.

Nature. 2001 Dec 20-27;414(6866):933-8.

PMID:
11780069
[PubMed - indexed for MEDLINE]
16.

Crystallography & NMR system: A new software suite for macromolecular structure determination.

BrĂ¼nger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS, Read RJ, Rice LM, Simonson T, Warren GL.

Acta Crystallogr D Biol Crystallogr. 1998 Sep 1;54(Pt 5):905-21.

PMID:
9757107
[PubMed - indexed for MEDLINE]
17.

Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization.

Lackmann M, Oates AC, Dottori M, Smith FM, Do C, Power M, Kravets L, Boyd AW.

J Biol Chem. 1998 Aug 7;273(32):20228-37.

PMID:
9685371
[PubMed - indexed for MEDLINE]
Free Article
18.

Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.

Davis S, Gale NW, Aldrich TH, Maisonpierre PC, Lhotak V, Pawson T, Goldfarb M, Yancopoulos GD.

Science. 1994 Nov 4;266(5186):816-9.

PMID:
7973638
[PubMed - indexed for MEDLINE]

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