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Items: 1 to 20 of 57

1.

Protection from high fat diet-induced increase in ceramide in mice lacking plasminogen activator inhibitor 1.

Shah C, Yang G, Lee I, Bielawski J, Hannun YA, Samad F.

J Biol Chem. 2008 May 16;283(20):13538-48. doi: 10.1074/jbc.M709950200. Epub 2008 Mar 22.

2.

SOCS proteins causing trouble in insulin action.

Lebrun P, Van Obberghen E.

Acta Physiol (Oxf). 2008 Jan;192(1):29-36. doi: 10.1111/j.1748-1716.2007.01782.x. Review.

PMID:
18171427
3.

Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity.

Cernkovich ER, Deng J, Bond MC, Combs TP, Harp JB.

Endocrinology. 2008 Apr;149(4):1581-90. Epub 2007 Dec 20.

4.

Lipid raft proteomics: more than just detergent-resistant membranes.

Foster LJ, Chan QW.

Subcell Biochem. 2007;43:35-47. Review.

PMID:
17953390
5.

Non-alcoholic fatty liver disease in the metabolic syndrome.

Palasciano G, Moschetta A, Palmieri VO, Grattagliano I, Iacobellis G, Portincasa P.

Curr Pharm Des. 2007;13(21):2193-8. Review.

PMID:
17627552
6.

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

Kolak M, Westerbacka J, Velagapudi VR, Wågsäter D, Yetukuri L, Makkonen J, Rissanen A, Häkkinen AM, Lindell M, Bergholm R, Hamsten A, Eriksson P, Fisher RM, Oresic M, Yki-Järvinen H.

Diabetes. 2007 Aug;56(8):1960-8. Epub 2007 Jul 9.

7.

Liver-specific knockdown of JNK1 up-regulates proliferator-activated receptor gamma coactivator 1 beta and increases plasma triglyceride despite reduced glucose and insulin levels in diet-induced obese mice.

Yang R, Wilcox DM, Haasch DL, Jung PM, Nguyen PT, Voorbach MJ, Doktor S, Brodjian S, Bush EN, Lin E, Jacobson PB, Collins CA, Landschulz KT, Trevillyan JM, Rondinone CM, Surowy TK.

J Biol Chem. 2007 Aug 3;282(31):22765-74. Epub 2007 Jun 5.

8.

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance.

Holland WL, Brozinick JT, Wang LP, Hawkins ED, Sargent KM, Liu Y, Narra K, Hoehn KL, Knotts TA, Siesky A, Nelson DH, Karathanasis SK, Fontenot GK, Birnbaum MJ, Summers SA.

Cell Metab. 2007 Mar;5(3):167-79.

9.

Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression.

Kanatani Y, Usui I, Ishizuka K, Bukhari A, Fujisaka S, Urakaze M, Haruta T, Kishimoto T, Naka T, Kobayashi M.

Diabetes. 2007 Mar;56(3):795-803.

10.

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.

Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N.

J Clin Invest. 2007 Feb;117(2):387-96.

11.

Obesity induces a phenotypic switch in adipose tissue macrophage polarization.

Lumeng CN, Bodzin JL, Saltiel AR.

J Clin Invest. 2007 Jan;117(1):175-84.

12.

Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity.

Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR.

Diabetes. 2007 Jan;56(1):16-23.

13.

Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy.

Zheng W, Kollmeyer J, Symolon H, Momin A, Munter E, Wang E, Kelly S, Allegood JC, Liu Y, Peng Q, Ramaraju H, Sullards MC, Cabot M, Merrill AH Jr.

Biochim Biophys Acta. 2006 Dec;1758(12):1864-84. Epub 2006 Aug 22. Review.

14.

Attenuation of leptin and insulin signaling by SOCS proteins.

Howard JK, Flier JS.

Trends Endocrinol Metab. 2006 Nov;17(9):365-71. Epub 2006 Sep 28. Review.

PMID:
17010638
15.
16.
17.

The suppressor of cytokine signaling 3 inhibits leptin activation of AMP-kinase in cultured skeletal muscle of obese humans.

Steinberg GR, McAinch AJ, Chen MB, O'Brien PE, Dixon JB, Cameron-Smith D, Kemp BE.

J Clin Endocrinol Metab. 2006 Sep;91(9):3592-7. Epub 2006 Jul 5.

PMID:
16822822
18.

Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.

Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T.

J Biol Chem. 2006 Sep 8;281(36):26602-14. Epub 2006 Jun 29.

19.

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis.

Pewzner-Jung Y, Ben-Dor S, Futerman AH.

J Biol Chem. 2006 Sep 1;281(35):25001-5. Epub 2006 Jun 22. Review. No abstract available.

20.

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity.

Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M.

J Clin Invest. 2006 Jun;116(6):1494-505. Epub 2006 May 11.

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