Format
Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 43

1.

The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis.

Mickler M, Hessling M, Ratzke C, Buchner J, Hugel T.

Nat Struct Mol Biol. 2009 Mar;16(3):281-6. doi: 10.1038/nsmb.1557. Epub 2009 Feb 22.

PMID:
19234469
2.

Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90.

Hessling M, Richter K, Buchner J.

Nat Struct Mol Biol. 2009 Mar;16(3):287-93. doi: 10.1038/nsmb.1565. Epub 2009 Feb 22.

PMID:
19234467
3.

Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine.

Graf C, Stankiewicz M, Kramer G, Mayer MP.

EMBO J. 2009 Mar 4;28(5):602-13. doi: 10.1038/emboj.2008.306. Epub 2009 Jan 22.

4.

Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma.

Solit DB, Osman I, Polsky D, Panageas KS, Daud A, Goydos JS, Teitcher J, Wolchok JD, Germino FJ, Krown SE, Coit D, Rosen N, Chapman PB.

Clin Cancer Res. 2008 Dec 15;14(24):8302-7. doi: 10.1158/1078-0432.CCR-08-1002.

5.

Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle.

Southworth DR, Agard DA.

Mol Cell. 2008 Dec 5;32(5):631-40. doi: 10.1016/j.molcel.2008.10.024.

6.

Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90.

Cunningham CN, Krukenberg KA, Agard DA.

J Biol Chem. 2008 Jul 25;283(30):21170-8. doi: 10.1074/jbc.M800046200. Epub 2008 May 20.

7.

Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.

Krukenberg KA, Förster F, Rice LM, Sali A, Agard DA.

Structure. 2008 May;16(5):755-65. doi: 10.1016/j.str.2008.01.021.

8.
9.

Illuminating the mechanistic roles of enzyme conformational dynamics.

Hanson JA, Duderstadt K, Watkins LP, Bhattacharyya S, Brokaw J, Chu JW, Yang H.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18055-60. Epub 2007 Nov 7.

10.

Structures of GRP94-nucleotide complexes reveal mechanistic differences between the hsp90 chaperones.

Dollins DE, Warren JJ, Immormino RM, Gewirth DT.

Mol Cell. 2007 Oct 12;28(1):41-56.

11.

The ATPase cycle of the endoplasmic chaperone Grp94.

Frey S, Leskovar A, Reinstein J, Buchner J.

J Biol Chem. 2007 Dec 7;282(49):35612-20. Epub 2007 Oct 9.

12.

Heat shock protein 90: the cancer chaperone.

Neckers L.

J Biosci. 2007 Apr;32(3):517-30. Review.

13.

Molecular chaperones and protein kinase quality control.

Caplan AJ, Mandal AK, Theodoraki MA.

Trends Cell Biol. 2007 Feb;17(2):87-92. Epub 2006 Dec 20. Review.

PMID:
17184992
14.

Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements.

Shiau AK, Harris SF, Southworth DR, Agard DA.

Cell. 2006 Oct 20;127(2):329-40.

15.

Chaperoning steroid hormone action.

Picard D.

Trends Endocrinol Metab. 2006 Aug;17(6):229-35. Epub 2006 Jun 27. Review.

PMID:
16806964
16.

Structure and mechanism of the Hsp90 molecular chaperone machinery.

Pearl LH, Prodromou C.

Annu Rev Biochem. 2006;75:271-94. Review.

PMID:
16756493
17.

Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex.

Ali MM, Roe SM, Vaughan CK, Meyer P, Panaretou B, Piper PW, Prodromou C, Pearl LH.

Nature. 2006 Apr 20;440(7087):1013-7.

PMID:
16625188
18.

Effect of hsp70 chaperone on the folding and misfolding of polypeptides modeling an elongating protein chain.

Kurt N, Rajagopalan S, Cavagnero S.

J Mol Biol. 2006 Jan 27;355(4):809-20. Epub 2005 Nov 8.

19.

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.

Zhao R, Davey M, Hsu YC, Kaplanek P, Tong A, Parsons AB, Krogan N, Cagney G, Mai D, Greenblatt J, Boone C, Emili A, Houry WA.

Cell. 2005 Mar 11;120(5):715-27.

20.

Perturbation of the conformational equilibria in Ras by selective mutations as studied by 31P NMR spectroscopy.

Spoerner M, Wittinghofer A, Kalbitzer HR.

FEBS Lett. 2004 Dec 17;578(3):305-10.

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk