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References for PMC Articles for PubMed (Select 19420133)


Human flavin-containing monooxygenase 2.1 catalyzes oxygenation of the antitubercular drugs thiacetazone and ethionamide.

Francois AA, Nishida CR, de Montellano PR, Phillips IR, Shephard EA.

Drug Metab Dispos. 2009 Jan;37(1):178-86. doi: 10.1124/dmd.108.024158. Epub 2008 Oct 23.


Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes.

Henderson MC, Siddens LK, Morré JT, Krueger SK, Williams DE.

Toxicol Appl Pharmacol. 2008 Dec 15;233(3):420-7. doi: 10.1016/j.taap.2008.09.017. Epub 2008 Oct 1.


The potentially deleterious functional variant flavin-containing monooxygenase 2*1 is at high frequency throughout sub-Saharan Africa.

Veeramah KR, Thomas MG, Weale ME, Zeitlyn D, Tarekegn A, Bekele E, Mendell NR, Shephard EA, Bradman N, Phillips IR.

Pharmacogenet Genomics. 2008 Oct;18(10):877-86. doi: 10.1097/FPC.0b013e3283097311.


Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase.

Alfieri A, Malito E, Orru R, Fraaije MW, Mattevi A.

Proc Natl Acad Sci U S A. 2008 May 6;105(18):6572-7. doi: 10.1073/pnas.0800859105. Epub 2008 Apr 28.


Flavin-containing monooxygenases: mutations, disease and drug response.

Phillips IR, Shephard EA.

Trends Pharmacol Sci. 2008 Jun;29(6):294-301. doi: 10.1016/ Epub 2008 Apr 16. Review.


Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.

Siddens LK, Henderson MC, Vandyke JE, Williams DE, Krueger SK.

Biochem Pharmacol. 2008 Jan 15;75(2):570-9. Epub 2007 Sep 8.


Clustal W and Clustal X version 2.0.

Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, Thompson JD, Gibson TJ, Higgins DG.

Bioinformatics. 2007 Nov 1;23(21):2947-8. Epub 2007 Sep 10.


Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.

Yeung CK, Adman ET, Rettie AE.

Arch Biochem Biophys. 2007 Aug 15;464(2):251-9. Epub 2007 May 2.


PTC124 targets genetic disorders caused by nonsense mutations.

Welch EM, Barton ER, Zhuo J, Tomizawa Y, Friesen WJ, Trifillis P, Paushkin S, Patel M, Trotta CR, Hwang S, Wilde RG, Karp G, Takasugi J, Chen G, Jones S, Ren H, Moon YC, Corson D, Turpoff AA, Campbell JA, Conn MM, Khan A, Almstead NG, Hedrick J, Mollin A, Risher N, Weetall M, Yeh S, Branstrom AA, Colacino JM, Babiak J, Ju WD, Hirawat S, Northcutt VJ, Miller LL, Spatrick P, He F, Kawana M, Feng H, Jacobson A, Peltz SW, Sweeney HL.

Nature. 2007 May 3;447(7140):87-91. Epub 2007 Apr 22.


Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.

Koukouritaki SB, Poch MT, Henderson MC, Siddens LK, Krueger SK, VanDyke JE, Williams DE, Pajewski NM, Wang T, Hines RN.

J Pharmacol Exp Ther. 2007 Jan;320(1):266-73. Epub 2006 Oct 18.


Mechanism of action of a flavin-containing monooxygenase.

Eswaramoorthy S, Bonanno JB, Burley SK, Swaminathan S.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9832-7. Epub 2006 Jun 15. Erratum in: Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14543.


Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts.

van Berkel WJ, Kamerbeek NM, Fraaije MW.

J Biotechnol. 2006 Aug 5;124(4):670-89. Epub 2006 May 19. Review.


Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase.

van den Heuvel RH, Tahallah N, Kamerbeek NM, Fraaije MW, van Berkel WJ, Janssen DB, Heck AJ.

J Biol Chem. 2005 Sep 16;280(37):32115-21. Epub 2005 Jul 27.


Haplotype and functional analysis of four flavin-containing monooxygenase isoform 2 (FMO2) polymorphisms in Hispanics.

Krueger SK, Siddens LK, Henderson MC, Andreasen EA, Tanguay RL, Pereira CB, Cabacungan ET, Hines RN, Ardlie KG, Williams DE.

Pharmacogenet Genomics. 2005 Apr;15(4):245-56.


Differences in FMO2*1 allelic frequency between Hispanics of Puerto Rican and Mexican descent.

Krueger SK, Siddens LK, Martin SR, Yu Z, Pereira CB, Cabacungan ET, Hines RN, Ardlie KG, Raucy JL, Williams DE.

Drug Metab Dispos. 2004 Dec;32(12):1337-40. Epub 2004 Sep 8.


Crystal structure of a Baeyer-Villiger monooxygenase.

Malito E, Alfieri A, Fraaije MW, Mattevi A.

Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13157-62. Epub 2004 Aug 24.


S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2.

Henderson MC, Krueger SK, Siddens LK, Stevens JF, Williams DE.

Biochem Pharmacol. 2004 Sep 1;68(5):959-67.


Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.

Henderson MC, Krueger SK, Stevens JF, Williams DE.

Chem Res Toxicol. 2004 May;17(5):633-40.

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