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Items: 1 to 20 of 23

1.

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR.

Cell. 2008 Feb 8;132(3):363-74. doi: 10.1016/j.cell.2007.12.032.

2.

An elaborate pathway required for Ras-mediated epigenetic silencing.

Gazin C, Wajapeyee N, Gobeil S, Virbasius CM, Green MR.

Nature. 2007 Oct 25;449(7165):1073-7.

3.

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.

5.

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

Mallette FA, Gaumont-Leclerc MF, Ferbeyre G.

Genes Dev. 2007 Jan 1;21(1):43-8.

6.

A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation.

Okabe H, Lee SH, Phuchareon J, Albertson DG, McCormick F, Tetsu O.

PLoS One. 2006 Dec 27;1:e128.

7.

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.

Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F.

Nature. 2006 Nov 30;444(7119):638-42.

PMID:
17136094
8.

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.

Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG.

Nature. 2006 Nov 30;444(7119):633-7.

PMID:
17136093
9.

Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex.

Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA.

Mol Cell. 2006 Nov 3;24(3):355-66.

10.

The ATM-mediated DNA-damage response: taking shape.

Shiloh Y.

Trends Biochem Sci. 2006 Jul;31(7):402-10. Epub 2006 Jun 13.

PMID:
16774833
11.

F-box proteins: the key to protein degradation.

Ho MS, Tsai PI, Chien CT.

J Biomed Sci. 2006 Mar;13(2):181-91. Review.

PMID:
16463014
12.

FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex.

Kumar R, Neilsen PM, Crawford J, McKirdy R, Lee J, Powell JA, Saif Z, Martin JM, Lombaerts M, Cornelisse CJ, Cleton-Jansen AM, Callen DF.

Cancer Res. 2005 Dec 15;65(24):11304-13.

13.

Loss of heterozygosity in chromosomal region 16q24.3 associated with progression of prostate cancer.

Härkönen P, Kyllönen AP, Nordling S, Vihko P.

Prostate. 2005 Feb 15;62(3):267-74.

PMID:
15389780
14.

Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression.

Newman RM, Mobascher A, Mangold U, Koike C, Diah S, Schmidt M, Finley D, Zetter BR.

J Biol Chem. 2004 Oct 1;279(40):41504-11. Epub 2004 Jul 23.

16.

Deletion mapping of chromosome 16q24 in hepatocellular carcinoma in Taiwan and mutational analysis of the 17-beta-HSD gene localized to the region.

Lin YW, Lee IN, Chen CH, Huang GT, Lee HS, Lee PH, Lu FJ, Sheu JC.

Int J Cancer. 2001 Jul 1;93(1):74-9.

17.

Loss of heterozygosity at chromosomes 3, 6, 8, 11, 16, and 17 in ovarian cancer: correlation to clinicopathological variables.

Launonen V, Mannermaa A, Stenbäck F, Kosma VM, Puistola U, Huusko P, Anttila M, Bloigu R, Saarikoski S, Kauppila A, Winqvist R.

Cancer Genet Cytogenet. 2000 Oct 1;122(1):49-54.

PMID:
11104033
18.

The DNA damage response: putting checkpoints in perspective.

Zhou BB, Elledge SJ.

Nature. 2000 Nov 23;408(6811):433-9. Review.

PMID:
11100718
20.

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization.

Diehl JA, Cheng M, Roussel MF, Sherr CJ.

Genes Dev. 1998 Nov 15;12(22):3499-511.

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