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Items: 1 to 20 of 32


Comparison of a commercial real-time PCR assay for tcdB detection to a cell culture cytotoxicity assay and toxigenic culture for direct detection of toxin-producing Clostridium difficile in clinical samples.

Stamper PD, Alcabasa R, Aird D, Babiker W, Wehrlin J, Ikpeama I, Carroll KC.

J Clin Microbiol. 2009 Feb;47(2):373-8. doi: 10.1128/JCM.01613-08. Epub 2008 Dec 10.


Comparison of real-time PCR for detection of the tcdC gene with four toxin immunoassays and culture in diagnosis of Clostridium difficile infection.

Sloan LM, Duresko BJ, Gustafson DR, Rosenblatt JE.

J Clin Microbiol. 2008 Jun;46(6):1996-2001. doi: 10.1128/JCM.00032-08. Epub 2008 Apr 23.


Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing.

Killgore G, Thompson A, Johnson S, Brazier J, Kuijper E, Pepin J, Frost EH, Savelkoul P, Nicholson B, van den Berg RJ, Kato H, Sambol SP, Zukowski W, Woods C, Limbago B, Gerding DN, McDonald LC.

J Clin Microbiol. 2008 Feb;46(2):431-7. Epub 2007 Nov 26.


A possible role for Clostridium difficile in the etiology of calf enteritis.

Hammitt MC, Bueschel DM, Keel MK, Glock RD, Cuneo P, DeYoung DW, Reggiardo C, Trinh HT, Songer JG.

Vet Microbiol. 2008 Mar 18;127(3-4):343-52. Epub 2007 Sep 18.


Detection of toxigenic Clostridium difficile in stool samples by real-time polymerase chain reaction for the diagnosis of C. difficile-associated diarrhea.

Peterson LR, Manson RU, Paule SM, Hacek DM, Robicsek A, Thomson RB Jr, Kaul KL.

Clin Infect Dis. 2007 Nov 1;45(9):1152-60. Epub 2007 Sep 25.


Variant forms of the binary toxin CDT locus and tcdC gene in Clostridium difficile strains.

Stare BG, Delmée M, Rupnik M.

J Med Microbiol. 2007 Mar;56(Pt 3):329-35.


Emergence of Clostridium difficile toxinotype III, PCR-ribotype 027-associated disease, France, 2006.

Coignard B, Barbut F, Blanckaert K, Thiolet JM, Poujol I, Carbonne A, Petit JC, Desenclos JC.

Euro Surveill. 2006 Sep 14;11(9):E060914.1. No abstract available.


tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile.

Curry SR, Marsh JW, Muto CA, O'Leary MM, Pasculle AW, Harrison LH.

J Clin Microbiol. 2007 Jan;45(1):215-21. Epub 2006 Oct 11. Erratum in: J Clin Microbiol. 2007 Jun;45(6):2103.


Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains.

Stabler RA, Gerding DN, Songer JG, Drudy D, Brazier JS, Trinh HT, Witney AA, Hinds J, Wren BW.

J Bacteriol. 2006 Oct;188(20):7297-305.


Emergence of Clostridium difficile-associated disease in North America and Europe.

Kuijper EJ, Coignard B, Tüll P; ESCMID Study Group for Clostridium difficile; EU Member States; European Centre for Disease Prevention and Control.

Clin Microbiol Infect. 2006 Oct;12 Suppl 6:2-18. Review.


Binary toxin producing Clostridium difficile strains.

Rupnik M, Grabnar M, Geric B.

Anaerobe. 2003 Dec;9(6):289-94.


Molecular analysis of Clostridium difficile PCR ribotype 027 isolates from Eastern and Western Canada.

MacCannell DR, Louie TJ, Gregson DB, Laverdiere M, Labbe AC, Laing F, Henwick S.

J Clin Microbiol. 2006 Jun;44(6):2147-52.


Clostridium difficile ribotype 027, toxinotype III, the Netherlands.

Kuijper EJ, van den Berg RJ, Debast S, Visser CE, Veenendaal D, Troelstra A, van der Kooi T, van den Hof S, Notermans DW.

Emerg Infect Dis. 2006 May;12(5):827-30.


Rapid diagnosis of toxinogenic Clostridium difficile in faecal samples with internally controlled real-time PCR.

van den Berg RJ, Kuijper EJ, van Coppenraet LE, Claas EC.

Clin Microbiol Infect. 2006 Feb;12(2):184-6.


An epidemic, toxin gene-variant strain of Clostridium difficile.

McDonald LC, Killgore GE, Thompson A, Owens RC Jr, Kazakova SV, Sambol SP, Johnson S, Gerding DN.

N Engl J Med. 2005 Dec 8;353(23):2433-41. Epub 2005 Dec 1.


A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality.

Loo VG, Poirier L, Miller MA, Oughton M, Libman MD, Michaud S, Bourgault AM, Nguyen T, Frenette C, Kelly M, Vibien A, Brassard P, Fenn S, Dewar K, Hudson TJ, Horn R, René P, Monczak Y, Dascal A.

N Engl J Med. 2005 Dec 8;353(23):2442-9. Epub 2005 Dec 1. Erratum in: N Engl J Med. 2006 May 18;354(20):2200.


Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe.

Warny M, Pepin J, Fang A, Killgore G, Thompson A, Brazier J, Frost E, McDonald LC.

Lancet. 2005 Sep 24-30;366(9491):1079-84.


Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actin-specific ADP-ribosyltransferase)-producing strains.

Barbut F, Decré D, Lalande V, Burghoffer B, Noussair L, Gigandon A, Espinasse F, Raskine L, Robert J, Mangeol A, Branger C, Petit JC.

J Med Microbiol. 2005 Feb;54(Pt 2):181-5.


Coexistence of multiple PCR-ribotype strains of Clostridium difficile in faecal samples limits epidemiological studies.

van den Berg RJ, Ameen HA, Furusawa T, Claas EC, van der Vorm ER, Kuijper EJ.

J Med Microbiol. 2005 Feb;54(Pt 2):173-9.

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