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Items: 1 to 20 of 33


Role of ULK-FIP200 complex in mammalian autophagy: FIP200, a counterpart of yeast Atg17?

Hara T, Mizushima N.

Autophagy. 2009 Jan;5(1):85-7. Epub 2009 Jan 13.


Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.

Chan EY, Longatti A, McKnight NC, Tooze SA.

Mol Cell Biol. 2009 Jan;29(1):157-71. doi: 10.1128/MCB.01082-08. Epub 2008 Oct 20.


Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation.

Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, Selak MA, Ney PA, Thompson CB.

Blood. 2008 Aug 15;112(4):1493-502. doi: 10.1182/blood-2008-02-137398. Epub 2008 Jun 6.


FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.

Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N.

J Cell Biol. 2008 May 5;181(3):497-510. doi: 10.1083/jcb.200712064. Epub 2008 Apr 28.


FIP200, a key signaling node to coordinately regulate various cellular processes.

Gan B, Guan JL.

Cell Signal. 2008 May;20(5):787-94. Epub 2007 Nov 1. Review.


Autophagy: process and function.

Mizushima N.

Genes Dev. 2007 Nov 15;21(22):2861-73. Review.


siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.

Chan EY, Kir S, Tooze SA.

J Biol Chem. 2007 Aug 31;282(35):25464-74. Epub 2007 Jun 26.


Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae.

Suzuki K, Ohsumi Y.

FEBS Lett. 2007 May 22;581(11):2156-61. Epub 2007 Mar 12.


ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes.

Meijer WH, van der Klei IJ, Veenhuis M, Kiel JA.

Autophagy. 2007 Mar-Apr;3(2):106-16. Epub 2007 Apr 13.


Stimulation of ATG12-ATG5 conjugation by ribonucleic acid.

Shao Y, Gao Z, Feldman T, Jiang X.

Autophagy. 2007 Jan-Feb;3(1):10-6. Epub 2007 Jan 27.


Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes.

Young AR, Chan EY, Hu XW, Köchl R, Crawshaw SG, High S, Hailey DW, Lippincott-Schwartz J, Tooze SA.

J Cell Sci. 2006 Sep 15;119(Pt 18):3888-900. Epub 2006 Aug 29.


Human IRGM induces autophagy to eliminate intracellular mycobacteria.

Singh SB, Davis AS, Taylor GA, Deretic V.

Science. 2006 Sep 8;313(5792):1438-41. Epub 2006 Aug 3.


Loss of autophagy in the central nervous system causes neurodegeneration in mice.

Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, Tanaka K.

Nature. 2006 Jun 15;441(7095):880-4. Epub 2006 Apr 19.


Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.

Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N.

Nature. 2006 Jun 15;441(7095):885-9. Epub 2006 Apr 19.


Autophagy: molecular machinery for self-eating.

Yorimitsu T, Klionsky DJ.

Cell Death Differ. 2005 Nov;12 Suppl 2:1542-52. Review.


Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.

Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B.

Cell. 2005 Sep 23;122(6):927-39.


An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase.

Budovskaya YV, Stephan JS, Deminoff SJ, Herman PK.

Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13933-8. Epub 2005 Sep 19.


Atg17 regulates the magnitude of the autophagic response.

Cheong H, Yorimitsu T, Reggiori F, Legakis JE, Wang CW, Klionsky DJ.

Mol Biol Cell. 2005 Jul;16(7):3438-53. Epub 2005 May 18.


Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy.

Kabeya Y, Kamada Y, Baba M, Takikawa H, Sasaki M, Ohsumi Y.

Mol Biol Cell. 2005 May;16(5):2544-53. Epub 2005 Mar 2.


The molecular machinery of autophagy: unanswered questions.

Klionsky DJ.

J Cell Sci. 2005 Jan 1;118(Pt 1):7-18.

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