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Results: 1 to 20 of 39

1.

Role of platelet-derived growth factors in physiology and medicine.

Andrae J, Gallini R, Betsholtz C.

Genes Dev. 2008 May 15;22(10):1276-312. doi: 10.1101/gad.1653708. Review.

PMID:
18483217
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis.

Hardie WD, Davidson C, Ikegami M, Leikauf GD, Le Cras TD, Prestridge A, Whitsett JA, Korfhagen TR.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1217-25. doi: 10.1152/ajplung.00020.2008. Epub 2008 Apr 18.

PMID:
18424623
[PubMed - indexed for MEDLINE]
Free Article
3.

The potential role of mTOR inhibitors in non-small cell lung cancer.

Gridelli C, Maione P, Rossi A.

Oncologist. 2008 Feb;13(2):139-47. doi: 10.1634/theoncologist.2007-0171. Review.

PMID:
18305058
[PubMed - indexed for MEDLINE]
Free Article
4.

Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.

Bissler JJ, McCormack FX, Young LR, Elwing JM, Chuck G, Leonard JM, Schmithorst VJ, Laor T, Brody AS, Bean J, Salisbury S, Franz DN.

N Engl J Med. 2008 Jan 10;358(2):140-51. doi: 10.1056/NEJMoa063564.

PMID:
18184959
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat.

Krämer S, Wang-Rosenke Y, Scholl V, Binder E, Loof T, Khadzhynov D, Kawachi H, Shimizu F, Diekmann F, Budde K, Neumayer HH, Peters H.

Am J Physiol Renal Physiol. 2008 Feb;294(2):F440-9. Epub 2007 Dec 19.

PMID:
18094032
[PubMed - indexed for MEDLINE]
Free Article
6.

TGF-beta signaling: a tale of two responses.

Rahimi RA, Leof EB.

J Cell Biochem. 2007 Oct 15;102(3):593-608. Review.

PMID:
17729308
[PubMed - indexed for MEDLINE]
7.

Rapamycin: something old, something new, sometimes borrowed and now renewed.

Hartford CM, Ratain MJ.

Clin Pharmacol Ther. 2007 Oct;82(4):381-8. Epub 2007 Aug 29. Review.

PMID:
17728765
[PubMed - indexed for MEDLINE]
8.

Molecular mechanisms of hepatic fibrogenesis.

Parsons CJ, Takashima M, Rippe RA.

J Gastroenterol Hepatol. 2007 Jun;22 Suppl 1:S79-84. Review. Erratum in: J Gastroenterol Hepatol. 2008 Mar;23(3):501-2.

PMID:
17567474
[PubMed - indexed for MEDLINE]
9.
10.

Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.

Hardie WD, Korfhagen TR, Sartor MA, Prestridge A, Medvedovic M, Le Cras TD, Ikegami M, Wesselkamper SC, Davidson C, Dietsch M, Nichols W, Whitsett JA, Leikauf GD.

Am J Respir Cell Mol Biol. 2007 Sep;37(3):309-21. Epub 2007 May 11.

PMID:
17496152
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis.

Kang HR, Lee CG, Homer RJ, Elias JA.

J Exp Med. 2007 May 14;204(5):1083-93. Epub 2007 May 7.

PMID:
17485510
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis.

Neef M, Ledermann M, Saegesser H, Schneider V, Reichen J.

J Hepatol. 2006 Dec;45(6):786-96. Epub 2006 Sep 22. Erratum in: J Hepatol. 2007 Aug;47(2):310.

PMID:
17050028
[PubMed - indexed for MEDLINE]
13.

Current perspectives on the treatment of idiopathic pulmonary fibrosis.

Walter N, Collard HR, King TE Jr.

Proc Am Thorac Soc. 2006 Jun;3(4):330-8. Review.

PMID:
16738197
[PubMed - indexed for MEDLINE]
14.

Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis.

Wu MJ, Wen MC, Chiu YT, Chiou YY, Shu KH, Tang MJ.

Kidney Int. 2006 Jun;69(11):2029-36.

PMID:
16732193
[PubMed - indexed for MEDLINE]
15.

Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors.

Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE.

Genes Dev. 2006 Jun 1;20(11):1496-510. Epub 2006 May 16.

PMID:
16705038
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Involvement of H- and N-Ras isoforms in transforming growth factor-beta1-induced proliferation and in collagen and fibronectin synthesis.

Martínez-Salgado C, Fuentes-Calvo I, García-Cenador B, Santos E, López-Novoa JM.

Exp Cell Res. 2006 Jul 1;312(11):2093-106. Epub 2006 Apr 19.

PMID:
16624289
[PubMed - indexed for MEDLINE]
17.

Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats.

Lloberas N, Cruzado JM, Franquesa M, Herrero-Fresneda I, Torras J, Alperovich G, Rama I, Vidal A, Grinyó JM.

J Am Soc Nephrol. 2006 May;17(5):1395-404. Epub 2006 Apr 5.

PMID:
16597691
[PubMed - indexed for MEDLINE]
Free Article
18.

Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.

Zanesi N, Aqeilan R, Drusco A, Kaou M, Sevignani C, Costinean S, Bortesi L, La Rocca G, Koldovsky P, Volinia S, Mancini R, Calin G, Scott CP, Pekarsky Y, Croce CM.

Cancer Res. 2006 Jan 15;66(2):915-20.

PMID:
16424025
[PubMed - indexed for MEDLINE]
Free Article
19.

[Successful treatment of a severe case of idiopathic pulmonary fibrosis with rapamycin].

Buschhausen L, Kamm M, Arns W, Schulze-Lohoff E, Weber M.

Med Klin (Munich). 2005 Mar 15;100(3):161-4. German.

PMID:
15966446
[PubMed - indexed for MEDLINE]
20.

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.

Abdollahi A, Li M, Ping G, Plathow C, Domhan S, Kiessling F, Lee LB, McMahon G, Gröne HJ, Lipson KE, Huber PE.

J Exp Med. 2005 Mar 21;201(6):925-35.

PMID:
15781583
[PubMed - indexed for MEDLINE]
Free PMC Article
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