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Items: 1 to 20 of 33


Regulation of the proapoptotic factor Bax by Ku70-dependent deubiquitylation.

Amsel AD, Rathaus M, Kronman N, Cohen HY.

Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5117-22. doi: 10.1073/pnas.0706700105. Epub 2008 Mar 24.


Autocrine IL-6 signaling: a key event in tumorigenesis?

Grivennikov S, Karin M.

Cancer Cell. 2008 Jan;13(1):7-9. doi: 10.1016/j.ccr.2007.12.020.


Clusterin mediates TRAIL resistance in prostate tumor cells.

Sallman DA, Chen X, Zhong B, Gilvary DL, Zhou J, Wei S, Djeu JY.

Mol Cancer Ther. 2007 Nov;6(11):2938-47.


Therapeutic strategies for targeting the IL-6/STAT3 cytokine signaling pathway in inflammatory bowel disease.

Mitsuyama K, Matsumoto S, Masuda J, Yamasakii H, Kuwaki K, Takedatsu H, Sata M.

Anticancer Res. 2007 Nov-Dec;27(6A):3749-56. Review.


Cancer. Sex, cytokines, and cancer.

Lawrence T, Hageman T, Balkwill F.

Science. 2007 Jul 6;317(5834):51-2. No abstract available.


Mechanism and therapeutic reversal of immune suppression in cancer.

Herber DL, Nagaraj S, Djeu JY, Gabrilovich DI.

Cancer Res. 2007 Jun 1;67(11):5067-9. No abstract available.


Concentrations of TIMP1 mRNA splice variants and TIMP-1 protein are differentially associated with prognosis in primary breast cancer.

Sieuwerts AM, Usher PA, Meijer-van Gelder ME, Timmermans M, Martens JW, Brünner N, Klijn JG, Offenberg H, Foekens JA.

Clin Chem. 2007 Jul;53(7):1280-8. Epub 2007 May 3.


Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy.

Nash KT, Phadke PA, Navenot JM, Hurst DR, Accavitti-Loper MA, Sztul E, Vaidya KS, Frost AR, Kappes JC, Peiper SC, Welch DR.

J Natl Cancer Inst. 2007 Feb 21;99(4):309-21. Erratum in: J Natl Cancer Inst. 2007 Jul 20;99(12):977.


Interleukin-6 trans-signaling in inflammatory bowel disease.

Mitsuyama K, Sata M, Rose-John S.

Cytokine Growth Factor Rev. 2006 Dec;17(6):451-61. Epub 2006 Oct 12. Review.


Clusterin inhibits apoptosis by interacting with activated Bax.

Zhang H, Kim JK, Edwards CA, Xu Z, Taichman R, Wang CY.

Nat Cell Biol. 2005 Sep;7(9):909-15. Epub 2005 Aug 21.


Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth.

Corvinus FM, Orth C, Moriggl R, Tsareva SA, Wagner S, Pfitzner EB, Baus D, Kaufmann R, Huber LA, Zatloukal K, Beug H, Ohlschläger P, Schütz A, Halbhuber KJ, Friedrich K.

Neoplasia. 2005 Jun;7(6):545-55.


Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors.

Subramanian C, Opipari AW Jr, Bian X, Castle VP, Kwok RP.

Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4842-7. Epub 2005 Mar 18.


Delayed activation of insulin-like growth factor-1 receptor/Src/MAPK/Egr-1 signaling regulates clusterin expression, a pro-survival factor.

Criswell T, Beman M, Araki S, Leskov K, Cataldo E, Mayo LD, Boothman DA.

J Biol Chem. 2005 Apr 8;280(14):14212-21. Epub 2005 Feb 2.


The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin.

Pucci S, Bonanno E, Pichiorri F, Mazzarelli P, Spagnoli LG.

Eur J Histochem. 2004 Apr-Jun;48(2):103-10.


Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, Frye R, Ploegh H, Kessler BM, Sinclair DA.

Mol Cell. 2004 Mar 12;13(5):627-38.


Modulation of different clusterin isoforms in human colon tumorigenesis.

Pucci S, Bonanno E, Pichiorri F, Angeloni C, Spagnoli LG.

Oncogene. 2004 Mar 25;23(13):2298-304.


Synthesis and functional analyses of nuclear clusterin, a cell death protein.

Leskov KS, Klokov DY, Li J, Kinsella TJ, Boothman DA.

J Biol Chem. 2003 Mar 28;278(13):11590-600. Epub 2003 Jan 24.


Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death.

Yang CR, Leskov K, Hosley-Eberlein K, Criswell T, Pink JJ, Kinsella TJ, Boothman DA.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):5907-12.


The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations.

Ferguson DO, Sekiguchi JM, Chang S, Frank KM, Gao Y, DePinho RA, Alt FW.

Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6630-3.

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