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Results: 1 to 20 of 25

1.

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.

Kaelin WG Jr, Ratcliffe PJ.

Mol Cell. 2008 May 23;30(4):393-402. doi: 10.1016/j.molcel.2008.04.009. Review.

PMID:
18498744
[PubMed - indexed for MEDLINE]
Free Article
2.

The expression of hypoxia-inducible factor-1alpha in hepatitis B virus-related hepatocellular carcinoma: correlation with patients' prognosis and hepatitis B virus X protein.

Xie H, Song J, Liu K, Ji H, Shen H, Hu S, Yang G, Du Y, Zou X, Jin H, Yan L, Liu J, Fan D.

Dig Dis Sci. 2008 Dec;53(12):3225-33. doi: 10.1007/s10620-008-0296-9. Epub 2008 May 9.

PMID:
18465238
[PubMed - indexed for MEDLINE]
3.

Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study.

Vergis R, Corbishley CM, Norman AR, Bartlett J, Jhavar S, Borre M, Heeboll S, Horwich A, Huddart R, Khoo V, Eeles R, Cooper C, Sydes M, Dearnaley D, Parker C.

Lancet Oncol. 2008 Apr;9(4):342-51. doi: 10.1016/S1470-2045(08)70076-7. Epub 2008 Mar 17.

PMID:
18343725
[PubMed - indexed for MEDLINE]
Free Article
4.

HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion.

Du R, Lu KV, Petritsch C, Liu P, Ganss R, Passegué E, Song H, Vandenberg S, Johnson RS, Werb Z, Bergers G.

Cancer Cell. 2008 Mar;13(3):206-20. doi: 10.1016/j.ccr.2008.01.034.

PMID:
18328425
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sp1 transcription factor as a target for anthracyclines: effects on gene transcription.

Mansilla S, Portugal J.

Biochimie. 2008 Jul;90(7):976-87. doi: 10.1016/j.biochi.2007.12.008. Epub 2008 Jan 5. Review.

PMID:
18226599
[PubMed - indexed for MEDLINE]
6.

Evaluation of HIF-1 inhibitors as anticancer agents.

Semenza GL.

Drug Discov Today. 2007 Oct;12(19-20):853-9. Epub 2007 Sep 18. Review.

PMID:
17933687
[PubMed - indexed for MEDLINE]
7.

Effects of aging and hypoxia-inducible factor-1 activity on angiogenic cell mobilization and recovery of perfusion after limb ischemia.

Bosch-Marce M, Okuyama H, Wesley JB, Sarkar K, Kimura H, Liu YV, Zhang H, Strazza M, Rey S, Savino L, Zhou YF, McDonald KR, Na Y, Vandiver S, Rabi A, Shaked Y, Kerbel R, Lavallee T, Semenza GL.

Circ Res. 2007 Dec 7;101(12):1310-8. Epub 2007 Oct 11.

PMID:
17932327
[PubMed - indexed for MEDLINE]
Free Article
8.

Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.

Baek JH, Liu YV, McDonald KR, Wesley JB, Hubbi ME, Byun H, Semenza GL.

J Biol Chem. 2007 Aug 10;282(32):23572-80. Epub 2007 Jun 8.

PMID:
17558023
[PubMed - indexed for MEDLINE]
Free Article
9.

Cisplatin and doxorubicin repress Vascular Endothelial Growth Factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells.

Duyndam MC, van Berkel MP, Dorsman JC, Rockx DA, Pinedo HM, Boven E.

Biochem Pharmacol. 2007 Jul 15;74(2):191-201. Epub 2007 Apr 6.

PMID:
17498666
[PubMed - indexed for MEDLINE]
10.

Inhibition of angiogenesis by the antifungal drug itraconazole.

Chong CR, Xu J, Lu J, Bhat S, Sullivan DJ Jr, Liu JO.

ACS Chem Biol. 2007 Apr 24;2(4):263-70.

PMID:
17432820
[PubMed - indexed for MEDLINE]
11.

Targeting hypoxia cell signaling for cancer therapy.

Melillo G.

Cancer Metastasis Rev. 2007 Jun;26(2):341-52. Review.

PMID:
17415529
[PubMed - indexed for MEDLINE]
12.

Anthracyclines, small-molecule inhibitors of hypoxia-inducible factor-1 alpha activation.

Yamazaki Y, Hasebe Y, Egawa K, Nose K, Kunimoto S, Ikeda D.

Biol Pharm Bull. 2006 Oct;29(10):1999-2003.

PMID:
17015940
[PubMed - indexed for MEDLINE]
Free Article
13.

In vivo upregulation of CD95 and CD95L causes synergistic inhibition of angiogenesis by TSP1 peptide and metronomic doxorubicin treatment.

Quesada AJ, Nelius T, Yap R, Zaichuk TA, Alfranca A, Filleur S, Volpert OV, Redondo JM.

Cell Death Differ. 2005 Jun;12(6):649-58.

PMID:
15818399
[PubMed - indexed for MEDLINE]
Free Article
14.

Sequence specificity of formaldehyde-mediated covalent binding of anthracycline derivatives to DNA.

Szulawska A, Gniazdowski M, Czyz M.

Biochem Pharmacol. 2005 Jan 1;69(1):7-18.

PMID:
15588709
[PubMed - indexed for MEDLINE]
15.

Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy.

Drevs J, Fakler J, Eisele S, Medinger M, Bing G, Esser N, Marmé D, Unger C.

Anticancer Res. 2004 May-Jun;24(3a):1759-63.

PMID:
15274352
[PubMed - indexed for MEDLINE]
Free Article
16.

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1.

Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Kleinman ME, Capla JM, Galiano RD, Levine JP, Gurtner GC.

Nat Med. 2004 Aug;10(8):858-64. Epub 2004 Jul 4.

PMID:
15235597
[PubMed - indexed for MEDLINE]
17.

Oxygen-dependent asparagine hydroxylation.

Peet DJ, Lando D, Whelan DA, Whitelaw ML, Gorman JJ.

Methods Enzymol. 2004;381:467-87. No abstract available.

PMID:
15063693
[PubMed - indexed for MEDLINE]
18.

Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis.

Kim Y, Ma AG, Kitta K, Fitch SN, Ikeda T, Ihara Y, Simon AR, Evans T, Suzuki YJ.

Mol Pharmacol. 2003 Feb;63(2):368-77.

PMID:
12527808
[PubMed - indexed for MEDLINE]
Free Article
19.

DNA and its associated processes as targets for cancer therapy.

Hurley LH.

Nat Rev Cancer. 2002 Mar;2(3):188-200. Review.

PMID:
11990855
[PubMed - indexed for MEDLINE]
20.

Exploiting anthracycline scaffold for designing DNA-targeting agents.

Priebe W, Fokt I, Przewloka T, Chaires JB, Portugal J, Trent JO.

Methods Enzymol. 2001;340:529-55. No abstract available.

PMID:
11494869
[PubMed - indexed for MEDLINE]

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