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Items: 1 to 20 of 37

1.

Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis.

Meuer K, Suppanz IE, Lingor P, Planchamp V, Göricke B, Fichtner L, Braus GH, Dietz GP, Jakobs S, Bähr M, Weishaupt JH.

Cell Death Differ. 2007 Apr;14(4):651-61. Epub 2007 Jan 12.

2.

p53 downstream target genes and tumor suppression: a classical view in evolution.

Rozan LM, El-Deiry WS.

Cell Death Differ. 2007 Jan;14(1):3-9. Epub 2006 Oct 27. No abstract available.

3.

Topoisomerase I inhibitors: camptothecins and beyond.

Pommier Y.

Nat Rev Cancer. 2006 Oct;6(10):789-802. Review.

PMID:
16990856
4.

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo.

Pellegrini M, Celeste A, Difilippantonio S, Guo R, Wang W, Feigenbaum L, Nussenzweig A.

Nature. 2006 Sep 14;443(7108):222-5. Epub 2006 Aug 13.

PMID:
16906133
5.

DNA damage-induced cell death by apoptosis.

Roos WP, Kaina B.

Trends Mol Med. 2006 Sep;12(9):440-50. Epub 2006 Aug 8. Review.

PMID:
16899408
6.

Involvement of novel autophosphorylation sites in ATM activation.

Kozlov SV, Graham ME, Peng C, Chen P, Robinson PJ, Lavin MF.

EMBO J. 2006 Aug 9;25(15):3504-14. Epub 2006 Jul 13.

7.

Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.

Dupré A, Boyer-Chatenet L, Gautier J.

Nat Struct Mol Biol. 2006 May;13(5):451-7. Epub 2006 Apr 23.

PMID:
16622404
8.

A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM.

Sun Y, Jiang X, Chen S, Fernandes N, Price BD.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13182-7. Epub 2005 Sep 2.

9.

Involvement of human MOF in ATM function.

Gupta A, Sharma GG, Young CS, Agarwal M, Smith ER, Paull TT, Lucchesi JC, Khanna KK, Ludwig T, Pandita TK.

Mol Cell Biol. 2005 Jun;25(12):5292-305.

10.

Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2.

Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z.

J Neurosci. 2005 May 11;25(19):4823-34.

11.

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.

Falck J, Coates J, Jackson SP.

Nature. 2005 Mar 31;434(7033):605-11. Epub 2005 Mar 2.

PMID:
15758953
12.

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.

Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, Reaper PM, Jackson SP, Curtin NJ, Smith GC.

Cancer Res. 2004 Dec 15;64(24):9152-9.

13.

Divide and die: cell cycle events as triggers of nerve cell death.

Herrup K, Neve R, Ackerman SL, Copani A.

J Neurosci. 2004 Oct 20;24(42):9232-9. Review. No abstract available.

14.

ATM and ataxia telangiectasia.

McKinnon PJ.

EMBO Rep. 2004 Aug;5(8):772-6. Review.

15.

The retinoic acid and brain-derived neurotrophic factor differentiated SH-SY5Y cell line as a model for Alzheimer's disease-like tau phosphorylation.

Jämsä A, Hasslund K, Cowburn RF, Bäckström A, Vasänge M.

Biochem Biophys Res Commun. 2004 Jul 2;319(3):993-1000.

PMID:
15184080
16.

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway.

Kitagawa R, Bakkenist CJ, McKinnon PJ, Kastan MB.

Genes Dev. 2004 Jun 15;18(12):1423-38. Epub 2004 Jun 2.

17.

Cell cycle activation linked to neuronal cell death initiated by DNA damage.

Kruman II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, Chrest FJ, Emokpae R Jr, Gorospe M, Mattson MP.

Neuron. 2004 Feb 19;41(4):549-61.

18.

Requirement of the MRN complex for ATM activation by DNA damage.

Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y.

EMBO J. 2003 Oct 15;22(20):5612-21.

19.

Calpains mediate p53 activation and neuronal death evoked by DNA damage.

Sedarous M, Keramaris E, O'Hare M, Melloni E, Slack RS, Elce JS, Greer PA, Park DS.

J Biol Chem. 2003 Jul 11;278(28):26031-8. Epub 2003 Apr 29.

20.

Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis.

Gong X, Tang X, Wiedmann M, Wang X, Peng J, Zheng D, Blair LA, Marshall J, Mao Z.

Neuron. 2003 Apr 10;38(1):33-46.

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