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Items: 1 to 20 of 34


Adult T-cell progenitors retain myeloid potential.

Wada H, Masuda K, Satoh R, Kakugawa K, Ikawa T, Katsura Y, Kawamoto H.

Nature. 2008 Apr 10;452(7188):768-72. doi: 10.1038/nature06839.


The earliest thymic progenitors for T cells possess myeloid lineage potential.

Bell JJ, Bhandoola A.

Nature. 2008 Apr 10;452(7188):764-7. doi: 10.1038/nature06840.


Launching the T-cell-lineage developmental programme.

Rothenberg EV, Moore JE, Yui MA.

Nat Rev Immunol. 2008 Jan;8(1):9-21. Review.


Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway.

Tydell CC, David-Fung ES, Moore JE, Rowen L, Taghon T, Rothenberg EV.

J Immunol. 2007 Jul 1;179(1):421-38.


Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.

Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, DePinho RA.

Nature. 2007 Jun 21;447(7147):966-71. Epub 2007 May 21.


Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.

Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR.

Nature. 2007 Apr 12;446(7137):758-64.


Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95.

Schrauder A, Reiter A, Gadner H, Niethammer D, Klingebiel T, Kremens B, Peters C, Ebell W, Zimmermann M, Niggli F, Ludwig WD, Riehm H, Welte K, Schrappe M.

J Clin Oncol. 2006 Dec 20;24(36):5742-9.


High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults.

Baldus CD, Burmeister T, Martus P, Schwartz S, Gökbuget N, Bloomfield CD, Hoelzer D, Thiel E, Hofmann WK.

J Clin Oncol. 2006 Oct 10;24(29):4714-20. Epub 2006 Sep 5.


Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

Breit S, Stanulla M, Flohr T, Schrappe M, Ludwig WD, Tolle G, Happich M, Muckenthaler MU, Kulozik AE.

Blood. 2006 Aug 15;108(4):1151-7. Epub 2006 Apr 13.


Treatment of acute lymphoblastic leukemia.

Pui CH, Evans WE.

N Engl J Med. 2006 Jan 12;354(2):166-78. Review. No abstract available.


Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.

Weerkamp F, Baert MR, Brugman MH, Dik WA, de Haas EF, Visser TP, de Groot CJ, Wagemaker G, van Dongen JJ, Staal FJ.

Blood. 2006 Apr 15;107(8):3131-7. Epub 2005 Dec 29.


Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia.

Pui CH, Pei D, Sandlund JT, Campana D, Ribeiro RC, Razzouk BI, Rubnitz JE, Howard SC, Hijiya N, Jeha S, Cheng C, Downing JR, Evans WE, Relling MV, Hudson M.

J Clin Oncol. 2005 Nov 1;23(31):7936-41.


Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP.

Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15545-50. Epub 2005 Sep 30.


Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital.

Pui CH, Sandlund JT, Pei D, Campana D, Rivera GK, Ribeiro RC, Rubnitz JE, Razzouk BI, Howard SC, Hudson MM, Cheng C, Kun LE, Raimondi SC, Behm FG, Downing JR, Relling MV, Evans WE; Total Therapy Study XIIIB at St Jude Children's Research Hospital.

Blood. 2004 Nov 1;104(9):2690-6. Epub 2004 Jul 13.


Activating FLT3 mutations in CD117/KIT(+) T-cell acute lymphoblastic leukemias.

Paietta E, Ferrando AA, Neuberg D, Bennett JM, Racevskis J, Lazarus H, Dewald G, Rowe JM, Wiernik PH, Tallman MS, Look AT.

Blood. 2004 Jul 15;104(2):558-60. Epub 2004 Mar 25.


Notch regulation of lymphocyte development and function.

Radtke F, Wilson A, Mancini SJ, MacDonald HR.

Nat Immunol. 2004 Mar;5(3):247-53. Review.


Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia.

Ferrando AA, Neuberg DS, Dodge RK, Paietta E, Larson RA, Wiernik PH, Rowe JM, Caligiuri MA, Bloomfield CD, Look AT.

Lancet. 2004 Feb 14;363(9408):535-6.


Childhood T-cell acute lymphoblastic leukemia: the Dana-Farber Cancer Institute acute lymphoblastic leukemia consortium experience.

Goldberg JM, Silverman LB, Levy DE, Dalton VK, Gelber RD, Lehmann L, Cohen HJ, Sallan SE, Asselin BL.

J Clin Oncol. 2003 Oct 1;21(19):3616-22.


Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951.

Cavé H, Suciu S, Preudhomme C, Poppe B, Robert A, Uyttebroeck A, Malet M, Boutard P, Benoit Y, Mauvieux L, Lutz P, Méchinaud F, Grardel N, Mazingue F, Dupont M, Margueritte G, Pages MP, Bertrand Y, Plouvier E, Brunie G, Bastard C, Plantaz D, Vande Velde I, Hagemeijer A, Speleman F, Lessard M, Otten J, Vilmer E, Dastugue N; EORTC-CLG.

Blood. 2004 Jan 15;103(2):442-50. Epub 2003 Sep 22.

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