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Results: 1 to 20 of 45

1.

Plastin 3 is a protective modifier of autosomal recessive spinal muscular atrophy.

Oprea GE, Kröber S, McWhorter ML, Rossoll W, Müller S, Krawczak M, Bassell GJ, Beattie CE, Wirth B.

Science. 2008 Apr 25;320(5875):524-7. doi: 10.1126/science.1155085.

PMID:
18440926
[PubMed - indexed for MEDLINE]
Free Article
2.

A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy.

Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Bushby K, Escolar DM, Flanigan KM, Pestronk A, Tawil R, Wolfe GI, Eagle M, Florence JM, King WM, Pandya S, Straub V, Juneau P, Meyers K, Csimma C, Araujo T, Allen R, Parsons SA, Wozney JM, Lavallie ER, Mendell JR.

Ann Neurol. 2008 May;63(5):561-71. doi: 10.1002/ana.21338.

PMID:
18335515
[PubMed - indexed for MEDLINE]
3.

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors.

Haidet AM, Rizo L, Handy C, Umapathi P, Eagle A, Shilling C, Boue D, Martin PT, Sahenk Z, Mendell JR, Kaspar BK.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4318-22. doi: 10.1073/pnas.0709144105. Epub 2008 Mar 11.

PMID:
18334646
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

MuSK controls where motor axons grow and form synapses.

Kim N, Burden SJ.

Nat Neurosci. 2008 Jan;11(1):19-27. Epub 2007 Dec 16. Erratum in: Nat Neurosci. 2008 Feb;11(2):238.

PMID:
18084289
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Transforming growth factor-beta and myostatin signaling in skeletal muscle.

Kollias HD, McDermott JC.

J Appl Physiol (1985). 2008 Mar;104(3):579-87. Epub 2007 Nov 21. Review.

PMID:
18032576
[PubMed - indexed for MEDLINE]
Free Article
6.

Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer.

Tsuchida K, Nakatani M, Uezumi A, Murakami T, Cui X.

Endocr J. 2008 Mar;55(1):11-21. Epub 2007 Sep 14. Review.

PMID:
17878607
[PubMed - indexed for MEDLINE]
Free Article
7.

Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways.

Lee SJ.

PLoS One. 2007 Aug 29;2(8):e789.

PMID:
17726519
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Abnormal motor phenotype in the SMNDelta7 mouse model of spinal muscular atrophy.

Butchbach ME, Edwards JD, Burghes AH.

Neurobiol Dis. 2007 Aug;27(2):207-19. Epub 2007 May 5.

PMID:
17561409
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs.

Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA.

PLoS Genet. 2007 May 25;3(5):e79. Epub 2007 Apr 30.

PMID:
17530926
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

Handschin C, Kobayashi YM, Chin S, Seale P, Campbell KP, Spiegelman BM.

Genes Dev. 2007 Apr 1;21(7):770-83.

PMID:
17403779
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain 3 but not alpha-sarcoglycan deficiency.

Bartoli M, Poupiot J, Vulin A, Fougerousse F, Arandel L, Daniele N, Roudaut C, Noulet F, Garcia L, Danos O, Richard I.

Gene Ther. 2007 May;14(9):733-40. Epub 2007 Mar 1.

PMID:
17330087
[PubMed - indexed for MEDLINE]
12.

Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy.

Avila AM, Burnett BG, Taye AA, Gabanella F, Knight MA, Hartenstein P, Cizman Z, Di Prospero NA, Pellizzoni L, Fischbeck KH, Sumner CJ.

J Clin Invest. 2007 Mar;117(3):659-71. Epub 2007 Feb 22.

PMID:
17318264
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.

Miller TM, Kim SH, Yamanaka K, Hester M, Umapathi P, Arnson H, Rizo L, Mendell JR, Gage FH, Cleveland DW, Kaspar BK.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19546-51. Epub 2006 Dec 12.

PMID:
17164329
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Novel aminoglycosides increase SMN levels in spinal muscular atrophy fibroblasts.

Mattis VB, Rai R, Wang J, Chang CW, Coady T, Lorson CL.

Hum Genet. 2006 Nov;120(4):589-601. Epub 2006 Sep 2.

PMID:
16951947
[PubMed - indexed for MEDLINE]
15.

Regular exercise prolongs survival in a type 2 spinal muscular atrophy model mouse.

Grondard C, Biondi O, Armand AS, Lécolle S, Della Gaspera B, Pariset C, Li H, Gallien CL, Vidal PP, Chanoine C, Charbonnier F.

J Neurosci. 2005 Aug 17;25(33):7615-22. Erratum in: J Neurosci. 2005 Sep 14;25(37):8587.

PMID:
16107648
[PubMed - indexed for MEDLINE]
Free Article
16.

Synergy of insulin-like growth factor-1 and exercise in amyotrophic lateral sclerosis.

Kaspar BK, Frost LM, Christian L, Umapathi P, Gage FH.

Ann Neurol. 2005 May;57(5):649-55.

PMID:
15852403
[PubMed - indexed for MEDLINE]
17.

Myostatin propeptide-mediated amelioration of dystrophic pathophysiology.

Bogdanovich S, Perkins KJ, Krag TO, Whittemore LA, Khurana TS.

FASEB J. 2005 Apr;19(6):543-9.

PMID:
15791004
[PubMed - indexed for MEDLINE]
Free Article
18.

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN.

Le TT, Pham LT, Butchbach ME, Zhang HL, Monani UR, Coovert DD, Gavrilina TO, Xing L, Bassell GJ, Burghes AH.

Hum Mol Genet. 2005 Mar 15;14(6):845-57. Epub 2005 Feb 9.

PMID:
15703193
[PubMed - indexed for MEDLINE]
Free Article
19.

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model.

Dobrowolny G, Giacinti C, Pelosi L, Nicoletti C, Winn N, Barberi L, Molinaro M, Rosenthal N, Musarò A.

J Cell Biol. 2005 Jan 17;168(2):193-9.

PMID:
15657392
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Loss of myostatin expression alters fiber-type distribution and expression of myosin heavy chain isoforms in slow- and fast-type skeletal muscle.

Girgenrath S, Song K, Whittemore LA.

Muscle Nerve. 2005 Jan;31(1):34-40.

PMID:
15468312
[PubMed - indexed for MEDLINE]

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