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Results: 14

1.

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.

Hassane DC, Guzman ML, Corbett C, Li X, Abboud R, Young F, Liesveld JL, Carroll M, Jordan CT.

Blood. 2008 Jun 15;111(12):5654-62. doi: 10.1182/blood-2007-11-126003. Epub 2008 Feb 27.

PMID:
18305216
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.

Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT.

Blood. 2007 Dec 15;110(13):4427-35. Epub 2007 Sep 5.

PMID:
17804695
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8).

Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, H├ębert J, Young F, Jordan CT.

Blood. 2007 Dec 15;110(13):4436-44. Epub 2007 Sep 4.

PMID:
17785584
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia.

Hosen N, Park CY, Tatsumi N, Oji Y, Sugiyama H, Gramatzki M, Krensky AM, Weissman IL.

Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11008-13. Epub 2007 Jun 18.

PMID:
17576927
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Aberrant marker expression patterns on the CD34+CD38- stem cell compartment in acute myeloid leukemia allows to distinguish the malignant from the normal stem cell compartment both at diagnosis and in remission.

van Rhenen A, Moshaver B, Kelder A, Feller N, Nieuwint AW, Zweegman S, Ossenkoppele GJ, Schuurhuis GJ.

Leukemia. 2007 Aug;21(8):1700-7. Epub 2007 May 24.

PMID:
17525725
[PubMed - indexed for MEDLINE]
6.

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M.

Cancer Cell. 2006 Nov;10(5):375-88.

PMID:
17097560
[PubMed - indexed for MEDLINE]
Free Article
7.

Targeting of CD44 eradicates human acute myeloid leukemic stem cells.

Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE.

Nat Med. 2006 Oct;12(10):1167-74. Epub 2006 Sep 24.

PMID:
16998484
[PubMed - indexed for MEDLINE]
8.

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells.

Guzman ML, Rossi RM, Karnischky L, Li X, Peterson DR, Howard DS, Jordan CT.

Blood. 2005 Jun 1;105(11):4163-9. Epub 2005 Feb 1.

PMID:
15687234
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice.

Tavor S, Petit I, Porozov S, Avigdor A, Dar A, Leider-Trejo L, Shemtov N, Deutsch V, Naparstek E, Nagler A, Lapidot T.

Cancer Res. 2004 Apr 15;64(8):2817-24.

PMID:
15087398
[PubMed - indexed for MEDLINE]
Free Article
10.

Preferential induction of apoptosis for primary human leukemic stem cells.

Guzman ML, Swiderski CF, Howard DS, Grimes BA, Rossi RM, Szilvassy SJ, Jordan CT.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16220-5. Epub 2002 Nov 25.

PMID:
12451177
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.

Feuring-Buske M, Frankel AE, Alexander RL, Gerhard B, Hogge DE.

Cancer Res. 2002 Mar 15;62(6):1730-6.

PMID:
11912147
[PubMed - indexed for MEDLINE]
Free Article
12.

Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.

Guzman ML, Neering SJ, Upchurch D, Grimes B, Howard DS, Rizzieri DA, Luger SM, Jordan CT.

Blood. 2001 Oct 15;98(8):2301-7.

PMID:
11588023
[PubMed - indexed for MEDLINE]
Free Article
13.

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells.

Jordan CT, Upchurch D, Szilvassy SJ, Guzman ML, Howard DS, Pettigrew AL, Meyerrose T, Rossi R, Grimes B, Rizzieri DA, Luger SM, Phillips GL.

Leukemia. 2000 Oct;14(10):1777-84.

PMID:
11021753
[PubMed - indexed for MEDLINE]
14.

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice.

Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE.

Nature. 1994 Feb 17;367(6464):645-8.

PMID:
7509044
[PubMed - indexed for MEDLINE]

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