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Results: 1 to 20 of 63

1.

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination.

Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA.

Mol Cell. 2008 Jun 20;30(6):689-700. doi: 10.1016/j.molcel.2008.05.014.

PMID:
18570872
[PubMed - indexed for MEDLINE]
Free Article
2.

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.

Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, Benetatos CA, Chunduru SK, Condon SM, McKinlay M, Brink R, Leverkus M, Tergaonkar V, Schneider P, Callus BA, Koentgen F, Vaux DL, Silke J.

Cell. 2007 Nov 16;131(4):682-93.

PMID:
18022363
[PubMed - indexed for MEDLINE]
Free Article
3.

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.

Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, Zobel K, Dynek JN, Elliott LO, Wallweber HJ, Flygare JA, Fairbrother WJ, Deshayes K, Dixit VM, Vucic D.

Cell. 2007 Nov 16;131(4):669-81.

PMID:
18022362
[PubMed - indexed for MEDLINE]
Free Article
4.

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.

Petersen SL, Wang L, Yalcin-Chin A, Li L, Peyton M, Minna J, Harran P, Wang X.

Cancer Cell. 2007 Nov;12(5):445-56.

PMID:
17996648
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The inhibitor of apoptosis proteins as therapeutic targets in cancer.

Vucic D, Fairbrother WJ.

Clin Cancer Res. 2007 Oct 15;13(20):5995-6000. Review.

PMID:
17947460
[PubMed - indexed for MEDLINE]
Free Article
6.

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis.

Deniaud A, Sharaf el dein O, Maillier E, Poncet D, Kroemer G, Lemaire C, Brenner C.

Oncogene. 2008 Jan 10;27(3):285-99. Epub 2007 Aug 13.

PMID:
17700538
[PubMed - indexed for MEDLINE]
7.

ER stress triggers apoptosis by activating BH3-only protein Bim.

Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A.

Cell. 2007 Jun 29;129(7):1337-49.

PMID:
17604722
[PubMed - indexed for MEDLINE]
Free Article
8.

A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway.

Kazemi S, Mounir Z, Baltzis D, Raven JF, Wang S, Krishnamoorthy JL, Pluquet O, Pelletier J, Koromilas AE.

Mol Biol Cell. 2007 Sep;18(9):3635-44. Epub 2007 Jun 27.

PMID:
17596516
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Akt up- and down-regulation in response to endoplasmic reticulum stress.

Hosoi T, Hyoda K, Okuma Y, Nomura Y, Ozawa K.

Brain Res. 2007 Jun 4;1152:27-31. Epub 2007 Mar 24.

PMID:
17434462
[PubMed - indexed for MEDLINE]
10.

ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1.

Shiraishi H, Okamoto H, Yoshimura A, Yoshida H.

J Cell Sci. 2006 Oct 1;119(Pt 19):3958-66. Epub 2006 Sep 5.

PMID:
16954146
[PubMed - indexed for MEDLINE]
Free Article
11.

The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth.

Fels DR, Koumenis C.

Cancer Biol Ther. 2006 Jul;5(7):723-8. Epub 2006 Jul 1. Review.

PMID:
16861899
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53.

Li J, Lee B, Lee AS.

J Biol Chem. 2006 Mar 17;281(11):7260-70. Epub 2006 Jan 6.

PMID:
16407291
[PubMed - indexed for MEDLINE]
Free Article
14.

The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases.

Eckelman BP, Salvesen GS.

J Biol Chem. 2006 Feb 10;281(6):3254-60. Epub 2005 Dec 8.

PMID:
16339151
[PubMed - indexed for MEDLINE]
Free Article
15.

Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism.

Di Sano F, Ferraro E, Tufi R, Achsel T, Piacentini M, Cecconi F.

J Biol Chem. 2006 Feb 3;281(5):2693-700. Epub 2005 Nov 29.

PMID:
16317003
[PubMed - indexed for MEDLINE]
Free Article
16.

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth.

Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, Scheuner D, Kaufman RJ, Bell J, Ron D, Wouters BG, Koumenis C.

EMBO J. 2005 Oct 5;24(19):3470-81. Epub 2005 Sep 8.

PMID:
16148948
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The mammalian unfolded protein response.

Schröder M, Kaufman RJ.

Annu Rev Biochem. 2005;74:739-89. Review.

PMID:
15952902
[PubMed - indexed for MEDLINE]
18.

BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death.

Mathai JP, Germain M, Shore GC.

J Biol Chem. 2005 Jun 24;280(25):23829-36. Epub 2005 Apr 4.

PMID:
15809295
[PubMed - indexed for MEDLINE]
Free Article
19.

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

Scott FL, Denault JB, Riedl SJ, Shin H, Renatus M, Salvesen GS.

EMBO J. 2005 Feb 9;24(3):645-55. Epub 2005 Jan 13.

PMID:
15650747
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.

Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N, Harding HP, Ron D.

Mol Cell Biol. 2004 Dec;24(23):10161-8.

PMID:
15542827
[PubMed - indexed for MEDLINE]
Free PMC Article

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