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Items: 1 to 20 of 96

1.

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation.

Duda DM, Borg LA, Scott DC, Hunt HW, Hammel M, Schulman BA.

Cell. 2008 Sep 19;134(6):995-1006. doi: 10.1016/j.cell.2008.07.022.

2.

Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail.

Yamoah K, Oashi T, Sarikas A, Gazdoiu S, Osman R, Pan ZQ.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12230-5. doi: 10.1073/pnas.0806155105. Epub 2008 Aug 22.

3.

Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.

Lee I, Schindelin H.

Cell. 2008 Jul 25;134(2):268-78. doi: 10.1016/j.cell.2008.05.046.

4.

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.

Souphron J, Waddell MB, Paydar A, Tokgöz-Gromley Z, Roussel MF, Schulman BA.

Biochemistry. 2008 Aug 26;47(34):8961-9. doi: 10.1021/bi800604c. Epub 2008 Jul 25.

5.

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease.

Kraft C, Deplazes A, Sohrmann M, Peter M.

Nat Cell Biol. 2008 May;10(5):602-10. doi: 10.1038/ncb1723. Epub 2008 Apr 6.

PMID:
18391941
6.

NEDD8 acts as a 'molecular switch' defining the functional selectivity of VHL.

Russell RC, Ohh M.

EMBO Rep. 2008 May;9(5):486-91. doi: 10.1038/embor.2008.19. Epub 2008 Mar 7.

7.

Cullin-RING ubiquitin ligases: global regulation and activation cycles.

Bosu DR, Kipreos ET.

Cell Div. 2008 Feb 18;3:7. doi: 10.1186/1747-1028-3-7.

8.

Ribosomal proteins are targets for the NEDD8 pathway.

Xirodimas DP, Sundqvist A, Nakamura A, Shen L, Botting C, Hay RT.

EMBO Rep. 2008 Mar;9(3):280-6. doi: 10.1038/embor.2008.10. Epub 2008 Feb 15.

9.

Identification of conjugation specificity determinants unmasks vestigial preference for ubiquitin within the NEDD8 E2.

Huang DT, Zhuang M, Ayrault O, Schulman BA.

Nat Struct Mol Biol. 2008 Mar;15(3):280-7. doi: 10.1038/nsmb.1387. Epub 2008 Feb 10.

PMID:
18264111
10.

A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

Jones J, Wu K, Yang Y, Guerrero C, Nillegoda N, Pan ZQ, Huang L.

J Proteome Res. 2008 Mar;7(3):1274-87. doi: 10.1021/pr700749v. Epub 2008 Feb 5.

11.

Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.

Kurz T, Chou YC, Willems AR, Meyer-Schaller N, Hecht ML, Tyers M, Peter M, Sicheri F.

Mol Cell. 2008 Jan 18;29(1):23-35. doi: 10.1016/j.molcel.2007.12.012.

12.

Inhibition of APP intracellular domain (AICD) transcriptional activity via covalent conjugation with Nedd8.

Lee MR, Lee D, Shin SK, Kim YH, Choi CY.

Biochem Biophys Res Commun. 2008 Feb 22;366(4):976-81. Epub 2007 Dec 26.

PMID:
18096514
13.

NEDD8: a new ataxin-3 interactor.

Ferro A, Carvalho AL, Teixeira-Castro A, Almeida C, Tomé RJ, Cortes L, Rodrigues AJ, Logarinho E, Sequeiros J, Macedo-Ribeiro S, Maciel P.

Biochim Biophys Acta. 2007 Nov;1773(11):1619-27. Epub 2007 Aug 24.

14.

Altered pattern of Cul-1 protein expression and neddylation in human lung tumours: relationships with CAND1 and cyclin E protein levels.

Salon C, Brambilla E, Brambilla C, Lantuejoul S, Gazzeri S, Eymin B.

J Pathol. 2007 Nov;213(3):303-10.

PMID:
17823919
15.

Control of cell proliferation via elevated NEDD8 conjugation in oral squamous cell carcinoma.

Chairatvit K, Ngamkitidechakul C.

Mol Cell Biochem. 2007 Dec;306(1-2):163-9. Epub 2007 Jul 28.

PMID:
17660949
16.

Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold.

Burroughs AM, Balaji S, Iyer LM, Aravind L.

Biol Direct. 2007 Jul 2;2:18.

17.

Structural basis for the function of DCN-1 in protein Neddylation.

Yang X, Zhou J, Sun L, Wei Z, Gao J, Gong W, Xu RM, Rao Z, Liu Y.

J Biol Chem. 2007 Aug 24;282(34):24490-4. Epub 2007 Jun 26.

18.

Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution.

Frickel EM, Quesada V, Muething L, Gubbels MJ, Spooner E, Ploegh H, Artavanis-Tsakonas K.

Cell Microbiol. 2007 Jun;9(6):1601-10. Epub 2007 Feb 16.

PMID:
17371404
19.

PARC and CUL7 form atypical cullin RING ligase complexes.

Skaar JR, Florens L, Tsutsumi T, Arai T, Tron A, Swanson SK, Washburn MP, DeCaprio JA.

Cancer Res. 2007 Mar 1;67(5):2006-14.

20.

Role of ubiquitin- and Ubl-binding proteins in cell signaling.

Kirkin V, Dikic I.

Curr Opin Cell Biol. 2007 Apr;19(2):199-205. Epub 2007 Feb 15. Review.

PMID:
17303403
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