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Items: 1 to 20 of 121

1.

The complement anaphylatoxin C5a induces apoptosis in adrenomedullary cells during experimental sepsis.

Flierl MA, Rittirsch D, Chen AJ, Nadeau BA, Day DE, Sarma JV, Huber-Lang MS, Ward PA.

PLoS One. 2008 Jul 2;3(7):e2560. doi: 10.1371/journal.pone.0002560.

2.

Functions of the complement components C3 and C5 during sepsis.

Flierl MA, Rittirsch D, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ward PA.

FASEB J. 2008 Oct;22(10):3483-90. doi: 10.1096/fj.08-110595. Epub 2008 Jun 27.

3.

Functional roles for C5a receptors in sepsis.

Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Köhl J, Gerard C, Sarma JV, Ward PA.

Nat Med. 2008 May;14(5):551-7. doi: 10.1038/nm1753. Epub 2008 May 4.

4.

HMGB1: endogenous danger signaling.

Klune JR, Dhupar R, Cardinal J, Billiar TR, Tsung A.

Mol Med. 2008 Jul-Aug;14(7-8):476-84. doi: 10.2119/2008-00034.Klune. Review.

5.

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.

Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W.

Nature. 2008 Apr 3;452(7187):654-8. doi: 10.1038/nature06663. Epub 2008 Feb 27.

PMID:
18305483
6.

Adverse functions of IL-17A in experimental sepsis.

Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA.

FASEB J. 2008 Jul;22(7):2198-205. doi: 10.1096/fj.07-105221. Epub 2008 Feb 25.

7.

HMGB1 develops enhanced proinflammatory activity by binding to cytokines.

Sha Y, Zmijewski J, Xu Z, Abraham E.

J Immunol. 2008 Feb 15;180(4):2531-7.

8.

Host-pathogen interactions in sepsis.

van der Poll T, Opal SM.

Lancet Infect Dis. 2008 Jan;8(1):32-43. Epub 2007 Dec 11. Review.

PMID:
18063412
9.

'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage.

Kaneider NC, Leger AJ, Agarwal A, Nguyen N, Perides G, Derian C, Covic L, Kuliopulos A.

Nat Immunol. 2007 Dec;8(12):1303-12. Epub 2007 Oct 28.

10.

TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock.

Daubeuf B, Mathison J, Spiller S, Hugues S, Herren S, Ferlin W, Kosco-Vilbois M, Wagner H, Kirschning CJ, Ulevitch R, Elson G.

J Immunol. 2007 Nov 1;179(9):6107-14.

11.

Phagocyte-derived catecholamines enhance acute inflammatory injury.

Flierl MA, Rittirsch D, Nadeau BA, Chen AJ, Sarma JV, Zetoune FS, McGuire SR, List RP, Day DE, Hoesel LM, Gao H, Van Rooijen N, Huber-Lang MS, Neubig RR, Ward PA.

Nature. 2007 Oct 11;449(7163):721-5. Epub 2007 Sep 30.

PMID:
17914358
12.

Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis.

Huston JM, Gallowitsch-Puerta M, Ochani M, Ochani K, Yuan R, Rosas-Ballina M, Ashok M, Goldstein RS, Chavan S, Pavlov VA, Metz CN, Yang H, Czura CJ, Wang H, Tracey KJ.

Crit Care Med. 2007 Dec;35(12):2762-8.

PMID:
17901837
13.

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H.

J Exp Med. 2007 Oct 1;204(10):2439-48. Epub 2007 Sep 24.

14.

Adaptive immune cells temper initial innate responses.

Kim KD, Zhao J, Auh S, Yang X, Du P, Tang H, Fu YX.

Nat Med. 2007 Oct;13(10):1248-52. Epub 2007 Sep 23.

15.

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran.

Kim HM, Park BS, Kim JI, Kim SE, Lee J, Oh SC, Enkhbayar P, Matsushima N, Lee H, Yoo OJ, Lee JO.

Cell. 2007 Sep 7;130(5):906-17.

16.

Simultaneous activation of complement and coagulation by MBL-associated serine protease 2.

Krarup A, Wallis R, Presanis JS, Gál P, Sim RB.

PLoS One. 2007 Jul 18;2(7):e623.

17.

Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.

Ohto U, Fukase K, Miyake K, Satow Y.

Science. 2007 Jun 15;316(5831):1632-4.

18.

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

Dombrovskiy VY, Martin AA, Sunderram J, Paz HL.

Crit Care Med. 2007 May;35(5):1244-50.

PMID:
17414736
19.

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood.

Clark SR, Ma AC, Tavener SA, McDonald B, Goodarzi Z, Kelly MM, Patel KD, Chakrabarti S, McAvoy E, Sinclair GD, Keys EM, Allen-Vercoe E, Devinney R, Doig CJ, Green FH, Kubes P.

Nat Med. 2007 Apr;13(4):463-9. Epub 2007 Mar 25.

PMID:
17384648
20.

Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo.

Zhang X, Kimura Y, Fang C, Zhou L, Sfyroera G, Lambris JD, Wetsel RA, Miwa T, Song WC.

Blood. 2007 Jul 1;110(1):228-36. Epub 2007 Mar 15. Erratum in: Blood. 2007 Dec 1;110(12):3841.

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