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Results: 1 to 20 of 39

1.

Synthesis and Purification of Highly Hydrophobic Peptides Derived from the C-Terminus of Amyloid β-Protein.

Condron MM, Monien BH, Bitan G.

Open Biotechnol J. 2008 Jan 1;2(1):87-93.

PMID:
19898686
[PubMed]
Free PMC Article
2.

Forecasting the global burden of Alzheimer's disease.

Brookmeyer R, Johnson E, Ziegler-Graham K, Arrighi HM.

Alzheimers Dement. 2007 Jul;3(3):186-91. doi: 10.1016/j.jalz.2007.04.381.

PMID:
19595937
[PubMed]
3.

2008 Alzheimer's disease facts and figures.

Alzheimer's Association.

Alzheimers Dement. 2008 Mar;4(2):110-33. doi: 10.1016/j.jalz.2008.02.005.

PMID:
18631956
[PubMed - indexed for MEDLINE]
4.

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers.

Ehrnhoefer DE, Bieschke J, Boeddrich A, Herbst M, Masino L, Lurz R, Engemann S, Pastore A, Wanker EE.

Nat Struct Mol Biol. 2008 Jun;15(6):558-66. doi: 10.1038/nsmb.1437. Epub 2008 May 30.

PMID:
18511942
[PubMed - indexed for MEDLINE]
5.

Small-molecule aggregates inhibit amyloid polymerization.

Feng BY, Toyama BH, Wille H, Colby DW, Collins SR, May BC, Prusiner SB, Weissman J, Shoichet BK.

Nat Chem Biol. 2008 Mar;4(3):197-9. doi: 10.1038/nchembio.65. Epub 2008 Jan 27.

PMID:
18223646
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice.

Martins IC, Kuperstein I, Wilkinson H, Maes E, Vanbrabant M, Jonckheere W, Van Gelder P, Hartmann D, D'Hooge R, De Strooper B, Schymkowitz J, Rousseau F.

EMBO J. 2008 Jan 9;27(1):224-33. Epub 2007 Dec 6.

PMID:
18059472
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

The Alzheimer's peptides Abeta40 and 42 adopt distinct conformations in water: a combined MD / NMR study.

Sgourakis NG, Yan Y, McCallum SA, Wang C, Garcia AE.

J Mol Biol. 2007 May 18;368(5):1448-57. Epub 2007 Mar 7.

PMID:
17397862
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function.

Parameshwaran K, Sims C, Kanju P, Vaithianathan T, Shonesy BC, Dhanasekaran M, Bahr BA, Suppiramaniam V.

Synapse. 2007 Jun;61(6):367-74.

PMID:
17372971
[PubMed - indexed for MEDLINE]
10.

Role of electrostatic interactions in amyloid beta-protein (A beta) oligomer formation: a discrete molecular dynamics study.

Yun S, Urbanc B, Cruz L, Bitan G, Teplow DB, Stanley HE.

Biophys J. 2007 Jun 1;92(11):4064-77. Epub 2007 Feb 16.

PMID:
17307823
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A beta oligomers - a decade of discovery.

Walsh DM, Selkoe DJ.

J Neurochem. 2007 Jun;101(5):1172-84. Epub 2007 Feb 5. Review.

PMID:
17286590
[PubMed - indexed for MEDLINE]
12.

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.

Necula M, Kayed R, Milton S, Glabe CG.

J Biol Chem. 2007 Apr 6;282(14):10311-24. Epub 2007 Feb 6.

PMID:
17284452
[PubMed - indexed for MEDLINE]
Free Article
13.

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

Haass C, Selkoe DJ.

Nat Rev Mol Cell Biol. 2007 Feb;8(2):101-12. Review.

PMID:
17245412
[PubMed - indexed for MEDLINE]
14.

Ab initio discrete molecular dynamics approach to protein folding and aggregation.

Urbanc B, Borreguero JM, Cruz L, Stanley HE.

Methods Enzymol. 2006;412:314-38. Review.

PMID:
17046666
[PubMed - indexed for MEDLINE]
15.
16.

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

McLaurin J, Kierstead ME, Brown ME, Hawkes CA, Lambermon MH, Phinney AL, Darabie AA, Cousins JE, French JE, Lan MF, Chen F, Wong SS, Mount HT, Fraser PE, Westaway D, St George-Hyslop P.

Nat Med. 2006 Jul;12(7):801-8. Epub 2006 Jun 11.

PMID:
16767098
[PubMed - indexed for MEDLINE]
17.

Quasielastic light scattering study of amyloid beta-protein fibril formation.

Lomakin A, Teplow DB.

Protein Pept Lett. 2006;13(3):247-54. Review.

PMID:
16515452
[PubMed - indexed for MEDLINE]
18.

Structure of amyloid beta fragments in aqueous environments.

Takano K, Endo S, Mukaiyama A, Chon H, Matsumura H, Koga Y, Kanaya S.

FEBS J. 2006 Jan;273(1):150-8.

PMID:
16367755
[PubMed - indexed for MEDLINE]
19.

Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease.

Murakami K, Irie K, Ohigashi H, Hara H, Nagao M, Shimizu T, Shirasawa T.

J Am Chem Soc. 2005 Nov 2;127(43):15168-74.

PMID:
16248658
[PubMed - indexed for MEDLINE]
20.

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, Delucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T.

Neuron. 2005 Jul 21;47(2):191-9.

PMID:
16039562
[PubMed - indexed for MEDLINE]
Free PMC Article

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