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Results: 1 to 20 of 60

1.

microRNAs join the p53 network--another piece in the tumour-suppression puzzle.

He L, He X, Lowe SW, Hannon GJ.

Nat Rev Cancer. 2007 Nov;7(11):819-22. Review.

PMID:
17914404
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells.

Tazawa H, Tsuchiya N, Izumiya M, Nakagama H.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15472-7. Epub 2007 Sep 17.

PMID:
17875987
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

SIRT1 is significantly elevated in mouse and human prostate cancer.

Huffman DM, Grizzle WE, Bamman MM, Kim JS, Eltoum IA, Elgavish A, Nagy TR.

Cancer Res. 2007 Jul 15;67(14):6612-8. Erratum in: Cancer Res. 2007 Sep 1;67(17):8423.

PMID:
17638871
[PubMed - indexed for MEDLINE]
Free Article
4.

A microRNA component of the p53 tumour suppressor network.

He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ.

Nature. 2007 Jun 28;447(7148):1130-4. Epub 2007 Jun 6.

PMID:
17554337
[PubMed - indexed for MEDLINE]
5.

Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.

Tarasov V, Jung P, Verdoodt B, Lodygin D, Epanchintsev A, Menssen A, Meister G, Hermeking H.

Cell Cycle. 2007 Jul 1;6(13):1586-93. Epub 2007 May 11.

PMID:
17554199
[PubMed - indexed for MEDLINE]
Free Article
6.

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis.

Chang TC, Wentzel EA, Kent OA, Ramachandran K, Mullendore M, Lee KH, Feldmann G, Yamakuchi M, Ferlito M, Lowenstein CJ, Arking DE, Beer MA, Maitra A, Mendell JT.

Mol Cell. 2007 Jun 8;26(5):745-52. Epub 2007 May 31.

PMID:
17540599
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis.

Raver-Shapira N, Marciano E, Meiri E, Spector Y, Rosenfeld N, Moskovits N, Bentwich Z, Oren M.

Mol Cell. 2007 Jun 8;26(5):731-43. Epub 2007 May 31.

PMID:
17540598
[PubMed - indexed for MEDLINE]
Free Article
8.

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation.

Mayr C, Hemann MT, Bartel DP.

Science. 2007 Mar 16;315(5818):1576-9. Epub 2007 Feb 22.

PMID:
17322030
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells.

Welch C, Chen Y, Stallings RL.

Oncogene. 2007 Jul 26;26(34):5017-22. Epub 2007 Feb 12.

PMID:
17297439
[PubMed - indexed for MEDLINE]
10.

Strong expression of a longevity-related protein, SIRT1, in Bowen's disease.

Hida Y, Kubo Y, Murao K, Arase S.

Arch Dermatol Res. 2007 May;299(2):103-6. Epub 2006 Dec 20.

PMID:
17180656
[PubMed - indexed for MEDLINE]
11.

Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181.

Pekarsky Y, Santanam U, Cimmino A, Palamarchuk A, Efanov A, Maximov V, Volinia S, Alder H, Liu CG, Rassenti L, Calin GA, Hagan JP, Kipps T, Croce CM.

Cancer Res. 2006 Dec 15;66(24):11590-3.

PMID:
17178851
[PubMed - indexed for MEDLINE]
Free Article
12.

Array CGH analysis in primary gastrointestinal stromal tumors: cytogenetic profile correlates with anatomic site and tumor aggressiveness, irrespective of mutational status.

Wozniak A, Sciot R, Guillou L, Pauwels P, Wasag B, Stul M, Vermeesch JR, Vandenberghe P, Limon J, Debiec-Rychter M.

Genes Chromosomes Cancer. 2007 Mar;46(3):261-76.

PMID:
17171690
[PubMed - indexed for MEDLINE]
13.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Haigis MC, Guarente LP.

Genes Dev. 2006 Nov 1;20(21):2913-21. Review.

PMID:
17079682
[PubMed - indexed for MEDLINE]
Free Article
14.

Sirtuins in aging and age-related disease.

Longo VD, Kennedy BK.

Cell. 2006 Jul 28;126(2):257-68. Review.

PMID:
16873059
[PubMed - indexed for MEDLINE]
Free Article
15.

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes.

Heltweg B, Gatbonton T, Schuler AD, Posakony J, Li H, Goehle S, Kollipara R, Depinho RA, Gu Y, Simon JA, Bedalov A.

Cancer Res. 2006 Apr 15;66(8):4368-77.

PMID:
16618762
[PubMed - indexed for MEDLINE]
Free Article
16.

MicroRNAs as a potential magic bullet in cancer.

Slack FJ, Weidhaas JB.

Future Oncol. 2006 Feb;2(1):73-82. Review.

PMID:
16556074
[PubMed - indexed for MEDLINE]
17.

Chromosomal alterations in lung metastases of colorectal carcinomas: associations with tissue specific tumor dissemination.

Knösel T, Schlüns K, Dietel M, Petersen I.

Clin Exp Metastasis. 2005;22(7):533-8. Epub 2006 Feb 11.

PMID:
16475023
[PubMed - indexed for MEDLINE]
18.

A microRNA expression signature of human solid tumors defines cancer gene targets.

Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM.

Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2257-61. Epub 2006 Feb 3.

PMID:
16461460
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.

Chen WY, Wang DH, Yen RC, Luo J, Gu W, Baylin SB.

Cell. 2005 Nov 4;123(3):437-48.

PMID:
16269335
[PubMed - indexed for MEDLINE]
Free Article
20.

Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells.

Ota H, Tokunaga E, Chang K, Hikasa M, Iijima K, Eto M, Kozaki K, Akishita M, Ouchi Y, Kaneki M.

Oncogene. 2006 Jan 12;25(2):176-85.

PMID:
16170353
[PubMed - indexed for MEDLINE]
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