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Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases.

Lahm A, Paolini C, Pallaoro M, Nardi MC, Jones P, Neddermann P, Sambucini S, Bottomley MJ, Lo Surdo P, Carfí A, Koch U, De Francesco R, Steinkühler C, Gallinari P.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17335-40. Epub 2007 Oct 23.


Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.

Montgomery RL, Davis CA, Potthoff MJ, Haberland M, Fielitz J, Qi X, Hill JA, Richardson JA, Olson EN.

Genes Dev. 2007 Jul 15;21(14):1790-802.


Histone deacetylase inhibitors in cancer therapy.

Rasheed WK, Johnstone RW, Prince HM.

Expert Opin Investig Drugs. 2007 May;16(5):659-78. Review.


Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: implications for therapy.

Khabele D, Son DS, Parl AK, Goldberg GL, Augenlicht LH, Mariadason JM, Rice VM.

Cancer Biol Ther. 2007 May;6(5):795-801. Epub 2007 Feb 14.


Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression.

Escaffit F, Vaute O, Chevillard-Briet M, Segui B, Takami Y, Nakayama T, Trouche D.

Mol Cell Biol. 2007 Jan;27(2):554-67. Epub 2006 Nov 13.


Anticancer activities of histone deacetylase inhibitors.

Bolden JE, Peart MJ, Johnstone RW.

Nat Rev Drug Discov. 2006 Sep;5(9):769-84. Review.


Bcl-2 protein in 518A2 melanoma cells in vivo and in vitro.

Benimetskaya L, Ayyanar K, Kornblum N, Castanotto D, Rossi J, Wu S, Lai J, Brown BD, Popova N, Miller P, McMicken H, Chen Y, Stein CA.

Clin Cancer Res. 2006 Aug 15;12(16):4940-8.


New p53 related genes in human tumors: significant downregulation in colon and lung carcinomas.

LLeonart ME, Vidal F, Gallardo D, Diaz-Fuertes M, Rojo F, Cuatrecasas M, López-Vicente L, Kondoh H, Blanco C, Carnero A, Ramón y Cajal S.

Oncol Rep. 2006 Sep;16(3):603-8.


Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.

Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM.

J Biol Chem. 2006 May 12;281(19):13548-58. Epub 2006 Mar 13.


DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines.

Basile V, Mantovani R, Imbriano C.

J Biol Chem. 2006 Jan 27;281(4):2347-57. Epub 2005 Nov 17.


Acetylation and deacetylation of non-histone proteins.

Glozak MA, Sengupta N, Zhang X, Seto E.

Gene. 2005 Dec 19;363:15-23. Epub 2005 Nov 11. Review.


Regulation of histone deacetylase 4 expression by the SP family of transcription factors.

Liu F, Pore N, Kim M, Voong KR, Dowling M, Maity A, Kao GD.

Mol Biol Cell. 2006 Feb;17(2):585-97. Epub 2005 Nov 9.


Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death.

Bolger TA, Yao TP.

J Neurosci. 2005 Oct 12;25(41):9544-53.


Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors.

Codina A, Love JD, Li Y, Lazar MA, Neuhaus D, Schwabe JW.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6009-14. Epub 2005 Apr 18.


Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

Imbriano C, Gurtner A, Cocchiarella F, Di Agostino S, Basile V, Gostissa M, Dobbelstein M, Del Sal G, Piaggio G, Mantovani R.

Mol Cell Biol. 2005 May;25(9):3737-51.


Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis.

Mariadason JM, Nicholas C, L'Italien KE, Zhuang M, Smartt HJ, Heerdt BG, Yang W, Corner GA, Wilson AJ, Klampfer L, Arango D, Augenlicht LH.

Gastroenterology. 2005 Apr;128(4):1081-8.


Class II histone deacetylases: from sequence to function, regulation, and clinical implication.

Yang XJ, Grégoire S.

Mol Cell Biol. 2005 Apr;25(8):2873-84. Review. No abstract available.


Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1.

Huang BH, Laban M, Leung CH, Lee L, Lee CK, Salto-Tellez M, Raju GC, Hooi SC.

Cell Death Differ. 2005 Apr;12(4):395-404.


Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells.

Waltregny D, North B, Van Mellaert F, de Leval J, Verdin E, Castronovo V.

Eur J Histochem. 2004 Jul-Sep;48(3):273-90.

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