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Results: 12

1.

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J.

J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26.

PMID:
18363348
[PubMed - indexed for MEDLINE]
2.

Fluorescence spectroscopic profiling of compound libraries.

Simeonov A, Jadhav A, Thomas CJ, Wang Y, Huang R, Southall NT, Shinn P, Smith J, Austin CP, Auld DS, Inglese J.

J Med Chem. 2008 Apr 24;51(8):2363-71. doi: 10.1021/jm701301m. Epub 2008 Mar 26.

PMID:
18363325
[PubMed - indexed for MEDLINE]
3.

Identification of ligand binding by protein stabilization: comparison of ATLAS with biophysical and enzymatic methods.

Thompson PA, Wang S, Howett LJ, Wang MM, Patel R, Averill A, Showalter RE, Li B, Appleman JR.

Assay Drug Dev Technol. 2008 Feb;6(1):69-81. doi: 10.1089/adt.2007.100.

PMID:
18336087
[PubMed - indexed for MEDLINE]
4.

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS.

Nat Chem Biol. 2007 Aug;3(8):466-79. Review.

PMID:
17637779
[PubMed - indexed for MEDLINE]
5.

A high-throughput screen for aggregation-based inhibition in a large compound library.

Feng BY, Simeonov A, Jadhav A, Babaoglu K, Inglese J, Shoichet BK, Austin CP.

J Med Chem. 2007 May 17;50(10):2385-90. Epub 2007 Apr 21.

PMID:
17447748
[PubMed - indexed for MEDLINE]
6.

Bioluminescent assays for high-throughput screening.

Fan F, Wood KV.

Assay Drug Dev Technol. 2007 Feb;5(1):127-36. Review.

PMID:
17355205
[PubMed - indexed for MEDLINE]
7.

Radial clustergrams: visualizing the aggregate properties of hierarchical clusters.

Agrafiotis DK, Bandyopadhyay D, Farnum M.

J Chem Inf Model. 2007 Jan-Feb;47(1):69-75.

PMID:
17238250
[PubMed - indexed for MEDLINE]
8.

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. Epub 2006 Jul 24.

PMID:
16864780
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Development of a destabilized firefly luciferase enzyme for measurement of gene expression.

Leclerc GM, Boockfor FR, Faught WJ, Frawley LS.

Biotechniques. 2000 Sep;29(3):590-1, 594-6, 598 passim.

PMID:
10997273
[PubMed - indexed for MEDLINE]
10.

The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes.

Obrig TG, Culp WJ, McKeehan WL, Hardesty B.

J Biol Chem. 1971 Jan 10;246(1):174-81. No abstract available.

PMID:
5541758
[PubMed - indexed for MEDLINE]
Free Article
11.

The role of mRNA and protein stability in gene expression.

Hargrove JL, Schmidt FH.

FASEB J. 1989 Oct;3(12):2360-70. Review.

PMID:
2676679
[PubMed - indexed for MEDLINE]
Free Article
12.

Modulation of firefly luciferase stability and impact on studies of gene regulation.

Thompson JF, Hayes LS, Lloyd DB.

Gene. 1991 Jul 22;103(2):171-7.

PMID:
1889744
[PubMed - indexed for MEDLINE]

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