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Results: 1 to 20 of 87

1.
2.

Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.

Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W.

Gastroenterology. 2008 Feb;134(2):556-67. doi: 10.1053/j.gastro.2007.11.037. Epub 2007 Nov 28.

PMID:
18242221
[PubMed - indexed for MEDLINE]
3.

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma.

Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L, Shah B, Panopoulos AD, Schluns KS, Watowich SS, Tian Q, Jetten AM, Dong C.

Immunity. 2008 Jan;28(1):29-39. doi: 10.1016/j.immuni.2007.11.016. Epub 2007 Dec 27.

PMID:
18164222
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).

Wada T, Kang HS, Angers M, Gong H, Bhatia S, Khadem S, Ren S, Ellis E, Strom SC, Jetten AM, Xie W.

Mol Pharmacol. 2008 Mar;73(3):891-9. Epub 2007 Nov 30.

PMID:
18055760
[PubMed - indexed for MEDLINE]
Free Article
5.

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism.

Kang HS, Angers M, Beak JY, Wu X, Gimble JM, Wada T, Xie W, Collins JB, Grissom SF, Jetten AM.

Physiol Genomics. 2007 Oct 22;31(2):281-94. Epub 2007 Jul 31.

PMID:
17666523
[PubMed - indexed for MEDLINE]
Free Article
6.

Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor.

Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ, Song WC, Cheng SY, Xie W.

Mol Endocrinol. 2007 Aug;21(8):1781-90. Epub 2007 May 29.

PMID:
17536009
[PubMed - indexed for MEDLINE]
7.

Transcriptional coactivator PGC-1alpha integrates the mammalian clock and energy metabolism.

Liu C, Li S, Liu T, Borjigin J, Lin JD.

Nature. 2007 May 24;447(7143):477-81. Epub 2007 May 2.

PMID:
17476214
[PubMed - indexed for MEDLINE]
8.

Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.

Uppal H, Saini SP, Moschetta A, Mu Y, Zhou J, Gong H, Zhai Y, Ren S, Michalopoulos GK, Mangelsdorf DJ, Xie W.

Hepatology. 2007 Feb;45(2):422-32.

PMID:
17256725
[PubMed - indexed for MEDLINE]
9.

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR.

Cell. 2006 Sep 22;126(6):1121-33.

PMID:
16990136
[PubMed - indexed for MEDLINE]
Free Article
10.

Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation.

Jaradat M, Stapleton C, Tilley SL, Dixon D, Erikson CJ, McCaskill JG, Kang HS, Angers M, Liao G, Collins J, Grissom S, Jetten AM.

Am J Respir Crit Care Med. 2006 Dec 15;174(12):1299-309. Epub 2006 Sep 14.

PMID:
16973978
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

Srinivas M, Ng L, Liu H, Jia L, Forrest D.

Mol Endocrinol. 2006 Aug;20(8):1728-41. Epub 2006 Mar 30.

PMID:
16574740
[PubMed - indexed for MEDLINE]
12.

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.

Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W.

J Biol Chem. 2006 May 26;281(21):15013-20. Epub 2006 Mar 23.

PMID:
16556603
[PubMed - indexed for MEDLINE]
Free Article
13.

Expression of cytochrome P-450 4 enzymes in the kidney and liver: regulation by PPAR and species-difference between rat and human.

Ito O, Nakamura Y, Tan L, Ishizuka T, Sasaki Y, Minami N, Kanazawa M, Ito S, Sasano H, Kohzuki M.

Mol Cell Biochem. 2006 Mar;284(1-2):141-8. Epub 2006 Mar 22. Erratum in: Mol Cell Biochem. 2007 May;299(1-2):1-3.

PMID:
16552476
[PubMed - indexed for MEDLINE]
14.

Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.

Marschall HU, Wagner M, Bodin K, Zollner G, Fickert P, Gumhold J, Silbert D, Fuchsbichler A, Sjövall J, Trauner M.

J Lipid Res. 2006 Mar;47(3):582-92. Epub 2005 Dec 4.

PMID:
16327028
[PubMed - indexed for MEDLINE]
Free Article
15.

LXR deficiency and cholesterol feeding affect the expression and phenobarbital-mediated induction of cytochromes P450 in mouse liver.

Gnerre C, Schuster GU, Roth A, Handschin C, Johansson L, Looser R, Parini P, Podvinec M, Robertsson K, Gustafsson JA, Meyer UA.

J Lipid Res. 2005 Aug;46(8):1633-42. Epub 2005 Jun 1.

PMID:
15930522
[PubMed - indexed for MEDLINE]
Free Article
16.

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1.

Akashi M, Takumi T.

Nat Struct Mol Biol. 2005 May;12(5):441-8. Epub 2005 Apr 10.

PMID:
15821743
[PubMed - indexed for MEDLINE]
17.

Enhanced susceptibility of staggerer (RORalphasg/sg) mice to lipopolysaccharide-induced lung inflammation.

Stapleton CM, Jaradat M, Dixon D, Kang HS, Kim SC, Liao G, Carey MA, Cristiano J, Moorman MP, Jetten AM.

Am J Physiol Lung Cell Mol Physiol. 2005 Jul;289(1):L144-52. Epub 2005 Mar 18.

PMID:
15778248
[PubMed - indexed for MEDLINE]
Free Article
18.

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.

Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W.

Hepatology. 2005 Mar;41(3):497-505.

PMID:
15726644
[PubMed - indexed for MEDLINE]
19.

Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.

Stedman CA, Liddle C, Coulter SA, Sonoda J, Alvarez JG, Moore DD, Evans RM, Downes M.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2063-8. Epub 2005 Jan 31.

PMID:
15684063
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.

Uppal H, Toma D, Saini SP, Ren S, Jones TJ, Xie W.

Hepatology. 2005 Jan;41(1):168-76.

PMID:
15619241
[PubMed - indexed for MEDLINE]

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