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Results: 1 to 20 of 43

References for PMC Articles for PubMed (Select 18515545)

1.

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity.

Graff JR, Konicek BW, Vincent TM, Lynch RL, Monteith D, Weir SN, Schwier P, Capen A, Goode RL, Dowless MS, Chen Y, Zhang H, Sissons S, Cox K, McNulty AM, Parsons SH, Wang T, Sams L, Geeganage S, Douglass LE, Neubauer BL, Dean NM, Blanchard K, Shou J, Stancato LF, Carter JH, Marcusson EG.

J Clin Invest. 2007 Sep;117(9):2638-48.

2.

4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications.

Armengol G, Rojo F, Castellví J, Iglesias C, Cuatrecasas M, Pons B, Baselga J, Ramón y Cajal S.

Cancer Res. 2007 Aug 15;67(16):7551-5. Review.

3.

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2.

Le Bacquer O, Petroulakis E, Paglialunga S, Poulin F, Richard D, Cianflone K, Sonenberg N.

J Clin Invest. 2007 Feb;117(2):387-96.

4.

Stress and mTORture signaling.

Reiling JH, Sabatini DM.

Oncogene. 2006 Oct 16;25(48):6373-83. Review.

PMID:
17041623
5.

Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer.

Castellvi J, Garcia A, Rojo F, Ruiz-Marcellan C, Gil A, Baselga J, Ramon y Cajal S.

Cancer. 2006 Oct 15;107(8):1801-11.

6.

TOR signaling in growth and metabolism.

Wullschleger S, Loewith R, Hall MN.

Cell. 2006 Feb 10;124(3):471-84. Review.

7.

A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay.

Ferraiuolo MA, Basak S, Dostie J, Murray EL, Schoenberg DR, Sonenberg N.

J Cell Biol. 2005 Sep 12;170(6):913-24. Erratum in: J Cell Biol. 2005 Oct 10;171(1):175.

8.

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.

Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP.

Cell. 2005 Apr 22;121(2):179-93.

9.

eIF4E--from translation to transformation.

Mamane Y, Petroulakis E, Rong L, Yoshida K, Ler LW, Sonenberg N.

Oncogene. 2004 Apr 19;23(18):3172-9.

PMID:
15094766
10.
11.

mTOR integrates amino acid- and energy-sensing pathways.

Tokunaga C, Yoshino K, Yonezawa K.

Biochem Biophys Res Commun. 2004 Jan 9;313(2):443-6. Review.

PMID:
14684182
12.
13.

The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth.

Topisirovic I, Culjkovic B, Cohen N, Perez JM, Skrabanek L, Borden KL.

EMBO J. 2003 Feb 3;22(3):689-703.

14.

Real-time imaging of nuclear permeation by EGFP in single intact cells.

Wei X, Henke VG, Strübing C, Brown EB, Clapham DE.

Biophys J. 2003 Feb;84(2 Pt 1):1317-27.

15.

Localisation and regulation of the eIF4E-binding protein 4E-BP3.

Kleijn M, Scheper GC, Wilson ML, Tee AR, Proud CG.

FEBS Lett. 2002 Dec 18;532(3):319-23.

16.

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes.

Kimball SR, Horetsky RL, Ron D, Jefferson LS, Harding HP.

Am J Physiol Cell Physiol. 2003 Feb;284(2):C273-84. Epub 2002 Oct 3.

17.

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling.

Inoki K, Li Y, Zhu T, Wu J, Guan KL.

Nat Cell Biol. 2002 Sep;4(9):648-57.

PMID:
12172553
18.

Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture.

Zhang X, Shu L, Hosoi H, Murti KG, Houghton PJ.

J Biol Chem. 2002 Aug 2;277(31):28127-34. Epub 2002 May 8.

19.

Hierarchical phosphorylation of the translation inhibitor 4E-BP1.

Gingras AC, Raught B, Gygi SP, Niedzwiecka A, Miron M, Burley SK, Polakiewicz RD, Wyslouch-Cieszynska A, Aebersold R, Sonenberg N.

Genes Dev. 2001 Nov 1;15(21):2852-64.

20.

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

Tsukiyama-Kohara K, Poulin F, Kohara M, DeMaria CT, Cheng A, Wu Z, Gingras AC, Katsume A, Elchebly M, Spiegelman BM, Harper ME, Tremblay ML, Sonenberg N.

Nat Med. 2001 Oct;7(10):1128-32.

PMID:
11590436
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