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Results: 1 to 20 of 101

1.

A gain-of-function mutation in the HIF2A gene in familial erythrocytosis.

Percy MJ, Furlow PW, Lucas GS, Li X, Lappin TR, McMullin MF, Lee FS.

N Engl J Med. 2008 Jan 10;358(2):162-8. doi: 10.1056/NEJMoa073123.

PMID:
18184961
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity.

Kaluz S, Kaluzová M, Stanbridge EJ.

J Cell Biochem. 2008 May 15;104(2):536-44. Review.

PMID:
18059036
[PubMed - indexed for MEDLINE]
3.

RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia.

Carbia-Nagashima A, Gerez J, Perez-Castro C, Paez-Pereda M, Silberstein S, Stalla GK, Holsboer F, Arzt E.

Cell. 2007 Oct 19;131(2):309-23.

PMID:
17956732
[PubMed - indexed for MEDLINE]
Free Article
4.

Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney.

Kojima I, Tanaka T, Inagi R, Kato H, Yamashita T, Sakiyama A, Ohneda O, Takeda N, Sata M, Miyata T, Fujita T, Nangaku M.

J Am Soc Nephrol. 2007 Apr;18(4):1218-26. Epub 2007 Mar 7.

PMID:
17344427
[PubMed - indexed for MEDLINE]
Free Article
5.

Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.

Birle DC, Hedley DW.

Cancer Res. 2007 Feb 15;67(4):1735-43.

PMID:
17308115
[PubMed - indexed for MEDLINE]
Free Article
6.

Acute postnatal ablation of Hif-2alpha results in anemia.

Gruber M, Hu CJ, Johnson RS, Brown EJ, Keith B, Simon MC.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2301-6. Epub 2007 Feb 6.

PMID:
17284606
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

HIF-1alpha and EPAS ubiquitination mediated by the VHL tumour suppressor involves flexibility in the ubiquitination mechanism, similar to other RING E3 ligases.

Paltoglou S, Roberts BJ.

Oncogene. 2007 Jan 25;26(4):604-9. Epub 2006 Aug 21.

PMID:
16862177
[PubMed - indexed for MEDLINE]
8.
9.

Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.

Aprelikova O, Wood M, Tackett S, Chandramouli GV, Barrett JC.

Cancer Res. 2006 Jun 1;66(11):5641-7.

PMID:
16740701
[PubMed - indexed for MEDLINE]
Free Article
10.

Attenuation of oxidative stress in HL-1 cardiomyocytes improves mitochondrial function and stabilizes Hif-1alpha.

Vassilopoulos A, Papazafiri P.

Free Radic Res. 2005 Dec;39(12):1273-84.

PMID:
16298857
[PubMed - indexed for MEDLINE]
11.

The role of extracellular signal-regulated protein kinase in transcriptional regulation of the hypoxia marker carbonic anhydrase IX.

Kaluz S, Kaluzová M, Stanbridge EJ.

J Cell Biochem. 2006 Jan 1;97(1):207-16.

PMID:
16270297
[PubMed - indexed for MEDLINE]
12.

Integration of oxygen signaling at the consensus HRE.

Wenger RH, Stiehl DP, Camenisch G.

Sci STKE. 2005 Oct 18;2005(306):re12. Review.

PMID:
16234508
[PubMed - indexed for MEDLINE]
13.

Von Hippel-Lindau-dependent polycythemia is endemic on the island of Ischia: identification of a novel cluster.

Perrotta S, Nobili B, Ferraro M, Migliaccio C, Borriello A, Cucciolla V, Martinelli V, Rossi F, Punzo F, Cirillo P, Parisi G, Zappia V, Rotoli B, Della Ragione F.

Blood. 2006 Jan 15;107(2):514-9. Epub 2005 Oct 6.

PMID:
16210343
[PubMed - indexed for MEDLINE]
Free Article
14.

Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases.

Hirota K, Semenza GL.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):610-6. Epub 2005 Sep 2. Review.

PMID:
16154531
[PubMed - indexed for MEDLINE]
15.

Signalling hypoxia by HIF hydroxylases.

Schofield CJ, Ratcliffe PJ.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):617-26. Epub 2005 Aug 24. Review.

PMID:
16139242
[PubMed - indexed for MEDLINE]
16.

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability.

Isaacs JS, Jung YJ, Mole DR, Lee S, Torres-Cabala C, Chung YL, Merino M, Trepel J, Zbar B, Toro J, Ratcliffe PJ, Linehan WM, Neckers L.

Cancer Cell. 2005 Aug;8(2):143-53.

PMID:
16098467
[PubMed - indexed for MEDLINE]
Free Article
17.

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ.

Mol Cell Biol. 2005 Jul;25(13):5675-86.

PMID:
15964822
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression.

Kietzmann T, Görlach A.

Semin Cell Dev Biol. 2005 Aug-Oct;16(4-5):474-86. Review.

PMID:
15905109
[PubMed - indexed for MEDLINE]
19.

Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene.

Pescador N, Cuevas Y, Naranjo S, Alcaide M, Villar D, Landázuri MO, Del Peso L.

Biochem J. 2005 Aug 15;390(Pt 1):189-97.

PMID:
15823097
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.

Selak MA, Armour SM, MacKenzie ED, Boulahbel H, Watson DG, Mansfield KD, Pan Y, Simon MC, Thompson CB, Gottlieb E.

Cancer Cell. 2005 Jan;7(1):77-85.

PMID:
15652751
[PubMed - indexed for MEDLINE]
Free Article

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