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Structural basis for activation of fatty acid-binding protein 4.

Gillilan RE, Ayers SD, Noy N.

J Mol Biol. 2007 Oct 5;372(5):1246-60. Epub 2007 Aug 2.


Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.

Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.

Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.


Continuous nucleocytoplasmic shuttling underlies transcriptional activation of PPARgamma by FABP4.

Ayers SD, Nedrow KL, Gillilan RE, Noy N.

Biochemistry. 2007 Jun 12;46(23):6744-52. Epub 2007 May 22.


Tumor-suppressive activity of retinoic acid receptor-beta in cancer.

Xu XC.

Cancer Lett. 2007 Aug 8;253(1):14-24. Epub 2006 Dec 22. Review.


Crosstalk between peroxisome proliferator-activated receptor delta and VEGF stimulates cancer progression.

Wang D, Wang H, Guo Y, Ning W, Katkuri S, Wahli W, Desvergne B, Dey SK, DuBois RN.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19069-74. Epub 2006 Dec 5.


Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer.

Zhou Z, Flesken-Nikitin A, Corney DC, Wang W, Goodrich DW, Roy-Burman P, Nikitin AY.

Cancer Res. 2006 Aug 15;66(16):7889-98.


An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, Li C, Mitten MJ, Nettesheim DG, Ng S, Nimmer PM, O'Connor JM, Oleksijew A, Petros AM, Reed JC, Shen W, Tahir SK, Thompson CB, Tomaselli KJ, Wang B, Wendt MD, Zhang H, Fesik SW, Rosenberg SH.

Nature. 2005 Jun 2;435(7042):677-81. Epub 2005 May 15.


Retinoic acid receptors and cancers.

Soprano DR, Qin P, Soprano KJ.

Annu Rev Nutr. 2004;24:201-21. Review.


Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes.

Schmuth M, Haqq CM, Cairns WJ, Holder JC, Dorsam S, Chang S, Lau P, Fowler AJ, Chuang G, Moser AH, Brown BE, Mao-Qiang M, Uchida Y, Schoonjans K, Auwerx J, Chambon P, Willson TM, Elias PM, Feingold KR.

J Invest Dermatol. 2004 Apr;122(4):971-83. Erratum in: J Invest Dermatol. 2004 Oct;123(4):806.


Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.

Tan NS, Michalik L, Desvergne B, Wahli W.

Expert Opin Ther Targets. 2004 Feb;8(1):39-48. Review.


Retinoic acid is a high affinity selective ligand for the peroxisome proliferator-activated receptor beta/delta.

Shaw N, Elholm M, Noy N.

J Biol Chem. 2003 Oct 24;278(43):41589-92. Epub 2003 Sep 8.


Mammary carcinoma suppression by cellular retinoic acid binding protein-II.

Manor D, Shmidt EN, Budhu A, Flesken-Nikitin A, Zgola M, Page R, Nikitin AY, Noy N.

Cancer Res. 2003 Aug 1;63(15):4426-33.


Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice.

Nikitin AY, Liu CY, Flesken-Nikitin A, Chen CF, Chen PL, Lee WH.

Cancer Res. 2002 Sep 15;62(18):5134-8.


Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells.

Tari AM, Lim SJ, Hung MC, Esteva FJ, Lopez-Berestein G.

Oncogene. 2002 Aug 8;21(34):5224-32.


Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription.

Tan NS, Shaw NS, Vinckenbosch N, Liu P, Yasmin R, Desvergne B, Wahli W, Noy N.

Mol Cell Biol. 2002 Jul;22(14):5114-27. Erratum in: Mol Cell Biol 2002 Sep;22(17):6318.

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