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Results: 1 to 20 of 26

1.

Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer.

Koushik A, Kraft P, Fuchs CS, Hankinson SE, Willett WC, Giovannucci EL, Hunter DJ.

Cancer Epidemiol Biomarkers Prev. 2006 Dec;15(12):2408-17.

PMID:
17164363
[PubMed - indexed for MEDLINE]
Free Article
2.

Transcription factor 7-like 2 (TCF7L2) variant is associated with familial breast cancer risk: a case-control study.

Burwinkel B, Shanmugam KS, Hemminki K, Meindl A, Schmutzler RK, Sutter C, Wappenschmidt B, Kiechle M, Bartram CR, Frank B.

BMC Cancer. 2006 Nov 17;6:268.

PMID:
17109766
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

TCF7L2 and type 2 diabetes--we WNT to know.

Smith U.

Diabetologia. 2007 Jan;50(1):5-7. Epub 2006 Nov 11. No abstract available.

PMID:
17102948
[PubMed - indexed for MEDLINE]
4.

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.

Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC, Altshuler D.

Diabetes. 2006 Oct;55(10):2890-5.

PMID:
17003358
[PubMed - indexed for MEDLINE]
Free Article
5.

The consensus coding sequences of human breast and colorectal cancers.

Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.

Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7.

PMID:
16959974
[PubMed - indexed for MEDLINE]
Free Article
6.

Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

Damcott CM, Pollin TI, Reinhart LJ, Ott SH, Shen H, Silver KD, Mitchell BD, Shuldiner AR.

Diabetes. 2006 Sep;55(9):2654-9.

PMID:
16936218
[PubMed - indexed for MEDLINE]
Free Article
7.

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.

Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, Narisu N, Duren WL, Chines PS, Stringham HM, Erdos MR, Valle TT, Tuomilehto J, Bergman RN, Mohlke KL, Collins FS, Boehnke M.

Diabetes. 2006 Sep;55(9):2649-53.

PMID:
16936217
[PubMed - indexed for MEDLINE]
Free Article
8.

Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes in large cohorts of U.S. women and men.

Zhang C, Qi L, Hunter DJ, Meigs JB, Manson JE, van Dam RM, Hu FB.

Diabetes. 2006 Sep;55(9):2645-8.

PMID:
16936216
[PubMed - indexed for MEDLINE]
Free Article
9.

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI.

Diabetes. 2006 Sep;55(9):2640-4. Erratum in: Diabetes. 2006 Dec;55(12):3635.

PMID:
16936215
[PubMed - indexed for MEDLINE]
Free Article
10.

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.

Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, Shuldiner AR, Knowler WC, Nathan DM, Altshuler D; Diabetes Prevention Program Research Group.

N Engl J Med. 2006 Jul 20;355(3):241-50.

PMID:
16855264
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

C-peptide, insulin-like growth factor binding protein-1, glycosylated hemoglobin, and the risk of distal colorectal adenoma in women.

Wei EK, Ma J, Pollak MN, Rifai N, Fuchs CS, Hankinson SE, Giovannucci E.

Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):750-5.

PMID:
16614119
[PubMed - indexed for MEDLINE]
Free Article
12.

TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription.

Cuilliere-Dartigues P, El-Bchiri J, Krimi A, Buhard O, Fontanges P, Fléjou JF, Hamelin R, Duval A.

Oncogene. 2006 Jul 27;25(32):4441-8. Epub 2006 Mar 20.

PMID:
16547505
[PubMed - indexed for MEDLINE]
13.

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K.

Nat Genet. 2006 Mar;38(3):320-3. Epub 2006 Jan 15.

PMID:
16415884
[PubMed - indexed for MEDLINE]
14.

Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo.

Tran TT, Naigamwalla D, Oprescu AI, Lam L, McKeown-Eyssen G, Bruce WR, Giacca A.

Endocrinology. 2006 Apr;147(4):1830-7. Epub 2006 Jan 12.

PMID:
16410309
[PubMed - indexed for MEDLINE]
15.

APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenoma.

Tranah GJ, Giovannucci E, Ma J, Fuchs C, Hunter DJ.

Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):863-70.

PMID:
15824157
[PubMed - indexed for MEDLINE]
Free Article
16.

A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women.

Wei EK, Ma J, Pollak MN, Rifai N, Fuchs CS, Hankinson SE, Giovannucci E.

Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):850-5.

PMID:
15824155
[PubMed - indexed for MEDLINE]
Free Article
17.

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta.

Yi F, Brubaker PL, Jin T.

J Biol Chem. 2005 Jan 14;280(2):1457-64. Epub 2004 Nov 2.

PMID:
15525634
[PubMed - indexed for MEDLINE]
Free Article
18.

Convergence of Wnt, beta-catenin, and cadherin pathways.

Nelson WJ, Nusse R.

Science. 2004 Mar 5;303(5663):1483-7. Review.

PMID:
15001769
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Wnt signaling and cancer.

Polakis P.

Genes Dev. 2000 Aug 1;14(15):1837-51. Review. No abstract available.

PMID:
10921899
[PubMed - indexed for MEDLINE]
Free Article
20.

The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines.

Duval A, Rolland S, Tubacher E, Bui H, Thomas G, Hamelin R.

Cancer Res. 2000 Jul 15;60(14):3872-9.

PMID:
10919662
[PubMed - indexed for MEDLINE]
Free Article
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