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Items: 1 to 20 of 47

1.

A set of genes that regulate cell proliferation predicts treatment outcome in childhood acute lymphoblastic leukemia.

Flotho C, Coustan-Smith E, Pei D, Cheng C, Song G, Pui CH, Downing JR, Campana D.

Blood. 2007 Aug 15;110(4):1271-7. Epub 2007 Apr 24.

2.

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.

Wei G, Twomey D, Lamb J, Schlis K, Agarwal J, Stam RW, Opferman JT, Sallan SE, den Boer ML, Pieters R, Golub TR, Armstrong SA.

Cancer Cell. 2006 Oct;10(4):331-42. Epub 2006 Sep 28.

3.

A new mechanism of methotrexate action revealed by target screening with affinity beads.

Uga H, Kuramori C, Ohta A, Tsuboi Y, Tanaka H, Hatakeyama M, Yamaguchi Y, Takahashi T, Kizaki M, Handa H.

Mol Pharmacol. 2006 Nov;70(5):1832-9. Epub 2006 Aug 25.

4.

Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy.

Cheok MH, Evans WE.

Nat Rev Cancer. 2006 Feb;6(2):117-29. Review. Erratum in: Nat Rev Cancer. 2006 Mar;6(3):249.

PMID:
16491071
5.

Treatment of acute lymphoblastic leukemia.

Pui CH, Evans WE.

N Engl J Med. 2006 Jan 12;354(2):166-78. Review. No abstract available.

PMID:
16407512
6.

Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia.

Lugthart S, Cheok MH, den Boer ML, Yang W, Holleman A, Cheng C, Pui CH, Relling MV, Janka-Schaub GE, Pieters R, Evans WE.

Cancer Cell. 2005 Apr;7(4):375-86.

7.

Pharmacogenetics of outcome in children with acute lymphoblastic leukemia.

Rocha JC, Cheng C, Liu W, Kishi S, Das S, Cook EH, Sandlund JT, Rubnitz J, Ribeiro R, Campana D, Pui CH, Evans WE, Relling MV.

Blood. 2005 Jun 15;105(12):4752-8. Epub 2005 Feb 15.

8.

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.

Kager L, Cheok M, Yang W, Zaza G, Cheng Q, Panetta JC, Pui CH, Downing JR, Relling MV, Evans WE.

J Clin Invest. 2005 Jan;115(1):110-7.

9.

Bioconductor: open software development for computational biology and bioinformatics.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J.

Genome Biol. 2004;5(10):R80. Epub 2004 Sep 15.

10.

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia.

Cario G, Stanulla M, Fine BM, Teuffel O, Neuhoff NV, Schrauder A, Flohr T, Schäfer BW, Bartram CR, Welte K, Schlegelberger B, Schrappe M.

Blood. 2005 Jan 15;105(2):821-6. Epub 2004 Sep 23.

11.

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.

Holleman A, Cheok MH, den Boer ML, Yang W, Veerman AJ, Kazemier KM, Pei D, Cheng C, Pui CH, Relling MV, Janka-Schaub GE, Pieters R, Evans WE.

N Engl J Med. 2004 Aug 5;351(6):533-42.

12.

Moving towards individualized medicine with pharmacogenomics.

Evans WE, Relling MV.

Nature. 2004 May 27;429(6990):464-8. Review.

PMID:
15164072
13.

Rationale and design of Total Therapy Study XV for newly diagnosed childhood acute lymphoblastic leukemia.

Pui CH, Relling MV, Sandlund JT, Downing JR, Campana D, Evans WE.

Ann Hematol. 2004;83 Suppl 1:S124-6.

PMID:
15124703
14.

Acute lymphoblastic leukemia.

Pui CH, Relling MV, Downing JR.

N Engl J Med. 2004 Apr 8;350(15):1535-48. Review. No abstract available.

PMID:
15071128
15.

A global test for groups of genes: testing association with a clinical outcome.

Goeman JJ, van de Geer SA, de Kort F, van Houwelingen HC.

Bioinformatics. 2004 Jan 1;20(1):93-9.

16.

Results of therapy for acute lymphoblastic leukemia in black and white children.

Pui CH, Sandlund JT, Pei D, Rivera GK, Howard SC, Ribeiro RC, Rubnitz JE, Razzouk BI, Hudson MM, Cheng C, Raimondi SC, Behm FG, Downing JR, Relling MV, Evans WE.

JAMA. 2003 Oct 15;290(15):2001-7.

PMID:
14559953
17.

Reduced folate carrier and dihydrofolate reductase expression in acute lymphocytic leukemia may predict outcome: a Children's Cancer Group Study.

Levy AS, Sather HN, Steinherz PG, Sowers R, La M, Moscow JA, Gaynon PS, Uckun FM, Bertino JR, Gorlick R; Children's Cancer Group Study.

J Pediatr Hematol Oncol. 2003 Sep;25(9):688-95.

PMID:
12972803
18.

Extended follow-up of long-term survivors of childhood acute lymphoblastic leukemia.

Pui CH, Cheng C, Leung W, Rai SN, Rivera GK, Sandlund JT, Ribeiro RC, Relling MV, Kun LE, Evans WE, Hudson MM.

N Engl J Med. 2003 Aug 14;349(7):640-9. Erratum in: N Engl J Med. 2003 Sep 25;349(13):1299.

19.

Statistical significance for genomewide studies.

Storey JD, Tibshirani R.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9440-5. Epub 2003 Jul 25.

20.

Membrane transport of folates.

Matherly LH, Goldman DI.

Vitam Horm. 2003;66:403-56. Review.

PMID:
12852262
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