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Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates.

Matangkasombut P, Pichavant M, Yasumi T, Hendricks C, Savage PB, Dekruyff RH, Umetsu DT.

J Allergy Clin Immunol. 2008 May;121(5):1287-9. doi: 10.1016/j.jaci.2008.02.006. Epub 2008 Mar 19. No abstract available.


4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation.

Kim DH, Chang WS, Lee YS, Lee KA, Kim YK, Kwon BS, Kang CY.

J Immunol. 2008 Feb 15;180(4):2062-8.


Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17.

Pichavant M, Goya S, Meyer EH, Johnston RA, Kim HY, Matangkasombut P, Zhu M, Iwakura Y, Savage PB, DeKruyff RH, Shore SA, Umetsu DT.

J Exp Med. 2008 Feb 18;205(2):385-93. doi: 10.1084/jem.20071507. Epub 2008 Feb 4.


iNKT cells require CCR4 to localize to the airways and to induce airway hyperreactivity.

Meyer EH, Wurbel MA, Staton TL, Pichavant M, Kan MJ, Savage PB, DeKruyff RH, Butcher EC, Campbell JJ, Umetsu DT.

J Immunol. 2007 Oct 1;179(7):4661-71.


Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells.

Jin N, Miyahara N, Roark CL, French JD, Aydintug MK, Matsuda JL, Gapin L, O'Brien RL, Gelfand EW, Born WK.

J Immunol. 2007 Sep 1;179(5):2961-8.


Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease.

Vijayanand P, Seumois G, Pickard C, Powell RM, Angco G, Sammut D, Gadola SD, Friedmann PS, Djukanovic R.

N Engl J Med. 2007 Apr 5;356(14):1410-22.


CD4 engagement by CD1d potentiates activation of CD4+ invariant NKT cells.

Thedrez A, de Lalla C, Allain S, Zaccagnino L, Sidobre S, Garavaglia C, Borsellino G, Dellabona P, Bonneville M, Scotet E, Casorati G.

Blood. 2007 Jul 1;110(1):251-8. Epub 2007 Mar 15.


The biology of NKT cells.

Bendelac A, Savage PB, Teyton L.

Annu Rev Immunol. 2007;25:297-336. Review.


Activation of natural killer T cells by glycolipids.

Tupin E, Kronenberg M.

Methods Enzymol. 2006;417:185-201. Review.


CD28 and ICOS: similar or separate costimulators of T cells?

van Berkel ME, Oosterwegel MA.

Immunol Lett. 2006 Jun 15;105(2):115-22. Epub 2006 Mar 20. Review.


CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.

Akbari O, Faul JL, Hoyte EG, Berry GJ, Wahlström J, Kronenberg M, DeKruyff RH, Umetsu DT.

N Engl J Med. 2006 Mar 16;354(11):1117-29.


Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells.

Meyer EH, Goya S, Akbari O, Berry GJ, Savage PB, Kronenberg M, Nakayama T, DeKruyff RH, Umetsu DT.

Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2782-7. Epub 2006 Feb 14.


Functionally distinct NKT cell subsets and subtypes.

Seino K, Taniguchi M.

J Exp Med. 2005 Dec 19;202(12):1623-6.


Differential antitumor immunity mediated by NKT cell subsets in vivo.

Crowe NY, Coquet JM, Berzins SP, Kyparissoudis K, Keating R, Pellicci DG, Hayakawa Y, Godfrey DI, Smyth MJ.

J Exp Med. 2005 Nov 7;202(9):1279-88.


NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge.

Uldrich AP, Crowe NY, Kyparissoudis K, Pellicci DG, Zhan Y, Lew AM, Bouillet P, Strasser A, Smyth MJ, Godfrey DI.

J Immunol. 2005 Sep 1;175(5):3092-101.


ICOS contributes to T cell expansion in CTLA-4 deficient mice.

van Berkel ME, Schrijver EH, Hofhuis FM, Sharpe AH, Coyle AJ, Broeren CP, Tesselaar K, Oosterwegel MA.

J Immunol. 2005 Jul 1;175(1):182-8.


ICOS costimulates invariant NKT cell activation.

Kaneda H, Takeda K, Ota T, Kaduka Y, Akiba H, Ikarashi Y, Wakasugi H, Kronenberg M, Kinoshita K, Yagita H, Okumura K.

Biochem Biophys Res Commun. 2005 Feb 4;327(1):201-7.


Asthma is induced by intranasal coadministration of allergen and natural killer T-cell ligand in a mouse model.

Kim JO, Kim DH, Chang WS, Hong C, Park SH, Kim S, Kang CY.

J Allergy Clin Immunol. 2004 Dec;114(6):1332-8.

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