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Items: 1 to 20 of 56

1.

Understanding the benign nature of SIV infection in natural hosts.

Silvestri G, Paiardini M, Pandrea I, Lederman MM, Sodora DL.

J Clin Invest. 2007 Nov;117(11):3148-54. Review.

2.

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.

Kaufmann DE, Kavanagh DG, Pereyra F, Zaunders JJ, Mackey EW, Miura T, Palmer S, Brockman M, Rathod A, Piechocka-Trocha A, Baker B, Zhu B, Le Gall S, Waring MT, Ahern R, Moss K, Kelleher AD, Coffin JM, Freeman GJ, Rosenberg ES, Walker BD.

Nat Immunol. 2007 Nov;8(11):1246-54. Epub 2007 Sep 30.

PMID:
17906628
3.

Severe depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection.

Chase AJ, Sedaghat AR, German JR, Gama L, Zink MC, Clements JE, Siliciano RF.

J Virol. 2007 Dec;81(23):12748-57. Epub 2007 Sep 12.

4.

Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection.

Boasso A, Vaccari M, Hryniewicz A, Fuchs D, Nacsa J, Cecchinato V, Andersson J, Franchini G, Shearer GM, Chougnet C.

J Virol. 2007 Nov;81(21):11593-603. Epub 2007 Aug 22.

5.

Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.

Milush JM, Reeves JD, Gordon SN, Zhou D, Muthukumar A, Kosub DA, Chacko E, Giavedoni LD, Ibegbu CC, Cole KS, Miamidian JL, Paiardini M, Barry AP, Staprans SI, Silvestri G, Sodora DL.

J Immunol. 2007 Sep 1;179(5):3047-56.

6.

Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.

Pandrea IV, Gautam R, Ribeiro RM, Brenchley JM, Butler IF, Pattison M, Rasmussen T, Marx PA, Silvestri G, Lackner AA, Perelson AS, Douek DC, Veazey RS, Apetrei C.

J Immunol. 2007 Sep 1;179(5):3035-46.

7.

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.

Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G.

J Immunol. 2007 Sep 1;179(5):3026-34.

8.

Indoleamine-2, 3-dioxygenase and other interferon-gamma-mediated pathways in patients with human immunodeficiency virus infection.

Schroecksnadel K, Zangerle R, Bellmann-Weiler R, Garimorth K, Weiss G, Fuchs D.

Curr Drug Metab. 2007 Apr;8(3):225-36. Review.

PMID:
17430111
9.

How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation.

Boasso A, Shearer GM.

Curr Drug Metab. 2007 Apr;8(3):217-23. Review.

PMID:
17430110
10.

Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation.

Makita S, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Yamamoto M, Kiyono H, Watanabe M.

J Immunol. 2007 Apr 15;178(8):4937-46.

11.

Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques.

Hryniewicz A, Price DA, Moniuszko M, Boasso A, Edghill-Spano Y, West SM, Venzon D, Vaccari M, Tsai WP, Tryniszewska E, Nacsa J, Villinger F, Ansari AA, Trindade CJ, Morre M, Brooks D, Arlen P, Brown HJ, Kitchen CM, Zack JA, Douek DC, Shearer GM, Lewis MG, Koup RA, Franchini G.

J Immunol. 2007 Mar 15;178(6):3492-504.

12.

Simian immunodeficiency virus (SIV) infection influences the level and function of regulatory T cells in SIV-infected rhesus macaques but not SIV-infected sooty mangabeys.

Pereira LE, Villinger F, Onlamoon N, Bryan P, Cardona A, Pattanapanysat K, Mori K, Hagen S, Picker L, Ansari AA.

J Virol. 2007 May;81(9):4445-56. Epub 2007 Feb 21.

13.

Natural regulatory T cells: mechanisms of suppression.

Miyara M, Sakaguchi S.

Trends Mol Med. 2007 Mar;13(3):108-16. Epub 2007 Jan 24. Review.

PMID:
17257897
14.

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.

Boasso A, Herbeuval JP, Hardy AW, Anderson SA, Dolan MJ, Fuchs D, Shearer GM.

Blood. 2007 Apr 15;109(8):3351-9. Epub 2006 Dec 7.

15.

Microbial translocation is a cause of systemic immune activation in chronic HIV infection.

Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC.

Nat Med. 2006 Dec;12(12):1365-71. Epub 2006 Nov 19.

PMID:
17115046
16.

Do regulatory T-cells play a role in AIDS pathogenesis?

Boasso A, Vaccari M, Nilsson J, Shearer GM, Andersson J, Cecchinato V, Chougnet C, Franchini G.

AIDS Rev. 2006 Jul-Sep;8(3):141-7. Review.

PMID:
17078484
17.

Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection.

Mehandru S, Poles MA, Tenner-Racz K, Manuelli V, Jean-Pierre P, Lopez P, Shet A, Low A, Mohri H, Boden D, Racz P, Markowitz M.

J Virol. 2007 Jan;81(2):599-612. Epub 2006 Oct 25.

18.

HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

Nilsson J, Boasso A, Velilla PA, Zhang R, Vaccari M, Franchini G, Shearer GM, Andersson J, Chougnet C.

Blood. 2006 Dec 1;108(12):3808-17. Epub 2006 Aug 10.

19.

CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques.

Hryniewicz A, Boasso A, Edghill-Smith Y, Vaccari M, Fuchs D, Venzon D, Nacsa J, Betts MR, Tsai WP, Heraud JM, Beer B, Blanset D, Chougnet C, Lowy I, Shearer GM, Franchini G.

Blood. 2006 Dec 1;108(12):3834-42. Epub 2006 Aug 8. Erratum in: Blood. 2009 Oct 1;114(14):3132.

20.

Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responses.

Malkevitch NV, Patterson LJ, Aldrich MK, Wu Y, Venzon D, Florese RH, Kalyanaraman VS, Pal R, Lee EM, Zhao J, Cristillo A, Robert-Guroff M.

Virology. 2006 Sep 15;353(1):83-98. Epub 2006 Jun 30.

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