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Results: 1 to 20 of 40

1.

The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.

Stracker TH, Morales M, Couto SS, Hussein H, Petrini JH.

Nature. 2007 May 10;447(7141):218-21. Epub 2007 Apr 11.

PMID:
17429352
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties.

Bowie MB, Kent DG, Dykstra B, McKnight KD, McCaffrey L, Hoodless PA, Eaves CJ.

Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):5878-82. Epub 2007 Mar 22.

PMID:
17379664
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tumor promoting properties of the ETS protein MEF in ovarian cancer.

Yao JJ, Liu Y, Lacorazza HD, Soslow RA, Scandura JM, Nimer SD, Hedvat CV.

Oncogene. 2007 Jun 7;26(27):4032-7. Epub 2007 Jan 8.

PMID:
17213815
[PubMed - indexed for MEDLINE]
4.

A Limited role for p21Cip1/Waf1 in maintaining normal hematopoietic stem cell functioning.

van Os R, Kamminga LM, Ausema A, Bystrykh LV, Draijer DP, van Pelt K, Dontje B, de Haan G.

Stem Cells. 2007 Apr;25(4):836-43. Epub 2006 Dec 14.

PMID:
17170062
[PubMed - indexed for MEDLINE]
Free Article
5.

Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect.

Bowie MB, McKnight KD, Kent DG, McCaffrey L, Hoodless PA, Eaves CJ.

J Clin Invest. 2006 Oct;116(10):2808-16.

PMID:
17016561
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Repair of topoisomerase I-mediated DNA damage.

Pommier Y, Barcelo JM, Rao VA, Sordet O, Jobson AG, Thibaut L, Miao ZH, Seiler JA, Zhang H, Marchand C, Agama K, Nitiss JL, Redon C.

Prog Nucleic Acid Res Mol Biol. 2006;81:179-229. Review. No abstract available.

PMID:
16891172
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Rad50S alleles of the Mre11 complex: questions answered and questions raised.

Usui T, Petrini JH, Morales M.

Exp Cell Res. 2006 Aug 15;312(14):2694-9. Epub 2006 Jun 20. Review.

PMID:
16857186
[PubMed - indexed for MEDLINE]
8.

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells.

Lacorazza HD, Yamada T, Liu Y, Miyata Y, Sivina M, Nunes J, Nimer SD.

Cancer Cell. 2006 Mar;9(3):175-87.

PMID:
16530702
[PubMed - indexed for MEDLINE]
Free Article
9.

The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.

Morales M, Theunissen JW, Kim CF, Kitagawa R, Kastan MB, Petrini JH.

Genes Dev. 2005 Dec 15;19(24):3043-54.

PMID:
16357220
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets.

Sieburg HB, Cho RH, Dykstra B, Uchida N, Eaves CJ, Muller-Sieburg CE.

Blood. 2006 Mar 15;107(6):2311-6. Epub 2005 Nov 15.

PMID:
16291588
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.

Neale MJ, Pan J, Keeney S.

Nature. 2005 Aug 18;436(7053):1053-7.

PMID:
16107854
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae.

Deng C, Brown JA, You D, Brown JM.

Genetics. 2005 Jun;170(2):591-600. Epub 2005 Apr 16.

PMID:
15834151
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate.

Shaffer DR, Viale A, Ishiwata R, Leversha M, Olgac S, Manova K, Satagopan J, Scher H, Koff A.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):210-5. Epub 2004 Dec 22.

PMID:
15615849
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together.

Stracker TH, Theunissen JW, Morales M, Petrini JH.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):845-54. Review.

PMID:
15279769
[PubMed - indexed for MEDLINE]
15.

Repair of DNA covalently linked to protein.

Connelly JC, Leach DR.

Mol Cell. 2004 Feb 13;13(3):307-16. Review.

PMID:
14967139
[PubMed - indexed for MEDLINE]
Free Article
16.

Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice.

Theunissen JW, Kaplan MI, Hunt PA, Williams BR, Ferguson DO, Alt FW, Petrini JH.

Mol Cell. 2003 Dec;12(6):1511-23.

PMID:
14690604
[PubMed - indexed for MEDLINE]
Free Article
17.

Biology of hematopoietic stem cells and progenitors: implications for clinical application.

Kondo M, Wagers AJ, Manz MG, Prohaska SS, Scherer DC, Beilhack GF, Shizuru JA, Weissman IL.

Annu Rev Immunol. 2003;21:759-806. Epub 2002 Dec 17. Review.

PMID:
12615892
[PubMed - indexed for MEDLINE]
18.

p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development.

Carneiro C, Jiao MS, Hu M, Shaffer D, Park M, Pandolfi PP, Cordon-Cardo C, Koff A.

Oncogene. 2003 Jan 23;22(3):361-9.

PMID:
12545157
[PubMed - indexed for MEDLINE]
19.

Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

Liu C, Pouliot JJ, Nash HA.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14970-5. Epub 2002 Oct 23.

PMID:
12397185
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage.

Vance JR, Wilson TE.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13669-74. Epub 2002 Oct 4.

PMID:
12368472
[PubMed - indexed for MEDLINE]
Free PMC Article

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